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    Lactobacillus Reuteri DSM 17938 for the Development of Cognitive Function
    5.
    发明申请
    Lactobacillus Reuteri DSM 17938 for the Development of Cognitive Function 审中-公开
    Luterobacillus Reuteri DSM 17938用于认知功能的发展

    公开(公告)号：US20140363410A1

    公开(公告)日：2014-12-11

    申请号：US14369297

    申请日：2012-11-30

    申请人： NESTEC S.A.

    发明人： Gabriela Bergonzelli Degonda ,  Magali Faure ,  Nicole Kusy

    IPC分类号： A61K35/74 ,  A23L1/30

    CPC分类号： A61K35/74 ,  A23L33/135 ,  A23L33/40 ,  A23V2002/00 ,  A23Y2220/71 ,  A61K35/747 ,  A61K2035/115 ,  A23V2200/322

    摘要： The invention relates to Lactobacillus reuteri DSM 17938 for promoting the establishment of healthy and normal cognitive function in young mammals. In particular, the invention relates to the use of Lactobacillus reuteri DSM 17938 for promoting development of the brain structures responsible for cognitive functions (e.g. cortex and hippocampus) and its associated neural pathways and/or to reverse retardation and/or to prevent retardation of the establishment of cognitive functions. Humans or animals and, in particular, a foetus, pre-term or term born infant, toddler or child or a young adult may benefit from the invention.

    摘要翻译： 本发明涉及用于促进在年轻哺乳动物中建立健康和正常认知功能的罗伊氏乳杆菌DSM 17938。 特别地，本发明涉及使用罗伊氏乳杆菌DSM 17938来促进负责认知功能（例如皮层和海马）及其相关神经通路的脑结构的发展和/或反向延迟和/或阻止延迟 建立认知功能。 人类或动物，特别是胎儿，前期或术语出生的婴儿，幼儿或儿童或年轻成年人可受益于本发明。

    Lactobacillus Reuteri DSM 17938 for the Development of the Enteric Nervous System
    6.
    发明申请
    Lactobacillus Reuteri DSM 17938 for the Development of the Enteric Nervous System 审中-公开
    罗氏乳杆菌DSM 17938用于肠内神经系统的发展

    公开(公告)号：US20140363409A1

    公开(公告)日：2014-12-11

    申请号：US14369277

    申请日：2012-11-30

    申请人： NESTEC S.A.

    发明人： Gabriela Bergonzelli Degonda ,  Magali Faure ,  Nicole Kusy

    IPC分类号： A61K35/74 ,  A23L1/30 ,  A23L1/29 ,  A61K45/06

    CPC分类号： A61K35/742 ,  A23L33/135 ,  A23L33/40 ,  A23V2002/00 ,  A23Y2220/71 ,  A61K35/747 ,  A61K45/06 ,  A61K2035/115

    摘要： The invention relates to Lactobacillus reuteri DSM 17938, and compositions comprising Lactobacillus reuteri DSM 17938, for promoting the healthy development and/or repair of the enteric nervous system in mammals. Humans or animals and, in particular, a foetus, pre-term or term-born infant, toddler or child may benefit from the invention. The invention may be especially beneficial to those infants having experienced IUGR, or having a low, or very low birth weight, and/or suffered from enteric nervous system growth retardation either in utero or, during or after birth. The administration of to Lactobacillus reuteri DSM 17938 promotes normal and healthy neuronal and glial development. It also ensures healthy neuronal differentiation in the peripheral nervous system.

    摘要翻译： 本发明涉及罗伊氏乳杆菌DSM 17938，以及包含罗伊氏乳杆菌DSM 17938的组合物，用于促进哺乳动物的肠神经系统的健康发育和/或修复。 人类或动物，特别是胎儿，早产或出生婴儿，幼儿或小孩可受益于本发明。 本发明对于经历IUGR或具有低或非常低出生体重的婴儿和/或在子宫内或出生期间或之后遭受肠神经系统生长迟缓的婴儿可能特别有益。 对罗伊氏乳杆菌DSM 17938的施用促进正常和健康的神经元和神经胶质细胞发育。 它也确保周围神经系统的健康神经元分化。

    Method of using bifidobacterium longum to treat depressive symptoms
    8.
    发明授权
    Method of using bifidobacterium longum to treat depressive symptoms 有权

    公开(公告)号：US10821139B2

    公开(公告)日：2020-11-03

    申请号：US15754734

    申请日：2016-08-31

    申请人： NESTEC S.A.

    发明人： Gabriela Bergonzelli Degonda ,  Tiago Alves Nunes ,  Valerie Marquardt ,  Jeroen Antonius Johannes Schmitt

    IPC分类号： A61K35/745 ,  A23L33/135 ,  A61P25/24

    摘要： Compositions and methods use Bifidobacterium longum NCC3001 (ATCC BAA-999) to treat or prevent a depressive symptom. Prolonged anti-depressive effects can continue after administration of the compositions is ended. Non-limiting examples of a depressive symptom which can be treated or prevented include depressed mood; sadness; anxiety; “empty” feelings; loss of interest or pleasure; irritability; restlessness; changes in appetite or weight; sleep disturbances; lack of or decreased energy; feelings of worthlessness; guilt; helplessness; anger and hostility; difficulty in thinking, concentrating, or making decisions; hopelessness; tiredness; fatigue; memory difficulties; tearfulness; brooding; phobias; excessive worry over physical health; sexual dysfunction; persistent physical symptoms that do not respond to treatment; and combinations thereof. These depressive symptoms can be associated with a depressive state or depressive disorder or can be found sub-clinically or not associated with these depressive states/disorders (e.g., not part of a syndrome or psychiatric disorder).