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公开(公告)号：US20070169222A1
公开(公告)日：2007-07-19
申请号：US11552603
申请日：2006-10-25
申请人： Michelle Verbsky , Catherine Baublite , Andrew Kloek , Jennifer Davila-Aponte , Michelle Hresko , Merry McLaird , Rodolfo Zentella , Deryck Williams
发明人： Michelle Verbsky , Catherine Baublite , Andrew Kloek , Jennifer Davila-Aponte , Michelle Hresko , Merry McLaird , Rodolfo Zentella , Deryck Williams
CPC分类号： C12N9/0071 , C11B1/00 , C12N9/0073 , C12N15/8223 , C12N15/8247 , C12N15/8285 , Y02A40/164
摘要： The present invention provides DNA constructs, transgenic plants containing such constructs, and methods of making the plants. The DNA constructs encode a polypeptide that when expressed results in the production of fatty acid compounds having anthelmintic activity. Transgenic plants expressing such a polypeptide can exhibit enhanced resistance to plant parasitic nematodes, particularly when expressed in vegetative tissues. Transgenic plants expressing such a polypeptide can also be useful for non-pesticidal industrial uses.
摘要翻译： 本发明提供了DNA构建体，含有这种构建体的转基因植物和制备植物的方法。 DNA构建体编码多肽，当表达导致产生具有驱肠虫活性的脂肪酸化合物时。 表达这种多肽的转基因植物可以表现出对植物寄生线虫的增强的抗性，特别是当在营养组织中表达时。 表达这种多肽的转基因植物也可用于非农药工业用途。
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公开(公告)号：US20050172358A1
公开(公告)日：2005-08-04
申请号：US10912534
申请日：2004-08-04
申请人： Michelle Verbsky , Catherine Baublite , Andrew Kloek , Jennifer Davila-Aponte , Michelle Hresko , Merry McLaird , Rodolfo Zentella , Deryck Williams
发明人： Michelle Verbsky , Catherine Baublite , Andrew Kloek , Jennifer Davila-Aponte , Michelle Hresko , Merry McLaird , Rodolfo Zentella , Deryck Williams
CPC分类号： C12N9/0071 , C11B1/00 , C12N9/0073 , C12N15/8223 , C12N15/8247 , C12N15/8285 , Y02A40/164
摘要： The present invention provides DNA constructs, transgenic plants containing such constructs, and methods of making the plants. The DNA constructs encode a polypeptide that when expressed results in the production of fatty acid compounds having anthelmintic activity. Transgenic plants expressing such a polypeptide can exhibit enhanced resistance to plant parasitic nematodes, particularly when expressed in vegetative tissues. Transgenic plants expressing such a polypeptide can also be useful for non-pesticidal industrial uses.
摘要翻译： 本发明提供了DNA构建体，含有这种构建体的转基因植物和制备植物的方法。 DNA构建体编码多肽，当表达导致产生具有驱肠虫活性的脂肪酸化合物时。 表达这种多肽的转基因植物可以表现出对植物寄生线虫的增强的抗性，特别是当在营养组织中表达时。 表达这种多肽的转基因植物也可用于非农药工业用途。
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公开(公告)号：US20070266461A1
公开(公告)日：2007-11-15
申请号：US11552681
申请日：2006-10-25
申请人： Michelle Verbsky , Catherine Baublite , Deryck Williams , Andrew Kloek , Jennifer Davila-Aponte , Michelle Hresko , Merry McLaird , Rodolfo Zentella
发明人： Michelle Verbsky , Catherine Baublite , Deryck Williams , Andrew Kloek , Jennifer Davila-Aponte , Michelle Hresko , Merry McLaird , Rodolfo Zentella
IPC分类号： A01H5/00
CPC分类号： C12N15/8285 , C12N15/8247 , Y02A40/164 , Y02A40/166
摘要： The present invention provides DNA constructs, transgenic plants containing such constructs, and methods of making the plants. The DNA constructs encode a polypeptide that when expressed results in the production of fatty acid compounds having anthelmintic activity. Transgenic plants expressing such a polypeptide can exhibit enhanced resistance to plant parasitic nematodes, particularly when expressed in vegetative tissues.
摘要翻译： 本发明提供DNA构建体，含有这种构建体的转基因植物，以及制备植物的方法。 DNA构建体编码多肽，当表达导致产生具有驱肠虫活性的脂肪酸化合物时。 表达这种多肽的转基因植物可以表现出对植物寄生线虫的增强的抗性，特别是当在营养组织中表达时。
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公开(公告)号：US20050260674A1
公开(公告)日：2005-11-24
申请号：US11191375
申请日：2005-07-28
申请人： Michelle Hresko , Merry McLaird , Deryck Williams , Anita Frevert , Brandi Chiapelli , Catherine Baublite , Andrew Kloek , Jennifer Davila-Aponte , John Bradley , Siqun Xu
发明人： Michelle Hresko , Merry McLaird , Deryck Williams , Anita Frevert , Brandi Chiapelli , Catherine Baublite , Andrew Kloek , Jennifer Davila-Aponte , John Bradley , Siqun Xu
IPC分类号： A61K38/17 , C07H21/04 , C07K1/00 , C07K14/00 , C07K14/435 , C07K14/705 , C07K17/00 , C12N20060101 , C12N15/00 , C12P21/06 , C12Q1/68
CPC分类号： C07K14/705
摘要： Nucleic acid molecules from nematodes encoding PAN and ZP domain containing receptor polypeptides are described. PANZP polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of PANZP nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators, as well as methods for antibody production.
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公开(公告)号：US20050260673A1
公开(公告)日：2005-11-24
申请号：US11191374
申请日：2005-07-28
申请人： Michelle Hresko , Merry McLaird , Deryck Williams , Anita Frevert , Brandi Chiapelli , Catherine Baublite , Andrew Kloek , Jennifer Davila-Aponte , John Bradley , Siqun Xu
发明人： Michelle Hresko , Merry McLaird , Deryck Williams , Anita Frevert , Brandi Chiapelli , Catherine Baublite , Andrew Kloek , Jennifer Davila-Aponte , John Bradley , Siqun Xu
IPC分类号： A61K38/17 , C07H21/04 , C07K1/00 , C07K14/00 , C07K14/435 , C07K14/705 , C07K17/00 , C12N20060101 , C12N15/00 , C12P21/06 , C12Q1/68
CPC分类号： C07K14/705
摘要： Nucleic acid molecules from nematodes encoding PAN and ZP domain containing receptor polypeptides are described. PANZP polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of PANZP nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators, as well as methods for antibody production.
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公开(公告)号：US20050282222A1
公开(公告)日：2005-12-22
申请号：US11191588
申请日：2005-07-28
申请人： Michelle Hresko , Merry McLaird , Deryck Williams , Anita Frevert , Brandi Chiapelli , Catherine Baublite , Andrew Kloek , Jennifer Davila-Aponte , John Bradley , Siqun Xu
发明人： Michelle Hresko , Merry McLaird , Deryck Williams , Anita Frevert , Brandi Chiapelli , Catherine Baublite , Andrew Kloek , Jennifer Davila-Aponte , John Bradley , Siqun Xu
IPC分类号： A61K38/17 , C07H21/04 , C07K1/00 , C07K14/00 , C07K14/435 , C07K14/705 , C07K17/00 , C12N20060101 , C12N15/00 , C12P21/06 , C12Q1/68
CPC分类号： C07K14/705
摘要： Nucleic acid molecules from nematodes encoding PAN and ZP domain containing receptor polypeptides are described. PANZP polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of PANZP nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators, as well as methods for antibody production.
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公开(公告)号：US20070009981A1
公开(公告)日：2007-01-11
申请号：US11326080
申请日：2006-01-05
申请人： Deryck Williams , Merry McLaird , Michelle Hresko , Anita Frevert-Thompson , Ronald Worthington , Andrew Kloek , Jennifer Davila-Aponte , John Bradley , Siqun Xu
发明人： Deryck Williams , Merry McLaird , Michelle Hresko , Anita Frevert-Thompson , Ronald Worthington , Andrew Kloek , Jennifer Davila-Aponte , John Bradley , Siqun Xu
CPC分类号： C12N9/1007
摘要： Nucleic acid molecules from nematodes encoding phosphoethanolamine n-methyltransferase polypeptides are described. PEAMT-like polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of PEAMT-like nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators, as well as methods for antibody production.
摘要翻译： 描述了编码磷酸乙醇胺正甲基转移酶多肽的线虫的核酸分子。 还提供了PEAMT样多肽序列，载体，宿主细胞和用于产生PEAMT样核苷酸和多肽的重组方法也是如此。 还描述了用于鉴定抑制剂和/或激活剂的筛选方法以及用于抗体生产的方法。
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公开(公告)号：US20050257290A1
公开(公告)日：2005-11-17
申请号：US11060008
申请日：2005-02-17
申请人： Andrew Kloek , Deryck Williams , Merry McLaird , John Bradley , Jennifer Davila-Aponte , Siqun Xu , Anita Frevert
发明人： Andrew Kloek , Deryck Williams , Merry McLaird , John Bradley , Jennifer Davila-Aponte , Siqun Xu , Anita Frevert
CPC分类号： C12N9/0083 , C12N15/8247 , C12N15/8285 , G01N33/573 , G01N2333/4353 , Y02A40/164
摘要： Nucleic acid molecules from nematodes encoding fatty acid desaturase polypeptides are described. Fatty acid desaturase-like polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of fatty acid desaturase-like nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators of fatty acid desaturase-like polypeptides, as well as methods for antibody production.
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公开(公告)号：US20050277132A1
公开(公告)日：2005-12-15
申请号：US11059867
申请日：2005-02-17
申请人： Andrew Kloek , Deryck Williams , Brandy Salmon , Merry McLaird
发明人： Andrew Kloek , Deryck Williams , Brandy Salmon , Merry McLaird
CPC分类号： C12N9/93 , C12Q1/25 , C12Y603/01002 , G01N2500/00
摘要： Disclosed is a nucleic acid molecule from nematodes encoding for glutamine synthetase (GS) polypeptides. The GS-like polypeptide sequence is also provided, as are vectors, host cells, and recombinant methods for production of GS-like nucleotides and polypeptides. The invention further relates to screening methods for identifying inhibitors and/or activators, as well as methods for antibody production.
摘要翻译： 公开了编码谷氨酰胺合成酶（GS）多肽的线虫的核酸分子。 还提供GS样多肽序列，载体，宿主细胞以及用于产生GS样核苷酸和多肽的重组方法。 本发明还涉及用于鉴定抑制剂和/或激活剂的筛选方法以及用于抗体生产的方法。
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公开(公告)号：US20050198695A1
公开(公告)日：2005-09-08
申请号：US11091969
申请日：2005-03-28
申请人： Deryck Williams , Brandy Salmon , Andrew Kloek
发明人： Deryck Williams , Brandy Salmon , Andrew Kloek
CPC分类号： C07K14/4354 , G01N33/573 , G01N2500/04
摘要： Nucleic acid molecules from nematodes encoding ATP synthase subunit E polypeptides are described. ATP synthase subunit E-like polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of ATP synthase subunit E-like nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators, as well as methods for antibody production.
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