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公开(公告)号：US20170119889A1
公开(公告)日：2017-05-04
申请号：US15354547
申请日：2016-11-17
发明人： Lei Yu , Gang Zhao , Sang Van , Sanjib Kumar Das , Zhongling Feng , Xiaoli Fu , Xinghe Wang
IPC分类号： A61K47/42 , A61K31/4745 , A61K49/14 , A61K31/704 , A61K49/00 , A61K31/337
CPC分类号： A61K47/42 , A61K31/337 , A61K31/4745 , A61K31/704 , A61K47/56 , A61K47/62 , A61K47/64 , A61K47/645 , A61K49/0041 , A61K49/0056 , A61K49/146 , C08G69/10 , C08G69/48
摘要： Various biodegradable polyglutamate-amino acids comprising recurring units of the general formulae (I) and (II) are prepared. Such polymers are useful for variety of drug, biomolecule and imaging agent delivery applications.
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公开(公告)号：US20140212474A1
公开(公告)日：2014-07-31
申请号：US14167223
申请日：2014-01-29
发明人： Yoshiro Niitsu , Lei Yu , Gang Zhao , Sang Van , Fu Chen
CPC分类号： A61K47/34 , A61K9/127 , A61K31/00 , A61K31/337 , A61K31/7088 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/36 , A61K47/64
摘要： Compositions that can include a carrier, targeting agent, and therapeutic agent are disclosed herein. The therapeutic agent may have a therapeutic activity such as inhibiting fibrosis within a target organ or tissue or inhibiting the growth of a cancer cell.
摘要翻译： 可以包括载体，靶向剂和治疗剂的组合物在本文中公开。 治疗剂可以具有治疗活性，例如抑制靶器官或组织内的纤维化或抑制癌细胞的生长。
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公开(公告)号：US09855338B2
公开(公告)日：2018-01-02
申请号：US15354547
申请日：2016-11-17
发明人： Lei Yu , Gang Zhao , Sang Van , Sanjib Kumar Das , Zhongling Feng , Xiaoli Fu , Xinghe Wang , Yi Jin , Fu Chen
IPC分类号： A61K31/00 , A61K47/42 , A61K49/00 , A61K31/337 , A61K49/14 , A61K31/704 , A61K31/4745 , A61K47/62 , A61K47/64 , A61K47/56
CPC分类号： A61K47/42 , A61K31/337 , A61K31/4745 , A61K31/704 , A61K47/56 , A61K47/62 , A61K47/64 , A61K47/645 , A61K49/0041 , A61K49/0056 , A61K49/146 , C08G69/10 , C08G69/48
摘要： Various biodegradable polyglutamate-amino acids comprising recurring units of the general formulae (I) and (II) are prepared. Such polymers are useful for variety of drug, biomolecule and imaging agent delivery applications.
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