公开(公告)号：US09976139B2

公开(公告)日：2018-05-22

申请号：US14664659

申请日：2015-03-20

Applicant: MONSANTO TECHNOLOGY LLC

Inventor： Shihshieh Huang ,  Thomas M. Malvar ,  Michael H. Luethy

IPC: C12N15/113 ,  C12N15/82 ,  C07H21/02 ,  C12N9/06 ,  C12N15/11 ,  A61K48/00

CPC classification number: C12N15/113 ,  A61K48/00 ,  C07H21/02 ,  C12N9/0028 ,  C12N15/111 ,  C12N15/8218 ,  C12N15/8251 ,  C12N15/8254 ,  C12N2310/11 ,  C12N2310/111 ,  C12N2310/14 ,  C12N2310/53 ,  C12N2330/30

Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct which comprises in 5′ to 3′ order a promoter element operably linked to an anti-sense-oriented DNA element and a complementary DNA element.

公开(公告)号：US09119408B2

公开(公告)日：2015-09-01

申请号：US13914505

申请日：2013-06-10

Applicant: Monsanto Technology LLC

Inventor： Michael H. Luethy ,  Thomas M. Malvar ,  Shihshieh Huang

IPC: C12N15/82 ,  A01H1/00 ,  A23K1/14 ,  C07K14/415 ,  C12N9/06 ,  A23L1/10

Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct that comprises in 5′ to 3′ order a promoter element operably linked to more than one anti-sense-oriented DNA element and one or more complementary DNA elements.

公开(公告)号：US20180263205A1

公开(公告)日：2018-09-20

申请号：US15917489

申请日：2018-03-09

Applicant: MONSANTO TECHNOLOGY LLC

Inventor： Michael H. Luethy ,  Thomas M. Malvar ,  Shihshieh Huang

IPC: A01H5/10 ,  A23K10/30 ,  A23L7/10 ,  C12N15/82 ,  C12N9/06 ,  C07K14/415

Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct that comprises in 5′ to 3′ order a promoter element operably linked to more than one anti-sense-oriented DNA element and one or more complementary DNA elements.

公开(公告)号：US09913487B2

公开(公告)日：2018-03-13

申请号：US13914505

申请日：2013-06-10

Applicant: Monsanto Technology LLC

Inventor： Michael H. Luethy ,  Thomas M. Malvar ,  Shihshieh Huang

IPC: A23K1/14 ,  C07K14/415 ,  C12N9/06 ,  C12N15/82 ,  A23K10/30 ,  A23L7/10

CPC classification number: A01H5/10 ,  A23K10/30 ,  A23L7/198 ,  C07K14/415 ,  C12N9/0028 ,  C12N15/8218 ,  C12N15/8247 ,  C12N15/8251 ,  C12N15/8254

Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct that comprises in 5′ to 3′ order a promoter element operably linked to more than one anti-sense-oriented DNA element and one or more complementary DNA elements.

公开(公告)号：US10772276B2

公开(公告)日：2020-09-15

申请号：US15917489

申请日：2018-03-09

Applicant: MONSANTO TECHNOLOGY LLC

Inventor： Michael H. Luethy ,  Thomas M. Malvar ,  Shihshieh Huang

IPC: A01H5/10 ,  A23L7/10 ,  A23K10/30 ,  C07K14/415 ,  C12N9/06 ,  C12N15/82

Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct that comprises in 5′ to 3′ order a promoter element operably linked to more than one anti-sense-oriented DNA element and one or more complementary DNA elements.

公开(公告)号：US20150191728A1

公开(公告)日：2015-07-09

申请号：US14664659

申请日：2015-03-20

Applicant: Monsanto Technology LLC

Inventor： Shihshieh Huang ,  Thomas M. Malvar ,  Michael H. Luethy

IPC: C12N15/113

CPC classification number: C12N15/113 ,  A61K48/00 ,  C07H21/02 ,  C12N9/0028 ,  C12N15/111 ,  C12N15/8218 ,  C12N15/8251 ,  C12N15/8254 ,  C12N2310/11 ,  C12N2310/111 ,  C12N2310/14 ,  C12N2310/53 ,  C12N2330/30

Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct which comprises in 5′ to 3′ order a promoter element operably linked to an anti-sense-oriented DNA element and a complementary DNA element.

Abstract translation: 在转基因生物体的细胞中产生以反义取向RNA环形式的反义RNA RNA基因抑制剂。 植物，通过从重组DNA构建体转录，其以5'至3'的顺序包含可操作地连接到反义取向DNA元件和互补DNA元件的启动子元件。

公开(公告)号：US20180007856A9

公开(公告)日：2018-01-11

申请号：US13914505

申请日：2013-06-10

Applicant: Monsanto Technology LLC

Inventor： Michael H. Luethy ,  Thomas M. Malvar ,  Shihshieh Huang

IPC: A01H5/10 ,  C12N9/06 ,  C07K14/415 ,  C12N15/82

CPC classification number: A01H5/10 ,  A23K10/30 ,  A23L7/198 ,  C07K14/415 ,  C12N9/0028 ,  C12N15/8218 ,  C12N15/8247 ,  C12N15/8251 ,  C12N15/8254

Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct that comprises in 5′ to 3′ order a promoter element operably linked to more than one anti-sense-oriented DNA element and one or more complementary DNA elements.

公开(公告)号：US20140173778A1

公开(公告)日：2014-06-19

申请号：US13914505

申请日：2013-06-10

Applicant: Monsanto Technology LLC

Inventor： Michael H. Luethy ,  Thomas M. Malvar ,  Shihshieh Huang

IPC: C12N15/82 ,  A23L1/10 ,  A23K1/14

CPC classification number: A01H5/10 ,  A23K10/30 ,  A23L7/198 ,  C07K14/415 ,  C12N9/0028 ,  C12N15/8218 ,  C12N15/8247 ,  C12N15/8251 ,  C12N15/8254

Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct that comprises in 5′ to 3′ order a promoter element operably linked to more than one anti-sense-oriented DNA element and one or more complementary DNA elements.

Abstract translation: 在转基因生物体的细胞中产生以反义取向RNA环形式的反义RNA RNA基因抑制剂。 植物通过从包含5'至3'顺序的重组DNA构建体转录起可操作地连接到多于一个反义取向DNA元件和一个或多个互补DNA元件的启动子元件。