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公开(公告)号：US08834852B2
公开(公告)日：2014-09-16
申请号：US12772492
申请日：2010-05-03
IPC分类号： A61K8/00 , A61K8/18 , A61Q11/00 , A01N43/04 , A61K31/70 , A61Q17/00 , A61K8/60 , A61K8/34 , A61K8/39 , A61K8/73 , A61K31/7028 , A61K31/7032
CPC分类号： A61Q17/005 , A61K8/34 , A61K8/39 , A61K8/602 , A61K8/604 , A61K8/608 , A61K8/73 , A61K31/7028 , A61K31/7032 , A61Q11/00
摘要： The present invention relates to an oral care composition, which contains a compound represented by the formula (A): (wherein, R represents a substituted or unsubstituted, linear or branched alkyl group having from 6 to 18 carbon atoms, G represents a galactose residue, m stands for an integer of from 0 to 200, and n stands for an integer of from 1 to 30); and a coaggregation inhibitor of bacteria of the genus Fusobacterium and cariogenic bacteria, which contains the compound as an effective ingredient. The composition for oral cavity according to the present invention inhibits coaggregation of bacteria of the genus Fusobacterium with cariogenic bacteria so that it has an excellent caries preventive effect.
摘要翻译： 本发明涉及一种口腔护理组合物，其含有式（A）表示的化合物：（其中，R表示具有6至18个碳原子的取代或未取代的直链或支链烷基，G表示半乳糖残基 m表示0〜200的整数，n表示1〜30的整数）表示。 以及含有该化合物作为有效成分的Fusobacterium属和致龋细菌属细菌的共聚抑制剂。 根据本发明的口腔用组合物抑制Fusobacterium属细菌与致龋细菌的共聚，使其具有优异的防龋效果。
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公开(公告)号：US20080255058A1
公开(公告)日：2008-10-16
申请号：US11576114
申请日：2005-09-28
IPC分类号： A61K31/7028 , C07H15/04
CPC分类号： A61Q17/005 , A61K8/34 , A61K8/39 , A61K8/602 , A61K8/604 , A61K8/608 , A61K8/73 , A61K31/7028 , A61K31/7032 , A61Q11/00
摘要： The present invention relates to an oral care composition, which contains a compound represented by the formula (A): (wherein, R represents a substituted or unsubstituted, linear or branched alkyl group having from 6 to 18 carbon atoms, G represents a galactose residue, m stands for an integer of from 0 to 200, and n stands for an integer of from 1 to 30); and a coaggregation inhibitor of bacteria of the genus Fusobacterium and cariogenic bacteria, which contains the compound as an effective ingredient. The composition for oral cavity according to the present invention inhibits coaggregation of bacteria of the genus Fusobacterium with cariogenic bacteria so that it has an excellent caries preventive effect.
摘要翻译： 本发明涉及一种口腔护理组合物，其含有式（A）表示的化合物：（其中，R表示具有6至18个碳原子的取代或未取代的直链或支链烷基，G表示半乳糖残基 m表示0〜200的整数，n表示1〜30的整数）表示。 以及含有该化合物作为有效成分的Fusobacterium属和致龋细菌属细菌的共聚抑制剂。 根据本发明的口腔用组合物抑制Fusobacterium属细菌与致龋细菌的共聚，使其具有优异的防龋效果。
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公开(公告)号：US20090156511A1
公开(公告)日：2009-06-18
申请号：US11885387
申请日：2006-02-27
申请人： Katsuya Ueno , Hiromoto Mizushima , Hiromi Kubota , Katsumi Endo
发明人： Katsuya Ueno , Hiromoto Mizushima , Hiromi Kubota , Katsumi Endo
IPC分类号： A61K31/7004 , A61P43/00
CPC分类号： A61K31/7004 , A61K8/602 , A61Q19/005
摘要： The present invention relates to a preservative efficacy-enhancing agent capable of allowing an antiseptic agent to exhibit a high preservative efficacy even when the antiseptic agent is used at a low concentration; a preservative efficacy-enhancing composition containing the same; and a method for enhancing a preservative efficacy of antiseptic agents. The present invention relates to: (1) a preservative efficacy-enhancing agent for antiseptic agents which includes an amphiphilic galactose derivative (A) as an effective ingredient; (2) a preservative efficacy-enhancing composition including 0.01 to 30% by mass of an amphiphilic galactose derivative (A) and 0.01 to 1.0% by mass of an antiseptic agent (B); and (3) a method for enhancing a preservative efficacy of an antiseptic composition which includes the step of allowing 0.01 to 30% by mass of an amphiphilic galactose derivative (A) to coexist with an antiseptic agent (B) in the composition.
摘要翻译： 本发明涉及一种防腐剂功效增强剂，即使在低浓度使用防腐剂时，也能够使防腐剂表现出高的防腐效果; 含有该组合物的防腐效能增强组合物; 以及提高防腐剂的防腐效果的方法。 本发明涉及：（1）防腐剂的防腐功效增强剂，其包含两亲性半乳糖衍生物（A）作为有效成分; （2）含有0.01〜30质量％的两亲性半乳糖衍生物（A）和0.01〜1.0质量％的防腐剂（B）的防腐效能增强组合物。 （3）提高防腐剂组合物的防腐功效的方法，其包括使0.01〜30质量％的两亲半乳糖衍生物（A）与组合物中的防腐剂（B）共存的步骤。
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公开(公告)号：US08673865B2
公开(公告)日：2014-03-18
申请号：US11885387
申请日：2006-02-27
申请人： Katsuya Ueno , Hiromoto Mizushima , Hiromi Kubota , Katsumi Endo
发明人： Katsuya Ueno , Hiromoto Mizushima , Hiromi Kubota , Katsumi Endo
CPC分类号： A61K31/7004 , A61K8/602 , A61Q19/005
摘要： The present invention relates to a preservative efficacy-enhancing agent capable of allowing an antiseptic agent to exhibit a high preservative efficacy even when the antiseptic agent is used at a low concentration; a preservative efficacy-enhancing composition containing the same; and a method for enhancing a preservative efficacy of antiseptic agents. The present invention relates to: (1) a preservative efficacy-enhancing agent for antiseptic agents which includes an amphiphilic galactose derivative (A) as an effective ingredient; (2) a preservative efficacy-enhancing composition including 0.01 to 30% by mass of an amphiphilic galactose derivative (A) and 0.01 to 1.0% by mass of an antiseptic agent (B); and (3) a method for enhancing a preservative efficacy of an antiseptic composition which includes the step of allowing 0.01 to 30% by mass of an amphiphilic galactose derivative (A) to coexist with an antiseptic agent (B) in the composition.
摘要翻译： 本发明涉及一种防腐剂功效增强剂，即使在低浓度使用防腐剂时，也能够使防腐剂表现出高的防腐效果; 含有该组合物的防腐效能增强组合物; 以及提高防腐剂的防腐效果的方法。 本发明涉及：（1）防腐剂的防腐功效增强剂，其包含两亲性半乳糖衍生物（A）作为有效成分; （2）含有0.01〜30质量％的两亲性半乳糖衍生物（A）和0.01〜1.0质量％的防腐剂（B）的防腐效能增强组合物。 （3）提高防腐剂组合物的防腐功效的方法，其包括使0.01〜30质量％的两亲半乳糖衍生物（A）与组合物中的防腐剂（B）共存的步骤。
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公开(公告)号：US07351809B2
公开(公告)日：2008-04-01
申请号：US10574549
申请日：2004-10-01
申请人： Katsuya Ueno , Hiromoto Mizushima
发明人： Katsuya Ueno , Hiromoto Mizushima
摘要： A process is provided for the selective and convenient production of a glycerol glycoside, which has been glycosidated at the 1-hydroxyl group of glycerol and is useful as a glyceroglycolipid precursor, humectant or the like.A glycerol carbonate glycoside represented by the following formula (1): wherein G represents a monosaccharide residue, and n stands for an integer of from 1 to 3; a process for producing the glycerol carbonate glycoside of formula (1) by reacting a saccharide with glycerol-1,2-carbonate in the presence of an acid; and a process for producing a glycerol glycoside which is represented by the following formula (2): wherein G and n have the same meanings as defined above, by deprotecting the glycerol carbonate glycoside represented by formula (1).
摘要翻译： 提供了选择性和方便地制备甘油糖苷的方法，甘油糖苷已经在甘油的1-羟基上被糖苷化，并且可用作甘油糖脂前体，保湿剂等。 由下式（1）表示的甘油碳酸酯糖苷：其中G表示单糖残基，n表示1〜3的整数， 通过在酸的存在下使糖与甘油-1,2-碳酸酯反应制备式（1）的甘油碳酸酯糖苷的方法; 以及由式（2）表示的甘油糖苷的制造方法，其中G和n具有与上述相同的含义，通过使由式（1）表示的甘油碳酸酯糖苷脱保护。
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6.发明授权公开(公告)号：US07582713B2
公开(公告)日：2009-09-01
申请号：US11030295
申请日：2005-01-07
申请人： Ichiro Terada , Satoru Hommura , Nobuyuki Kasahara , Katsuya Ueno
发明人： Ichiro Terada , Satoru Hommura , Nobuyuki Kasahara , Katsuya Ueno
IPC分类号： C08F12/30
CPC分类号： C08J5/2293 , C08F30/04 , C08F130/04 , C08F230/04 , C08J3/05 , C08J5/20 , C08J2327/12 , C08J2327/18 , H01M4/8605 , H01M4/8803 , H01M4/8828 , H01M4/921 , H01M4/96 , H01M8/1004 , H01M8/1023 , H01M8/1039 , H01M8/1051 , H01M8/1081 , Y02P70/56 , Y10T428/24802
摘要： A thickened ion exchange polymer dispersion is obtained by applying ultrasonic vibration or a shearing force to an ion exchange polymer dispersion having a fluorinated polymer having sulfonic acid groups as an ion exchange polymer uniformly dispersed in a dispersion medium so that the viscosity of the dispersion at 25° C. at a shear rate of 10 (1/s) increases 2-2000 times in a thickening step. When formed into a membrane, the dispersion can forms an ion exchange membrane having a uniform and small thickness, high strength, which is free from cracking and shows constant swelling in water and steam. Further, a layer formed by applying a coating solution containing this dispersion and a catalyst powder comprising catalyst metal particles and a carbon support loaded with the catalyst metal particles to a substrate can be used to prepare a membrane-electrode assembly as a catalyst layer for at least one of the cathode and the anode by providing the catalyst layer adjacently to an ion exchange membrane. Because the catalyst layer is highly strong, has few defects and is excellently smooth, a high-performance membrane-electrode assembly for solid polymer electrolyte fuel cells can be obtained.
摘要翻译： 通过对具有磺酸基的氟化聚合物作为离子交换聚合物均匀分散在分散介质中的离子交换聚合物分散体施加超声波振动或剪切力，使得分散体在25℃下的粘度 在10（1 / s）的剪切速率下，在增稠步骤中增加2-2000次。 当形成膜时，分散体可以形成具有均匀且小的厚度，高强度的离子交换膜，其没有破裂并且在水和蒸汽中显示恒定的溶胀。 此外，可以使用通过将含有该分散体的涂布溶液和包含催化剂金属颗粒的催化剂粉末和负载有催化剂金属颗粒的碳载体的催化剂粉末涂布到基板上而形成的层，以制备作为催化剂层的膜 - 电极组件 通过相对于离子交换膜提供催化剂层，阴极和阳极中的至少一个。 由于催化剂层强度高，缺点少，光滑性好，因此可以得到固体高分子电解质燃料电池用高性能膜 - 电极组件。
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公开(公告)号：US20070213517A1
公开(公告)日：2007-09-13
申请号：US10574549
申请日：2004-10-01
申请人： Katsuya Ueno , Hirozumi Mizushima
发明人： Katsuya Ueno , Hirozumi Mizushima
摘要： A process is provided for the selective and convenient production of a glycerol glycoside, which has been glycosidated at the 1-hydroxyl group of glycerol and is useful as a glyceroglycolipid precursor, humectant or the like. A glycerol carbonate glycoside represented by the following formula (1): wherein G represents a monosaccharide residue, and n stands for an integer of from 1 to 3; a process for producing the glycerol carbonate glycoside of formula (1) by reacting a saccharide with glycerol-1,2-carbonate in the presence of an acid; and a process for producing a glycerol glycoside which is represented by the following formula (2): wherein G and n have the same meanings as defined above, by deprotecting the glycerol carbonate glycoside represented by formula (1).
摘要翻译： 提供了选择性和方便地制备甘油糖苷的方法，甘油糖苷已经在甘油的1-羟基上被糖苷化，并且可用作甘油糖脂前体，保湿剂等。 由下式（1）表示的甘油碳酸酯糖苷：其中G表示单糖残基，n表示1〜3的整数， 通过在酸的存在下使糖与甘油-1,2-碳酸酯反应制备式（1）的甘油碳酸酯糖苷的方法; 以及由式（2）表示的甘油糖苷的制造方法，其中G和n具有与上述相同的含义，通过使由式（1）表示的甘油碳酸酯糖苷脱保护。
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8.发明申请Process for producing electrolyte material for polymer electrolyte fuel cells, and membrane-electrode assembly for polymer electrolyte fuel cells 有权用于生产用于聚合物电解质燃料电池的电解质材料的方法和用于聚合物电解质燃料电池的膜 - 电极组件公开(公告)号：US20060287497A1
公开(公告)日：2006-12-21
申请号：US11183748
申请日：2005-07-19
CPC分类号： C08J5/225 , C08F8/12 , C08F2800/10 , C08F2800/20 , C08J2327/12 , H01M8/1004 , H01M8/1023 , H01M8/1039 , Y02P70/56 , C08F234/02 , C08F216/1408 , C08F214/26 , C08F224/00
摘要： A membrane-electrode assembly for polymer electrolyte fuel cells which is excellent in water repellency and gas diffusivity and which exhibits a high output power density, can be obtained by using, as an electrolyte material for polymer electrolyte fuel cells, a fluoropolymer obtained by contacting a fluoropolymer which is excellent in gas diffusivity and which has alicyclic structures in its main chain and further has sulfonic acid groups, with fluorine gas for fluorination to increase water repellency and stabilize the molecule ends. The above fluoropolymer is preferably made of a copolymer comprising repeating units based on the following monomer A and repeating units based on the following monomer B (wherein Y is a fluorine atom or a trifluoromethyl group, m is an integer of from 0 to 3, p is 0 or 1, and n is an integer of from 1 to 12): Monomer A: A perfluoromonomer which gives a polymer having repeating units containing cyclic structures in its main chain by radical polymerization Monomer B: CF2═CF—(OCF2CFY)m—Op—(CF2)n—SO3H
摘要翻译： 作为聚合物电解质型燃料电池的电解质材料，可以通过使用通过使聚合物电解质燃料电池接触而获得的含氟聚合物，获得具有优异的防水性和气体扩散性并且显示出高功率密度的聚合物电解质燃料电池用膜电极组件 含氟聚合物，其气体扩散性优异，并且在其主链中具有脂环结构并且还具有磺酸基，氟气用于氟化以增加拒水性并稳定分子末端。 上述含氟聚合物优选由包含以下单体A的重复单元和基于以下单体B的重复单元（其中Y为氟原子或三氟甲基，m为0〜3的整数，p 是0或1，n是1至12的整数）：单体A：通过自由基聚合在其主链中产生具有含有环状结构的重复单元的聚合物的全氟单体单体B：CF 2 -CF-（OCF 2 C 1 -CY）m -O - - - （CF 2 N）n 3 H 3
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公开(公告)号：US07767309B2
公开(公告)日：2010-08-03
申请号：US12511215
申请日：2009-07-29
申请人： Katsuya Ueno , Yasuhide Kawaguchi
发明人： Katsuya Ueno , Yasuhide Kawaguchi
CPC分类号： B29C33/62 , B82Y10/00 , B82Y40/00 , G03F7/0002 , Y10T428/31663
摘要： To provide an imprinting mold, of which a coating layer formed on its surface is hardly susceptible to peeling, and a process for its production.An imprinting mold comprising a mold body and a coating layer made of a release agent, formed on the surface of the mold body, wherein the release agent contains a compound of the following formula (1), and a process for its production: wherein R is Rf—X—, both R are the same group, Rf is a perfluoroalkyl group, X is at least one member selected from —(OC3F6)—, —(OC2F4)— and —(OCF2)—, provided that the sum of such units is at least 1, Y is an organic group, is an average of n is from 2 to 10, Z is —Si(R1)m(R2)3-m, R1 is a hydroxyl group or a hydrolysable group, R2 is a hydrogen atom or a hydrocarbon group, and m is from 1 to 3.
摘要翻译： 为了提供一种在其表面上形成的涂层几乎不易剥离的压印模及其制造方法。 一种压印模具，包括模具体和由脱模剂制成的涂层，其形成在模具体的表面上，其中脱模剂含有下式（1）的化合物及其制备方法：其中R 是Rf-X-，两个R是相同的基团，Rf是全氟烷基，X是至少一个选自 - （OC 3 F 6） - ， - （OC 2 F 4） - 和 - （OCF 2） - ，条件是 这些单元至少为1，Y为有机基团，n为2〜10的平均值，Z为-Si（R1）m（R2）3-m，R1为羟基或可水解基团，R2 是氢原子或烃基，m为1〜3。
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公开(公告)号：US08759567B2
公开(公告)日：2014-06-24
申请号：US13248732
申请日：2011-09-29
申请人： Katsuya Ueno , Toshiyuki Tanaka , Mayako Takahashi , Kazuhiko Yamada , Fusaaki Takeo , Shoji Furuta
发明人： Katsuya Ueno , Toshiyuki Tanaka , Mayako Takahashi , Kazuhiko Yamada , Fusaaki Takeo , Shoji Furuta
IPC分类号： C07C331/00 , C07C381/00 , C07C21/18 , C07C17/00
CPC分类号： C07C407/00 , C07C409/34
摘要： To provide a process for safely producing a perfluoroacyl peroxide with good productivity.By supplying a perfluoroacyl halide-containing organic solvent solution, an aqueous solution of hydrogen peroxide or a metal peroxide, and an aqueous basic alkali metal compound solution to a tubular reactor to allow them to react with one another, in a flow rate ratio of, as represented by molar ratio of the compounds in the solutions, from 1.00 to 1.35 of the basic alkali metal compound and from 0.60 to 40 of hydrogen peroxide or the metal peroxide per 1 of the perfluoroacyl halide, the yield of a perfluoroacyl peroxide based on the material perfluoroacyl halide can be remarkably improved as compared with conventional technique.
摘要翻译： 提供以高生产率安全生产全氟酰基过氧化物的方法。 通过向管状反应器中供给含全氟酰卤的有机溶剂溶液，过氧化氢水溶液或金属过氧化物水溶液和碱式碱金属化合物水溶液，以使其彼此反应， 如溶液中的化合物的摩尔比，碱金属碱金属化合物的1.00至1.35，每1全氟酰卤的0.60至40的过氧化氢或金属过氧化物所表示的，全氟酰基过氧化物的产率基于 与常规技术相比，全氟酰卤的材料可以显着提高。
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