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公开(公告)号:US11346761B2
公开(公告)日:2022-05-31
申请号:US16076265
申请日:2017-02-07
申请人: NEW YORK UNIVERSITY
发明人: David G. Grier , Michael D. Ward , Xiao Zhong , Chen Wang , Laura A. Philips , David B. Ruffner , Fook Chiong Cheong
摘要: Systems and methods for holographic characterization of protein aggregates. Size and refractive index of individual aggregates in a solution can be determined. Information regarding morphology and porosity can be extracted from holographic data.
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公开(公告)号:US11085864B2
公开(公告)日:2021-08-10
申请号:US15526287
申请日:2015-11-11
申请人: NEW YORK UNIVERSITY
发明人: David G. Grier , David B. Ruffner , Aaron Yevick , Mark Hannel
摘要: Systems and methods for uniquely identifying fluid-phase products by endowing them with fingerprints composed of dispersed colloidal particles, and by reading out those fingerprints on demand using Total Holographic Characterization. A library of chemically inert colloidal particles is developed that can be dispersed into soft materials, the stoichiometry of the mixture encoding user-specified information, including information about the host material. Encoded information then can be recovered by high-speed analysis of holographic microscopy images of the dispersed particles. Specifically, holograms of individual colloidal spheres are analyzed with predictions of the theory of light scattering to measure each sphere's radius and refractive index, thereby building up the distribution of particle properties one particle at a time. A complete analysis of a colloidal fingerprint requires several thousand single-particle holograms and can be completed in ten minutes.
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公开(公告)号:US20210364403A1
公开(公告)日:2021-11-25
申请号:US17396980
申请日:2021-08-09
申请人: NEW YORK UNIVERSITY
发明人: David G. Grier , David B. Ruffner , Aaron Yevick , Mark Hannel
摘要: Systems and methods for uniquely identifying fluid-phase products by endowing them with fingerprints composed of dispersed colloidal particles, and by reading out those fingerprints on demand using Total Holographic Characterization. A library of chemically inert colloidal particles is developed that can be dispersed into soft materials, the stoichiometry of the mixture encoding user-specified information, including information about the host material. Encoded information then can be recovered by high-speed analysis of holographic microscopy images of the dispersed particles. Specifically, holograms of individual colloidal spheres are analyzed with predictions of the theory of light scattering to measure each sphere's radius and refractive index, thereby building up the distribution of particle properties one particle at a time. A complete analysis of a colloidal fingerprint requires several thousand single-particle holograms and can be completed in ten minutes.
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公开(公告)号:US10656065B2
公开(公告)日:2020-05-19
申请号:US15526287
申请日:2015-11-11
申请人: NEW YORK UNIVERSITY
发明人: David G. Grier , David B. Ruffner , Aaron Yevick , Mark Hannel
摘要: Systems and methods for uniquely identifying fluid-phase products by endowing them with fingerprints composed of dispersed colloidal particles, and by reading out those fingerprints on demand using Total Holographic Characterization. A library of chemically inert colloidal particles is developed that can be dispersed into soft materials, the stoichiometry of the mixture encoding user-specified information, including information about the host material. Encoded information then can be recovered by high-speed analysis of holographic microscopy images of the dispersed particles. Specifically, holograms of individual colloidal spheres are analyzed with predictions of the theory of light scattering to measure each sphere's radius and refractive index, thereby building up the distribution of particle properties one particle at a time. A complete analysis of a colloidal fingerprint requires several thousand single-particle holograms and can be completed in ten minutes.
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公开(公告)号:US11977015B2
公开(公告)日:2024-05-07
申请号:US17396980
申请日:2021-08-09
申请人: NEW YORK UNIVERSITY
发明人: David G. Grier , David B. Ruffner , Aaron Yevick , Mark Hannel
IPC分类号: G01N15/02 , G01N15/0227 , G03H1/00 , G03H1/04 , G06V10/143 , G06V20/69 , G06V20/80 , B01L3/00 , G01N15/00 , G01N21/47
CPC分类号: G01N15/0227 , G03H1/0005 , G03H1/0443 , G06V10/143 , G06V20/69 , G06V20/80 , B01L3/5027 , G01N2015/0053 , G01N2015/0233 , G01N2015/03 , G01N2021/4707 , G03H2001/0033 , G03H2001/005 , G03H2001/0447
摘要: Systems and methods for uniquely identifying fluid-phase products by endowing them with fingerprints composed of dispersed colloidal particles, and by reading out those fingerprints on demand using Total Holographic Characterization. A library of chemically inert colloidal particles is developed that can be dispersed into soft materials, the stoichiometry of the mixture encoding user-specified information, including information about the host material. Encoded information then can be recovered by high-speed analysis of holographic microscopy images of the dispersed particles. Specifically, holograms of individual colloidal spheres are analyzed with predictions of the theory of light scattering to measure each sphere's radius and refractive index, thereby building up the distribution of particle properties one particle at a time. A complete analysis of a colloidal fingerprint requires several thousand single-particle holograms and can be completed in ten minutes.
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公开(公告)号:US11747258B2
公开(公告)日:2023-09-05
申请号:US17826848
申请日:2022-05-27
申请人: NEW YORK UNIVERSITY
发明人: David G. Grier , Michael D. Ward , Xiao Zhong , Chen Wang , Laura A. Philips , David B. Ruffner , Fook Chiong Cheong
CPC分类号: G01N15/0227 , G01N15/0211 , G01N15/147 , G01N2015/0038 , G01N2015/0053 , G01N2015/0222 , G01N2015/0233 , G01N2015/1454
摘要: Systems and methods for holographic characterization of protein aggregates. Size and refractive index of individual aggregates in a solution can be determined. Information regarding morphology and porosity can be extracted from holographic data.
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公开(公告)号:US11385157B2
公开(公告)日:2022-07-12
申请号:US16076265
申请日:2017-02-07
申请人: NEW YORK UNIVERSITY
发明人: David G. Grier , Michael D. Ward , Xiao Zhong , Chen Wang , Laura A. Philips , David B. Ruffner , Fook Chiong Cheong
摘要: Systems and methods for holographic characterization of protein aggregates. Size and refractive index of individual aggregates in a solution can be determined. Information regarding morphology and porosity can be extracted from holographic data.
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公开(公告)号:US20130194646A1
公开(公告)日:2013-08-01
申请号:US13753298
申请日:2013-01-29
申请人: New York University
发明人: David B. Ruffner , David G. Grier
IPC分类号: G03H1/04
CPC分类号: G03H1/04 , G03H1/2294 , G03H2001/0077
摘要: Optical conveyors providing motive force to objects. The optical conveyors are one-sided and are able to exert forces on illuminated objects that are directed opposite to the direction of the light's propagation.
摘要翻译: 向物体提供动力的光学输送机。 光学输送机是单面的,并且能够对与光的传播方向相反的照明物体施加力。
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