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公开(公告)号：US08647589B2
公开(公告)日：2014-02-11
申请号：US13554380
申请日：2012-07-20
申请人： Tsutomu Horiuchi , Toru Miura , Yuzuru Iwasaki , Jyunichi Takahashi , Katsuyoshi Hayashi , Tsuneyuki Haga , Michiko Seyama , Serge Camou
发明人： Tsutomu Horiuchi , Toru Miura , Yuzuru Iwasaki , Jyunichi Takahashi , Katsuyoshi Hayashi , Tsuneyuki Haga , Michiko Seyama , Serge Camou
IPC分类号： B01L3/00
CPC分类号： G01N35/1095 , B01L3/502707 , B01L3/502761 , B01L2200/0673 , B01L2200/12 , B01L2300/0816 , B01L2300/0887 , B01L2400/0406
摘要： An object of the invention is to provide various flow cells and a method for manufacturing the same, in which formation of a groove on a substrate and formation of components such as an electrode, auxiliary parts such as a pump are not necessary. The inventive flow cells are capable of realize complicated chemical analysis or synthesis or the like. A channel of a porous member provided on a sample-incompatible substrate is formed; the porous member is composed of an air non-contact region having a network structure and an air contact region covering the air non-contact region and having a lower pore density than the air non-contact region; in which a capillary force to be generated within the porous member is a drive force for pumping a liquid.
摘要翻译： 本发明的目的是提供各种流动池及其制造方法，其中不需要在基板上形成凹槽并形成诸如电极的部件，诸如泵的辅助部件。 本发明的流动池能够实现复杂的化学分析或合成等。 形成设置在样品不相容基板上的多孔构件的通道; 多孔构件由具有网状结构的空气非接触区域和覆盖空气非接触区域的空气接触区域构成，并且具有比空气非接触区域低的孔密度; 其中在多孔构件内产生的毛细管力是泵送液体的驱动力。
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公开(公告)号：US20120288421A1
公开(公告)日：2012-11-15
申请号：US13554380
申请日：2012-07-20
申请人： Tsutomu Horiuchi , Toru Miura , Yuzuru Iwasaki , Jyunichi Takahashi , Katsuyoshi Hayashi , Tsuneyuki Haga , Michiko Seyama , Serge Camou
发明人： Tsutomu Horiuchi , Toru Miura , Yuzuru Iwasaki , Jyunichi Takahashi , Katsuyoshi Hayashi , Tsuneyuki Haga , Michiko Seyama , Serge Camou
IPC分类号： B01L3/00
CPC分类号： G01N35/1095 , B01L3/502707 , B01L3/502761 , B01L2200/0673 , B01L2200/12 , B01L2300/0816 , B01L2300/0887 , B01L2400/0406
摘要： An object of the invention is to provide various flow cells and a method for manufacturing the same, in which formation of a groove on a substrate and formation of components such as an electrode, auxiliary parts such as a pump are not necessary. The inventive flow cells are capable of realize complicated chemical analysis or synthesis or the like. A channel of a porous member provided on a sample-incompatible substrate is formed; the porous member is composed of an air non-contact region having a network structure and an air contact region covering the air non-contact region and having a lower pore density than the air non-contact region; in which a capillary force to be generated within the porous member is a drive force for pumping a liquid.
摘要翻译： 本发明的目的是提供各种流动池及其制造方法，其中不需要在基板上形成凹槽并形成诸如电极的部件，诸如泵的辅助部件。 本发明的流动池能够实现复杂的化学分析或合成等。 形成设置在样品不相容基板上的多孔构件的通道; 多孔构件由具有网状结构的空气非接触区域和覆盖空气非接触区域的空气接触区域构成，并且具有比空气非接触区域低的孔密度; 其中在多孔构件内产生的毛细管力是泵送液体的驱动力。
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公开(公告)号：US08859267B2
公开(公告)日：2014-10-14
申请号：US12304112
申请日：2007-06-11
申请人： Michiko Seyama , Serge Camou , Yuzuru Iwasaki , Toru Miura , Jyunichi Takahashi , Tsuneyuki Haga , Tsutomu Horiuchi
发明人： Michiko Seyama , Serge Camou , Yuzuru Iwasaki , Toru Miura , Jyunichi Takahashi , Tsuneyuki Haga , Tsutomu Horiuchi
CPC分类号： G01N33/54373 , B01L3/502715 , B01L2200/148 , B01L2300/0645 , B01L2300/069 , B01L2300/0816 , B01L2300/0825 , B01L2300/0861 , B01L2300/0864 , B01L2400/084 , G01N21/553
摘要： The present invention relates to a chip for optical analysis. In particular, the present invention relates to an optical sensor handling a liquid sample, which is a chip for analysis that can be used for selectively measuring a biologically-relevant substance or a chemical substance such as an environmental pollutant or a health affecting substance in a liquid to be measured. The chip for optical analysis of the present invention is characterized in that (1) an adsorption region (filter region) is provided between a sample introduction section and the observation section in a passage of the chip for analysis, (2) a bypass passage is provided in the passage (main passage) of the chip for analysis, and a time lag is generated between samples passed through the main passage and passed through a bypass passage, and (3) a measurement region and a reference region are provided in the observation section of the chip for analysis. In the present invention, the aspects (1) to (3) can be achieved individually or two or more thereof can be combined.
摘要翻译： 本发明涉及一种用于光学分析的芯片。 特别地，本发明涉及一种处理液体样品的光学传感器，该液体样品是可用于选择性地测量生物相关物质或化学物质如环境污染物质或健康影响物质的分析用芯片 要测量的液体 本发明的光学分析用芯片的特征在于，（1）在用于分析的芯片的通路中，在样品导入部和观察部之间设置有吸附区域（滤波区域），（2）旁路通路 设置在用于分析的芯片的通道（主通道）中，并且在通过主通道并穿过旁路通道的样品之间产生时间延迟，并且（3）在观察中提供测量区域和参考区域 芯片部分进行分析。 在本发明中，方面（1）〜（3）可以单独实现，也可以组合2个以上。
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公开(公告)号：US20100233033A1
公开(公告)日：2010-09-16
申请号：US12303943
申请日：2007-06-26
申请人： Tsutomu Horiuchi , Toru Miura , Yuzuru Iwasaki , Jyunichi Takahashi , Katsuyoshi Hayashi , Tsuneyuki Haga , Michiko Seyama , Serge Camou
发明人： Tsutomu Horiuchi , Toru Miura , Yuzuru Iwasaki , Jyunichi Takahashi , Katsuyoshi Hayashi , Tsuneyuki Haga , Michiko Seyama , Serge Camou
CPC分类号： G01N35/1095 , B01L3/502707 , B01L3/502761 , B01L2200/0673 , B01L2200/12 , B01L2300/0816 , B01L2300/0887 , B01L2400/0406
摘要： An object of the invention is to provide various flow cells and a method for manufacturing the same, in which formation of a groove on a substrate and formation of components such as an electrode, auxiliary parts such as a pump are not necessary. The inventive flow cells are capable of realize complicated chemical analysis or synthesis or the like. A channel of a porous member provided on a sample-incompatible substrate is formed; the porous member is composed of an air non-contact region having a network structure and an air contact region covering the air non-contact region and having a lower pore density than the air non-contact region; in which a capillary force to be generated within the porous member is a drive force for pumping a liquid.
摘要翻译： 本发明的目的是提供各种流动池及其制造方法，其中不需要在基板上形成凹槽并形成诸如电极的部件，诸如泵的辅助部件。 本发明的流动池能够实现复杂的化学分析或合成等。 形成设置在样品不相容基板上的多孔构件的通道; 多孔构件由具有网状结构的空气非接触区域和覆盖空气非接触区域的空气接触区域构成，并且具有比空气非接触区域低的孔密度; 其中在多孔构件内产生的毛细管力是泵送液体的驱动力。
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公开(公告)号：US20100248351A1
公开(公告)日：2010-09-30
申请号：US12304112
申请日：2007-06-11
申请人： Michiko Seyama , Serge Camou , Yuzuru Iwasaki , Toru Miura , Jyunichi Takahashi , Tsuneyuki Haga , Tsutomu Horiuchi
发明人： Michiko Seyama , Serge Camou , Yuzuru Iwasaki , Toru Miura , Jyunichi Takahashi , Tsuneyuki Haga , Tsutomu Horiuchi
CPC分类号： G01N33/54373 , B01L3/502715 , B01L2200/148 , B01L2300/0645 , B01L2300/069 , B01L2300/0816 , B01L2300/0825 , B01L2300/0861 , B01L2300/0864 , B01L2400/084 , G01N21/553
摘要： The present invention relates to a chip for optical analysis. In particular, the present invention relates to an optical sensor handling a liquid sample, which is a chip for analysis that can be used for selectively measuring a biologically-relevant substance or a chemical substance such as an environmental pollutant or a health affecting substance in a liquid to be measured. The chip for optical analysis of the present invention is characterized in that (1) an adsorption region (filter region) is provided between a sample introduction section and the observation section in a passage of the chip for analysis, (2) a bypass passage is provided in the passage (main passage) of the chip for analysis, and a time lag is generated between samples passed through the main passage and passed through a bypass passage, and (3) a measurement region and a reference region are provided in the observation section of the chip for analysis. In the present invention, the aspects (1) to (3) can be achieved individually or two or more thereof can be combined.
摘要翻译： 本发明涉及一种用于光学分析的芯片。 特别地，本发明涉及一种处理液体样品的光学传感器，该液体样品是可用于选择性地测量生物相关物质或化学物质如环境污染物质或健康影响物质的分析用芯片 要测量的液体 本发明的光学分析用芯片的特征在于，（1）在用于分析的芯片的通路中，在样品导入部和观察部之间设置有吸附区域（滤波区域），（2）旁路通路 设置在用于分析的芯片的通道（主通道）中，并且在通过主通道并穿过旁路通道的样品之间产生时间延迟，并且（3）在观察中提供测量区域和参考区域 芯片部分进行分析。 在本发明中，方面（1）〜（3）可以单独实现，也可以组合2个以上。
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