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公开(公告)号：US20070148679A1
公开(公告)日：2007-06-28
申请号：US11637087
申请日：2006-12-12
申请人： Mie Ishii , Nobuko Yamamoto , Masahiro Kawaguchi , Tetsuo Okabe , Hiroki Sasaki , Satoshi Yajima , Yasuhiro Matsumura , Hisayuki Matsushita , Hiroyuki Tsunoda , Kunio Harada
发明人： Mie Ishii , Nobuko Yamamoto , Masahiro Kawaguchi , Tetsuo Okabe , Hiroki Sasaki , Satoshi Yajima , Yasuhiro Matsumura , Hisayuki Matsushita , Hiroyuki Tsunoda , Kunio Harada
CPC分类号： C12Q1/6886 , C12Q2600/158 , C12Q2600/16
摘要： Colon cancer cells in a sample are screened by analyzing the amount of expression of at least 2 or more genes or products thereof selected from the group of genes listed in Tables 1 and 30. As compared to conventional method, patients having colon cancer can be detected with higher accuracy.
摘要翻译： 通过分析选自表1和30中列出的基因组的至少2个或更多个基因或其产物的表达量来筛选样品中的结肠癌细胞。与常规方法相比，可以检测到具有结肠癌的患者 精度更高。
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2.发明申请Method for screening colon cancer cells and gene set used for examination of colon cancer 审中-公开筛选结肠癌细胞的方法和用于检查结肠癌的基因组公开(公告)号：US20090011413A1
公开(公告)日：2009-01-08
申请号：US11808943
申请日：2007-06-14
申请人： Mie Ishii , Nobuko Yamamoto , Masahiro Kawaguchi , Tetsuo Okabe , Hiroki Sasaki , Satoshi Yajima , Yasuhiro Matsumura , Hisayuki Matsushita , Hiroyuki Tsunoda , Kunio Harada
发明人： Mie Ishii , Nobuko Yamamoto , Masahiro Kawaguchi , Tetsuo Okabe , Hiroki Sasaki , Satoshi Yajima , Yasuhiro Matsumura , Hisayuki Matsushita , Hiroyuki Tsunoda , Kunio Harada
CPC分类号： C12Q1/6886 , C12Q2600/158 , C12Q2600/16
摘要： Colon cancer cells in a sample are screened by analyzing the amount of expression of at least 2 or more genes or products thereof selected from the group of genes listed in Tables 1 and 30. As compared to conventional method, patients having colon cancer can be detected with higher accuracy. Colon cancer cells in stool are also screened by analyzing expression of genes selected from the group of genes listed in Table 37.
摘要翻译： 通过分析选自表1和30中列出的基因组的至少2个或更多个基因或其产物的表达量来筛选样品中的结肠癌细胞。与常规方法相比，可以检测到具有结肠癌的患者 精度更高。 还通过分析表37所列基因的表达分析来筛选粪便中的结肠癌细胞。
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公开(公告)号：US20080145932A1
公开(公告)日：2008-06-19
申请号：US12030270
申请日：2008-02-13
IPC分类号： C12N5/06
CPC分类号： G01N33/574
摘要： A method and apparatus for recovering cells from stool are provided for diagnosing colorectal cancer from stool naturally voided by multiple specimens. The method includes the steps of preparing a sample of naturally voided and collected stool, to which sample a buffer solution is added, causing cancer cells in the sample from which the impurities have been removed to be adsorbed on a solid carrier, and recovering the cancer cells thus adsorbed.
摘要翻译： 提供了从粪便中回收细胞的方法和装置，用于从多个样品天然排除的粪便中诊断结肠直肠癌。 该方法包括以下步骤：制备天然排空和收集的粪便的样品，向其中添加缓冲溶液样品，使已经除去杂质的样品中的癌细胞吸附在固体载体上，并回收癌症 因此吸附细胞。
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公开(公告)号：US20060122534A1
公开(公告)日：2006-06-08
申请号：US11212575
申请日：2005-08-29
申请人： Yasuhiro Matsumura , Hisayuki Matsushita , Hiroyuki Tsunoda , Kunio Harada , Kazunori Okano , Keiichi Nagai
发明人： Yasuhiro Matsumura , Hisayuki Matsushita , Hiroyuki Tsunoda , Kunio Harada , Kazunori Okano , Keiichi Nagai
CPC分类号： A61B10/0038 , A61B10/0096
摘要： A container for the suspension and filtration of stool enables quick, simple, and safe collection of cancer cells separated in stool. The container comprises (a) a stool collection container 1, (c) a stool processing container main body 20, and (d) a pushing member 30. The stool collection container 1 comprises a syringe 2 capable of collecting 0.5 g or more of stool by being thrust into stool, a stool collecting opening, a handle 3 provided on the periphery of the syringe at the opposite end to the stool collecting opening, and a cap member 4 provided at the opposite end to the stool collecting opening. The stool processing container main body 20 comprises: a syringe storage portion 21 for storing the syringe; a suspension portion 22 connected to the syringe storage portion for suspending the stool; a filtrate receiving container 23 detachably connected to the suspension portion for receiving a filtrate of the stool that has been suspended and filtered; and a filter 26 provided at a connection portion between the suspension portion and the filtrate receiving container. The pushing member 30 is pressed to press or tear the cap member so as to move the stool collected in the syringe of the stool collection container into the suspension portion.
摘要翻译： 用于粪便悬浮和过滤的容器能够快速，简单和安全地收集在粪便中分离的癌细胞。 容器包括（a）粪便收集容器1，（c）粪便处理容器主体20，和（d）推动构件30。 粪便收集容器1包括注射器2，其能够通过推入粪便中收集0.5g或更多的粪便，粪便收集开口，在与粪便收集口相对的端部处设置在注射器的周边上的手柄3，以及 盖构件4设置在与粪便收集口相对的另一端。 粪便处理容器主体20包括：用于储存注射器的注射器存放部21; 连接到注射器存储部分用于悬挂粪便的悬挂部分22; 可拆卸地连接到悬挂部分的滤液接收容器23，用于接收已经悬浮和过滤的粪便滤液; 以及设置在悬架部分和滤液接收容器之间的连接部分处的过滤器26。 按压构件30被按压或撕开盖构件，以将收集在粪便收集容器的注射器中的粪便移动到悬挂部分中。
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公开(公告)号：US20050026230A1
公开(公告)日：2005-02-03
申请号：US10773316
申请日：2004-02-09
IPC分类号： C12M1/00 , C12N1/02 , C12N5/06 , C12N5/08 , G01N33/574
CPC分类号： G01N33/574
摘要： A method and apparatus for recovering cells from stool are provided for diagnosing colorectal cancer from stool naturally voided by multiple specimens. The method includes the steps of preparing a sample of naturally voided and collected stool, to which sample a buffer solution is added, causing cancer cells in the sample from which the impurities have been removed to be adsorbed on a solid carrier, and recovering the cancer cells thus adsorbed.
摘要翻译： 提供了从粪便中回收细胞的方法和装置，用于从多个样品天然排除的粪便中诊断结肠直肠癌。 该方法包括以下步骤：制备天然排空和收集的粪便的样品，向其中添加缓冲溶液样品，使已经除去杂质的样品中的癌细胞吸附在固体载体上，并回收癌症 因此吸附细胞。
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