公开(公告)号：US4780477A

公开(公告)日：1988-10-25

申请号：US868146

申请日：1986-05-29

申请人： Michihiro Kobayashi ,  Makio Kitazawa ,  Masuo Akahane ,  Tsutomu Tsukamoto ,  Ryoji Yamamoto ,  Yasushi Nakano

发明人： Michihiro Kobayashi ,  Makio Kitazawa ,  Masuo Akahane ,  Tsutomu Tsukamoto ,  Ryoji Yamamoto ,  Yasushi Nakano

IPC分类号： A61K31/40 ,  A61K31/403 ,  A61K31/404 ,  A61P1/04 ,  C07D209/40 ,  C07D209/34

CPC分类号： C07D209/40

摘要： This invention provides novel isatin compounds which are useful as therapeutic agents. The invention isatin compounds and the pharmaceutically acceptable salts thereof exhibit anti-ulcer activities which are applicable for propylaxis and treatment of ulcer diseases in the digestive tract of animals.

摘要翻译： 本发明提供了可用作治疗剂的新型靛红化合物。 本发明的靛红化合物及其药学上可接受的盐具有抗菌活性，其适用于动物消化道中的丙肟酸和溃疡性疾病的治疗。

公开(公告)号：US5177069A

公开(公告)日：1993-01-05

申请号：US623107

申请日：1990-12-06

申请人： Makio Kitazawa ,  Masuo Akahane ,  Yasushi Nakano ,  Atsushi Tsubaki ,  Kazuaki Sato ,  Masaaki Ban ,  Michihiro Kobayashi

发明人： Makio Kitazawa ,  Masuo Akahane ,  Yasushi Nakano ,  Atsushi Tsubaki ,  Kazuaki Sato ,  Masaaki Ban ,  Michihiro Kobayashi

IPC分类号： C07C317/44 ,  C07C323/52

CPC分类号： C07C323/52 ,  C07C317/44

摘要： The present invention provides a novel class of naphthylsulfonylalkanoic acid compounds such as a structure corrresponding to the formula: ##STR1## or a pharmaceutically acceptable salt thereof. A present invention naphthylsulfonylalkanoic acid compound is useful for prevention or treatment of irritable bowel syndrome, biliary dyskinesia and acute pancreatitis.

公开(公告)号：US5145869A

公开(公告)日：1992-09-08

申请号：US683247

申请日：1991-04-11

申请人： Makio Kitazawa ,  Masuo Akahane ,  Yasushi Nakano ,  Atsushi Tsubaki ,  Kazuaki Sato ,  Masaaki Ban ,  Michihiro Kobayashi

发明人： Makio Kitazawa ,  Masuo Akahane ,  Yasushi Nakano ,  Atsushi Tsubaki ,  Kazuaki Sato ,  Masaaki Ban ,  Michihiro Kobayashi

IPC分类号： C07C317/44 ,  C07C323/60

CPC分类号： C07C317/44 ,  C07C323/60

摘要： The present invention provides a novel class of phenylsulfonylalkanoic acid compounds such as a structure corresponding to the formula: ##STR1## or a pharmaceutically acceptable salt thereof. A present invention phenylsulfonylalkanoic acid compound is useful for prevention or treatment of irritable bowel syndrome, biliary dyskinesia and acute pancreatitis.

摘要翻译： 本发明提供了一类新的苯基磺酰基链烷酸化合物，例如对应于下式的结构：或其药学上可接受的盐。 本发明苯磺酰基链烷酸化合物可用于预防或治疗肠易激综合征，胆道运动障碍和急性胰腺炎。

公开(公告)号：US20070278694A1

公开(公告)日：2007-12-06

申请号：US11806231

申请日：2007-05-30

申请人： Michihiro Kobayashi ,  Hirofumi Nikaido ,  Nobuyuki Katsuki ,  Yasuhiro Kawakatsu

发明人： Michihiro Kobayashi ,  Hirofumi Nikaido ,  Nobuyuki Katsuki ,  Yasuhiro Kawakatsu

IPC分类号： H01L23/48

CPC分类号： H01L23/522 ,  H01L21/76816 ,  H01L21/76895 ,  H01L23/5226 ,  H01L27/11 ,  H01L2924/0002 ,  H01L2924/00

摘要： Two interconnect layers are electrically connected while reducing the number of manufacturing steps. A contact plug 9c which is formed into a beaded shape in a layer underlying two interconnects 11C and 11D and which also electrically connects the two interconnects 11C and 11D is included. The two interconnects 11C and 11D are separated to each other and are formed in a same layer. The contact plug 9c is simultaneously formed with a contact plug 9b to be connected to an interconnect 4b and a contact plug 9a to be connected to a source/drain region 6.

摘要翻译： 两个互连层电连接，同时减少制造步骤的数量。 包括在两个互连11C和11D下面的层中形成为串珠形状并且还电连接两个互连11C和11D的接触插塞9c。 两个互连11C和11D彼此分离并且形成在相同的层中。 接触插头9c同时形成有接触插头9b，以连接到互连件4b和连接到源极/漏极区域6的接触插塞9a。

公开(公告)号：USRE32944E

公开(公告)日：1989-06-06

申请号：US802486

申请日：1977-06-01

申请人： Kozaburo Harita ,  Yukiyoshi Ajisawa ,  Kinji Iizuka ,  Yukihiko Kinoshita ,  Tetsuhide Kamijo ,  Michihiro Kobayashi

发明人： Kozaburo Harita ,  Yukiyoshi Ajisawa ,  Kinji Iizuka ,  Yukihiko Kinoshita ,  Tetsuhide Kamijo ,  Michihiro Kobayashi

IPC分类号： C07C233/33 ,  A61K31/195 ,  A61P37/08 ,  C07C67/00 ,  C07C231/00 ,  C07C231/02 ,  C07C231/12 ,  C07C233/12 ,  C07C233/55 ,  C07C235/38 ,  C07D317/60

CPC分类号： A61K31/195 ,  C07C233/12

摘要： Novel aromatic carboxylic amides of the general formula: ##STR1## wherein each of R.sub.1 and R.sub.2 is a hydrogen atom or an alkyl group having 1-4 carbon atoms, R.sub.3 and R.sub.4 are hydrogen atoms or together form another chemical bond, each X is a hydroxyl group, a halogen atom, an alkyl group having 1-4 carbon atoms and an alkoxy group containing 1-4 carbon atoms, and n is an integer of 1-3 with the proviso that when .[.Xs.]. .Iadd.X's .Iaddend.are alkyl or alkoxy groups, they may be connected together to form a ring, as well as pharmaceutically acceptable salts thereof.These compounds possess a strong antiallergenic action and are thus useful for treatment of asthma, hay fever, .[.anticaria.]. .Iadd.urticaria .Iaddend.and atopic dermatitis.The above aromatic carboxylic amides can be prepared by reacting a reactive functional derivative of the general formula: ##STR2## where R.sub.1, R.sub.2, R.sub.3, R.sub.4, X and n have the same meanings given above, with an aminobenzoic acid of the formula: ##STR3## and, if desired, converting the resulting amide into the corresponding salts.

公开(公告)号：US07923843B2

公开(公告)日：2011-04-12

申请号：US11806231

申请日：2007-05-30

申请人： Michihiro Kobayashi ,  Hirofumi Nikaido ,  Nobuyuki Katsuki ,  Yasuhiro Kawakatsu

发明人： Michihiro Kobayashi ,  Hirofumi Nikaido ,  Nobuyuki Katsuki ,  Yasuhiro Kawakatsu

IPC分类号： H01L23/48

CPC分类号： H01L23/522 ,  H01L21/76816 ,  H01L21/76895 ,  H01L23/5226 ,  H01L27/11 ,  H01L2924/0002 ,  H01L2924/00

摘要： Two interconnect layers are electrically connected while reducing the number of manufacturing steps. A contact plug 9c which is formed into a beaded shape in a layer underlying two interconnects 11C and 11D and which also electrically connects the two interconnects 11C and 11D is included. The two interconnects 11C and 11D are separated to each other and are formed in a same layer. The contact plug 9c is simultaneously formed with a contact plug 9b to be connected to an interconnect 4b and a contact plug 9a to be connected to a source/drain region 6.

摘要翻译： 两个互连层电连接，同时减少制造步骤的数量。 包括在两个互连11C和11D下面的层中形成为串珠形状并且还电连接两个互连11C和11D的接触插塞9c。 两个互连11C和11D彼此分离并形成在相同的层中。 接触插头9c同时形成有接触插头9b以连接到互连件4b和接触插头9a以连接到源极/漏极区域6。

公开(公告)号：US07593252B2

公开(公告)日：2009-09-22

申请号：US11798736

申请日：2007-05-16

申请人： Nobuyuki Katsuki ,  Hirofumi Nikaido ,  Michihiro Kobayashi ,  Yasuhiro Kawakatsu

发明人： Nobuyuki Katsuki ,  Hirofumi Nikaido ,  Michihiro Kobayashi ,  Yasuhiro Kawakatsu

IPC分类号： G11C11/00

CPC分类号： G11C11/412 ,  H01L27/1104

摘要： A semiconductor apparatus includes an internal layer where a first power supply line to provide a first power supply to transistors in a layout cell and an internal cell line to connect transistors in the layout cell are placed, an input/output line connected with an input/output terminal of the layout cell is placed, and a shield line which is placed between the internal layer and the input/output line so as to cover the internal layer and the first power supply line.

摘要翻译： 一种半导体装置，包括内部层，其中设置有用于向布局单元中的晶体管提供第一电源的第一电源线和用于连接布局单元中的晶体管的内部单元线路，与输入/ 放置布局单元的输出端子，以及屏蔽线，其被布置在内层和输入/输出线之间以覆盖内层和第一电源线。

公开(公告)号：US5202335A

公开(公告)日：1993-04-13

申请号：US860023

申请日：1992-03-30

申请人： Fumiyasu Sato ,  Atsushi Tsubaki ,  Hiroshi Hokari ,  Nobuyuki Tanaka ,  Masaru Saito ,  Kenji Akahane ,  Michihiro Kobayashi

发明人： Fumiyasu Sato ,  Atsushi Tsubaki ,  Hiroshi Hokari ,  Nobuyuki Tanaka ,  Masaru Saito ,  Kenji Akahane ,  Michihiro Kobayashi

IPC分类号： C07D209/08 ,  C07D209/44 ,  C07D217/06 ,  C07D409/06

CPC分类号： C07D409/06 ,  C07D209/08 ,  C07D209/44 ,  C07D217/06

摘要： Succinic acid compounds of the formula: ##STR1## wherein A represents a heterocyclic group, a 3 to 8-membered cycloalkyl group or a phenyl group which may have one or more substituents selected from the group of a halogen atom, a lower alkyl group having 1 to 6 carbon atoms and a lower alkoxy group having 1 to 6 carbon atoms; B represents a bicyclic amino group which may have 1 or 2 unsaturated bonds, with the proviso that B bonds to the carbon atom of the carbonyl group at the nitrogen atom; R represents a hydrogen atom or combines each other to form a chemical bond; R.sup.1 represents a hydrogen atom, a lower alkyl group having 1 to 6 carbon atoms or an aralkyl group having 7 to 10 carbon atoms; when there is an asymmetric carbon atom, enantiomers thereof and racemic mixtures thereof; when there are geometrical isomers, each geometrical isomer, E-isomers thereof, Z-isomers thereof, cis-isomers thereof and trans-isomers thereof; and pharmaceutically acceptable salts thereof, enhance insulin secretion and possess a hypoglycemic activity, and are thus useful for the treatment of diabetes.

公开(公告)号：US07719042B2

公开(公告)日：2010-05-18

申请号：US11812192

申请日：2007-06-15

申请人： Yasuhiro Kawakatsu ,  Hitoshi Abiko ,  Hirofumi Nikaido ,  Nobuyuki Katsuki ,  Michihiro Kobayashi

发明人： Yasuhiro Kawakatsu ,  Hitoshi Abiko ,  Hirofumi Nikaido ,  Nobuyuki Katsuki ,  Michihiro Kobayashi

IPC分类号： H01L27/108

CPC分类号： H01L27/1104 ,  H01L27/11

摘要： A lower electrode projects outward from a common end face of an upper electrode and a capacitor film. A protective film, which is made of a different material from the capacitor film, is deposited on top of a part of the lower electrode outside the end face. The protective film also extends to the position at a certain distance inward from the end face, so that it is placed between the capacitor film and the lower electrode. The capacitor film thereby has a stepped surface near the end face due to the presence of the protective film, which suppresses the progress of damage during etching of the upper electrode and the capacitor film. Further, the protective film prevents the occurrence of damage in the lower electrode.

摘要翻译： 下电极从上电极和电容器膜的公共端面向外突出。 由与电容器膜不同的材料制成的保护膜沉积在端面外部的一部分下部电极的顶部。 保护膜也从端面向内延伸到一定距离的位置，使其保持在电容器膜和下电极之间。 由于存在保护膜，因此电容器膜具有靠近端面的台阶表面，这抑制了上电极和电容器膜的蚀刻期间的损坏进展。 此外，保护膜防止在下电极中发生损坏。

公开(公告)号：US20080001197A1

公开(公告)日：2008-01-03

申请号：US11812192

申请日：2007-06-15

申请人： Yasuhiro Kawakatsu ,  Hitoshi Abiko ,  Hirofumi Nikaido ,  Nobuyuki Katsuki ,  Michihiro Kobayashi

发明人： Yasuhiro Kawakatsu ,  Hitoshi Abiko ,  Hirofumi Nikaido ,  Nobuyuki Katsuki ,  Michihiro Kobayashi

IPC分类号： H01L27/11 ,  H01L21/8244

CPC分类号： H01L27/1104 ,  H01L27/11

摘要： A lower electrode projects outward from a common end face of an upper electrode and a capacitor film. A protective film, which is made of a different material from the capacitor film, is deposited on top of a part of the lower electrode outside the end face. The protective film also extends to the position at a certain distance inward from the end face, so that it is placed between the capacitor film and the lower electrode. The capacitor film thereby has a stepped surface near the end face due to the presence of the protective film, which suppresses the progress of damage during etching of the upper electrode and the capacitor film. Further, the protective film prevents the occurrence of damage in the lower electrode.

摘要翻译： 下电极从上电极和电容器膜的公共端面向外突出。 由与电容器膜不同的材料制成的保护膜沉积在端面外部的一部分下部电极的顶部。 保护膜也从端面向内延伸到一定距离的位置，使其保持在电容器膜和下电极之间。 由于存在保护膜，因此电容器膜具有靠近端面的台阶表面，这抑制了上电极和电容器膜的蚀刻期间的损坏进展。 此外，保护膜防止在下电极中发生损坏。