DEVICE FOR MASS SPECTROMETRY, AND MASS SPECTROMETRY APPARATUS AND METHOD
    1.
    发明申请
    DEVICE FOR MASS SPECTROMETRY, AND MASS SPECTROMETRY APPARATUS AND METHOD 有权
    大容量光谱装置和质谱仪器和方法

    公开(公告)号:US20100065735A1

    公开(公告)日:2010-03-18

    申请号:US12561040

    申请日:2009-09-16

    IPC分类号: H01J49/40 H01J49/26

    CPC分类号: H01J49/0418

    摘要: In a device for mass spectrometry, an analyte contained in a sample is desorbed from a surface of the device by irradiating the sample in contact with the surface with measurement light. The device includes a micro-structure having a plurality of metal bodies on a surface of a substrate, and the plurality of metal bodies have sizes that can excite localized plasmons by irradiation with the measurement light. Further, the device includes an initiator fixed at least to a part of a surface of the micro-structure.

    摘要翻译: 在用于质谱的装置中,通过用测量光照射与表面接触的样品,将样品中包含的分析物从装置的表面解吸。 该装置包括在基板的表面上具有多个金属体的微结构,并且多个金属体具有可以通过用测量光照射激发局部等离子体激元的尺寸。 此外,该装置包括至少固定在微结构的表面的一部分上的引发剂。

    Device for mass spectrometry, and mass spectrometry apparatus and method
    2.
    发明授权
    Device for mass spectrometry, and mass spectrometry apparatus and method 有权
    质谱装置,质谱装置及方法

    公开(公告)号:US08278626B2

    公开(公告)日:2012-10-02

    申请号:US12561040

    申请日:2009-09-16

    IPC分类号: H01J27/24 H01J49/16

    CPC分类号: H01J49/0418

    摘要: In a device for mass spectrometry, an analyte contained in a sample is desorbed from a surface of the device by irradiating the sample in contact with the surface with measurement light. The device includes a micro-structure having a plurality of metal bodies on a surface of a substrate, and the plurality of metal bodies have sizes that can excite localized plasmons by irradiation with the measurement light. Further, the device includes an initiator fixed at least to a part of a surface of the micro-structure.

    摘要翻译: 在用于质谱的装置中,通过用测量光照射与表面接触的样品,将样品中包含的分析物从装置的表面解吸。 该装置包括在基板的表面上具有多个金属体的微结构,并且多个金属体具有可以通过用测量光照射激发局部等离子体激元的尺寸。 此外,该装置包括至少固定在微结构的表面的一部分上的引发剂。

    Substrate for mass spectrometry and mass spectrometry method
    3.
    发明授权
    Substrate for mass spectrometry and mass spectrometry method 有权
    基质用于质谱和质谱法

    公开(公告)号:US08008620B2

    公开(公告)日:2011-08-30

    申请号:US12568197

    申请日:2009-09-28

    IPC分类号: H01J49/26

    CPC分类号: H01J49/0418

    摘要: A substrate for mass spectrometry includes a first reflective member that is semi-transmissive/semi-reflective, a transparent member, and a second reflective member that is reflective, sequentially provided to form an optical resonator. The optical resonator includes, on a surface of the first reflective member, a sample separation portion at which surface interaction occurs with a plurality of analytes contained in a sample liquid. The analytes are separated on the sample separation portion to perform mass spectrometry on each of the analytes. A sample in contact with the surface of the first reflective member is irradiated with laser beam L to generate resonance in the optical resonator, and an electric field on the surface of the first reflective member is enhanced by the resonance. The enhanced electric field is utilized to ionize analytes S in the sample and to desorb the analytes S from the surface.

    摘要翻译: 用于质谱的衬底包括半透射/半反射的第一反射构件,透明构件和顺序地设置以形成光谐振器的反射的第二反射构件。 光学谐振器在第一反射构件的表面上包括样品分离部分,在样品分离部分处与样品液体中包含的多种分析物发生表面相互作用。 分析物在样品分离部分上分离,以对每种分析物进行质谱分析。 用激光束L照射与第一反射构件的表面接触的样品,以在光谐振器中产生谐振,并且通过谐振增强第一反射构件表面上的电场。 增强的电场用于电离样品中的分析物S并从表面解吸分析物S.

    SUBSTRATE FOR MASS SPECTROMETRY AND MASS SPECTROMETRY METHOD
    4.
    发明申请
    SUBSTRATE FOR MASS SPECTROMETRY AND MASS SPECTROMETRY METHOD 有权
    基质用于质谱和质谱法

    公开(公告)号:US20100078552A1

    公开(公告)日:2010-04-01

    申请号:US12568197

    申请日:2009-09-28

    IPC分类号: H01J49/26

    CPC分类号: H01J49/0418

    摘要: A substrate for mass spectrometry includes a first reflective member that is semi-transmissive/semi-reflective, a transparent member, and a second reflective member that is reflective, sequentially provided to form an optical resonator. The optical resonator includes, on a surface of the first reflective member, a sample separation portion at which surface interaction occurs with a plurality of analytes contained in a sample liquid. The analytes are separated on the sample separation portion to perform mass spectrometry on each of the analytes. A sample in contact with the surface of the first reflective member is irradiated with laser beam L to generate resonance in the optical resonator, and an electric field on the surface of the first reflective member is enhanced by the resonance. The enhanced electric field is utilized to ionize analytes S in the sample and to desorb the analytes S from the surface.

    摘要翻译: 用于质谱的衬底包括半透射/半反射的第一反射构件,透明构件和顺序地设置以形成光谐振器的反射的第二反射构件。 光学谐振器在第一反射构件的表面上包括样品分离部分,在样品分离部分处与样品液体中包含的多种分析物发生表面相互作用。 分析物在样品分离部分上分离,以对每种分析物进行质谱分析。 用激光束L照射与第一反射构件的表面接触的样品,以在光谐振器中产生谐振,并且通过谐振增强第一反射构件表面上的电场。 增强的电场用于电离样品中的分析物S并从表面解吸分析物S.

    In-vehicle terminal for emergency notification
    5.
    发明授权
    In-vehicle terminal for emergency notification 有权
    车载终端紧急通知

    公开(公告)号:US08391831B2

    公开(公告)日:2013-03-05

    申请号:US13096499

    申请日:2011-04-28

    摘要: An emergency notification in-vehicle terminal mountable to a vehicle is disclosed. The in-vehicle terminal is configured to transmit emergency information to a center in response to detection of an occurrence of an emergency situation involving the vehicle. The in-vehicle terminal determines, in response to the detection of the occurrence of the emergency situation, whether the emergency notification in-vehicle terminal is operating by an electric power of a back-up battery. If it is determined that the emergency notification in-vehicle terminal is operating by the electric power of the back-up battery, the in-vehicle terminal transmits a minimum necessary amount of the emergency information to the center.

    摘要翻译: 公开了可安装于车辆的紧急通知车载终端。 响应于检测到涉及车辆的紧急情况的发生,车载终端被配置为向中心发送紧急信息。 车载终端响应于检测到紧急情况的发生,确定车载终端中的紧急通知是否由备用电池的电力进行操作。 如果确定车载终端中的紧急通知由备用电池的电力进行操作,则车载终端向中心发送最小必需量的紧急信息。

    METHOD AND APPARATUS FOR MEASURING RAMAN SIGNALS
    6.
    发明申请
    METHOD AND APPARATUS FOR MEASURING RAMAN SIGNALS 有权
    用于测量拉曼信号的方法和装置

    公开(公告)号:US20090248367A1

    公开(公告)日:2009-10-01

    申请号:US12409056

    申请日:2009-03-23

    IPC分类号: G06F15/00 G01J3/44

    摘要: A method of measuring Raman signals comprises: an analyte placing step of placing an analyte on a detection surface of a microstructure plate which generates an enhanced electric field when irradiated with excitation light; an irradiating step of irradiating the detection surface with the excitation light so that the enhanced electric field is generated around the detection surface and light is emitted from the analyte and the detection surface to be enhanced by the generated enhanced electric field; a Raman signal obtaining step of detecting the enhanced light to obtain a Raman signal emitted from the analyte and a background signal for use as a reference, the Raman signal and the background signal having respective intensities; and a normalizing step of normalizing the Raman signal from the analyte by dividing the intensity of the Raman signal from the analyte by the intensity of the background signal obtained as the reference.

    摘要翻译: 测量拉曼信号的方法包括:分析物放置步骤,将分析物放置在微细板的检测表面上,当用激发光照射时产生增强的电场; 照射步骤,用激发光照射检测面,使得在检测面周围产生增强的电场,并且从分析物和检测面发射光,通过产生的增强电场来增强; 拉曼信号获取步骤,检测增强光以获得从分析物发射的拉曼信号和用作参考的背景信号,拉曼信号和背景信号具有各自的强度; 以及归一化步骤,通过将来自分析物的拉曼信号的强度除以作为参考获得的背景信号的强度,将来自分析物的拉曼信号归一化。

    Mass spectrometry apparatus and method using the apparatus
    9.
    发明授权
    Mass spectrometry apparatus and method using the apparatus 有权
    质谱装置及使用该装置的方法

    公开(公告)号:US08319178B2

    公开(公告)日:2012-11-27

    申请号:US12785119

    申请日:2010-05-21

    申请人: Naoki Murakami

    发明人: Naoki Murakami

    IPC分类号: H01J49/16 H01J49/40

    摘要: A mass-spectrometry apparatus includes a substrate for mass spectrometry used in surface-assisted laser desorption/ionization mass spectrometry, a light irradiation means that irradiates sample S in contact with a surface of the substrate with measurement light L1 to desorb analyte R in sample S from the surface, a metal probe that generates near-field light at the leading end thereof by irradiation with measurement light L1, a detector that detects desorbed analyte Ri, and an analysis means that performs mass spectrometry on analyte R based on a detection result by the detector. The leading end of the metal probe is arranged in such a manner that the near-field light generated by irradiation with measurement light L1 is in contact with a measurement light irradiation portion of sample S. The metal probe is arranged, with respect to the measurement light irradiation portion, at a position different from the direction of the detector.

    摘要翻译: 质谱装置包括用于表面辅助激光解吸/电离质谱法中的质谱用基板,光照射装置,用测量光L1照射与基板表面接触的样品S,以解吸样品S中的分析物R 从表面开始,通过照射测量光L1在其前端产生近场光的金属探针,检测解吸附的分析物Ri的检测器和基于检测结果对分析物R进行质谱分析的分析装置 检测器。 金属探针的前端以如下方式配置,使得通过照射测量光L1产生的近场光与样品S的测量光照射部分接触。金属探针相对于测量 在与检测器的方向不同的位置处的光照射部分。

    Method and apparatus for measuring raman signals
    10.
    发明授权
    Method and apparatus for measuring raman signals 有权
    用于测量拉曼信号的方法和装置

    公开(公告)号:US08213004B2

    公开(公告)日:2012-07-03

    申请号:US12409056

    申请日:2009-03-23

    IPC分类号: G01J3/44

    摘要: A method of measuring Raman signals comprises: an analyte placing step of placing an analyte on a detection surface of a microstructure plate which generates an enhanced electric field when irradiated with excitation light; an irradiating step of irradiating the detection surface with the excitation light so that the enhanced electric field is generated around the detection surface and light is emitted from the analyte and the detection surface to be enhanced by the generated enhanced electric field; a Raman signal obtaining step of detecting the enhanced light to obtain a Raman signal emitted from the analyte and a background signal for use as a reference, the Raman signal and the background signal having respective intensities; and a normalizing step of normalizing the Raman signal from the analyte by dividing the intensity of the Raman signal from the analyte by the intensity of the background signal obtained as the reference.

    摘要翻译: 测量拉曼信号的方法包括:分析物放置步骤,将分析物放置在微细板的检测表面上,当用激发光照射时产生增强的电场; 照射步骤,用激发光照射检测面,使得在检测面周围产生增强的电场,并且从分析物和检测面发射光,通过产生的增强电场来增强; 拉曼信号获取步骤,检测增强光以获得从分析物发射的拉曼信号和用作参考的背景信号,拉曼信号和背景信号具有各自的强度; 以及归一化步骤,通过将来自分析物的拉曼信号的强度除以作为参考获得的背景信号的强度,将来自分析物的拉曼信号归一化。