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公开(公告)号:US12070495B2
公开(公告)日:2024-08-27
申请号:US17439198
申请日:2020-03-13
Applicant: ModernaTX, Inc. , The United States of America, as represented by the Department of Health and Human Services
Inventor: Paolo Lusso , Peng Zhang , Elisabeth Narayanan , Sayda Mahgoub Elbashir
CPC classification number: A61K39/21 , A61K39/39 , A61K2039/53 , A61K2039/55516 , A61K2039/6018
Abstract: Provided herein are methods and compositions for inducing in a subject abroad neutralizing antibody response to human immunodeficiency virus (HIV) infection.
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公开(公告)号:US20230303632A1
公开(公告)日:2023-09-28
申请号:US18176014
申请日:2023-02-28
Applicant: ModernaTX, Inc.
Inventor: Giuseppe Ciaramella , Sayda Mahgoub Elbashir
IPC: C07K14/005 , A61K9/00 , A61K9/51 , A61K39/25
CPC classification number: C07K14/005 , A61K9/0019 , A61K9/5123 , A61K39/25 , A61K2039/53
Abstract: Aspects of the disclosure relate to nucleic acid vaccines. The vaccines include at least one RNA polynucleotides having an open reading frame encoding at least one varicella zoster virus (VZV) antigen. Methods for preparing and using such vaccines are also described.
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公开(公告)号:US11364292B2
公开(公告)日:2022-06-21
申请号:US16898268
申请日:2020-06-10
Applicant: ModernaTX, Inc.
Inventor: Giuseppe Ciaramella , Eric Yi-Chun Huang , Kapil Bahl , Tal Zaks , Sunny Himansu , Sayda Mahgoub Elbashir
IPC: A61K39/12 , A61K48/00 , A61K9/14 , A61K9/00 , C07K16/28 , C07K14/005 , C07K16/10 , C07K14/18 , A61K47/10 , A61K47/18 , A61K47/22 , A61K47/28 , C12N7/00 , A61P31/12 , A61P31/14 , A61K9/51 , A61K39/00
Abstract: Aspects of the disclosure relate to nucleic acid vaccines. The vaccines include one or more RNA polynucleotides having an open reading frame encoding one or more Chikungunya antigen(s), one or more Zika virus antigens, and one or more Dengue antigens. Methods for preparing and using such vaccines are also described.
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公开(公告)号:US20200368344A1
公开(公告)日:2020-11-26
申请号:US16898268
申请日:2020-06-10
Applicant: ModernaTX, Inc.
Inventor: Giuseppe Ciaramella , Eric Yi-Chun Huang , Kapil Bahl , Tal Zaks , Sunny Himansu , Sayda Mahgoub Elbashir
IPC: A61K39/12 , A61K9/00 , C07K16/28 , C07K14/005 , C07K16/10 , A61K9/14 , A61K47/10 , A61K47/18 , A61K47/22 , A61K47/28 , C12N7/00 , A61P31/12 , A61P31/14 , A61K9/51
Abstract: Aspects of the disclosure relate to nucleic acid vaccines. The vaccines include one or more RNA polynucleotides having an open reading frame encoding one or more Chikungunya antigen(s), one or more Zika virus antigens, and one or more Dengue antigens. Methods for preparing and using such vaccines are also described.
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公开(公告)号:US20250073327A1
公开(公告)日:2025-03-06
申请号:US18771978
申请日:2024-07-12
Applicant: ModernaTX, Inc. , The United States of America, as represented by the Department of Health and Human Services
Inventor: Paolo Lusso , Peng Zhang , Elisabeth Narayanan , Sayda Mahgoub Elbashir
Abstract: Provided herein are methods and compositions for inducing in a subject a broad neutralizing antibody response to human immunodeficiency virus (HIV) infection.
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公开(公告)号:US11643441B1
公开(公告)日:2023-05-09
申请号:US15767587
申请日:2016-10-21
Applicant: ModernaTX, Inc.
Inventor: Giuseppe Ciaramella , Sayda Mahgoub Elbashir
IPC: C07K14/005 , A61K39/25 , A61K9/51 , A61K9/00 , A61K39/00
CPC classification number: C07K14/005 , A61K9/0019 , A61K9/5123 , A61K39/25 , A61K2039/53 , A61K2039/54 , A61K2039/545 , A61K2039/575 , A61K2039/70 , C12N2710/16722 , C12N2710/16734 , C12N2710/16771
Abstract: Aspects of the disclosure relate to nucleic acid vaccines. The vaccines include at least one RNA polynucleotides having an open reading frame encoding at least one varicella zoster virus (VZV) antigen. Methods for preparing and using such vaccines are also described.
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公开(公告)号:US20230374079A1
公开(公告)日:2023-11-23
申请号:US18365948
申请日:2023-08-04
Applicant: ModernaTX, Inc.
Inventor: Giuseppe Ciaramella , Sayda Mahgoub Elbashir
IPC: C07K14/005 , A61K9/51 , A61K39/25 , A61K9/00
CPC classification number: C07K14/005 , A61K9/5123 , A61K39/25 , A61K9/0019 , A61K2039/70
Abstract: Aspects of the disclosure relate to nucleic acid vaccines. The vaccines include at least one RNA polynucleotides having an open reading frame encoding at least one varicella zoster virus (VZV) antigen. Methods for preparing and using such vaccines are also described.
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公开(公告)号:US20230338506A1
公开(公告)日:2023-10-26
申请号:US17796401
申请日:2021-01-29
Applicant: ModernaTX, Inc.
Inventor: Christine Shaw , Guillaume Stewart-Jones , Elisabeth Narayanan , Vladimir Presnyak , Sayda Mahgoub Elbashir
IPC: A61K39/275 , A61K9/127 , C12N15/86 , A61K39/155 , A61P31/14 , C07K14/005
CPC classification number: A61K39/155 , A61K9/1271 , A61K39/275 , A61P31/14 , C07K14/005 , C12N15/86 , A61K2039/53
Abstract: The disclosure relates to respiratory virus ribonucleic acid (RNA) vaccines as well as methods of using the vaccines and compositions comprising the vaccines.
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公开(公告)号:US20200289639A1
公开(公告)日:2020-09-17
申请号:US16853973
申请日:2020-04-21
Applicant: ModernaTX, Inc.
Inventor: Giuseppe Ciaramella , Sunny Himansu , Eric Yi-Chun Huang , Tal Zaks , Sayda Mahgoub Elbashir
IPC: A61K39/12 , A61K9/00 , A61K9/127 , A61K9/51 , A61K39/015 , A61P11/00 , A61K39/39 , A61K39/42 , A61K48/00
Abstract: The disclosure relates to tropical diseases such as viral mosquito borne illnesses and the treatment thereof. The invention includes ribonucleic acid vaccines and combination vaccines, as well as methods of using the vaccines and compositions comprising the vaccines for treating and preventing tropical disease.
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公开(公告)号:US10675342B2
公开(公告)日:2020-06-09
申请号:US16136503
申请日:2018-09-20
Applicant: ModernaTX, Inc.
Inventor: Giuseppe Ciaramella , Sunny Himansu , Eric Yi-Chun Huang , Tal Zaks , Sayda Mahgoub Elbashir
IPC: A61K39/12 , A61K39/015 , A61K39/39 , A61K9/00 , A61K9/127 , A61K9/51 , A61P11/00 , A61K39/42 , A61K48/00 , A61K39/00
Abstract: The disclosure relates to tropical diseases such as viral mosquito borne illnesses and the treatment thereof. The invention includes ribonucleic acid vaccines and combination vaccines, as well as methods of using the vaccines and compositions comprising the vaccines for treating and preventing tropical disease.
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