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1.
公开(公告)号:US20140377360A1
公开(公告)日:2014-12-25
申请号:US14358588
申请日:2012-11-09
CPC分类号: A61K38/185 , A61K9/1641 , A61K9/1647 , A61K9/167 , A61K9/5031 , A61K9/5036 , A61K38/1709 , A61K38/18 , A61K38/1825 , A61K38/1858 , A61K38/1866 , A61K38/2066 , A61K38/30
摘要: A composition for controlled release of a physiologically active substance can release a physiologically active substance in vivo at the desired timing. The composition includes an inner layer that is formed of a biodegradable substance that supports a physiologically active substance, and an outer layer that is formed of a biodegradable substance that differs from that of the inner layer.
摘要翻译: 用于控制释放生理活性物质的组合物可以在期望的时间在体内释放生理活性物质。 该组合物包括由支持生理活性物质的生物降解性物质形成的内层和由与内层不同的生物降解性物质形成的外层。
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2.
公开(公告)号:US09446098B2
公开(公告)日:2016-09-20
申请号:US14358588
申请日:2012-11-09
CPC分类号: A61K38/185 , A61K9/1641 , A61K9/1647 , A61K9/167 , A61K9/5031 , A61K9/5036 , A61K38/1709 , A61K38/18 , A61K38/1825 , A61K38/1858 , A61K38/1866 , A61K38/2066 , A61K38/30
摘要: A composition for controlled release of a physiologically active substance can release a physiologically active substance in vivo at the desired timing. The composition includes an inner layer that is formed of a biodegradable substance that supports a physiologically active substance, and an outer layer that is formed of a biodegradable substance that differs from that of the inner layer.
摘要翻译: 用于控制释放生理活性物质的组合物可以在期望的时间在体内释放生理活性物质。 该组合物包括由支持生理活性物质的生物降解性物质形成的内层和由与内层不同的生物降解性物质形成的外层。
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公开(公告)号:US11655273B2
公开(公告)日:2023-05-23
申请号:US16629494
申请日:2018-07-09
发明人: Hiromi Kitano , Tadashi Nakaji , Yuki Usui , Taito Nishino , Takahiro Kishioka
IPC分类号: C12N5/07 , C08G61/04 , C07K7/62 , C08F220/36 , B01J20/32 , C08F220/40 , C09D133/10 , C09D133/14 , C12M1/00 , C12N5/0775
CPC分类号: C07K7/62 , B01J20/3204 , B01J20/327 , B01J20/3274 , B01J20/3285 , C08F220/365 , C08F220/40 , C09D133/10 , C09D133/14 , C12M23/20 , C12N5/0663 , C12N2533/30 , C08F220/40 , C08F220/387 , C08F230/085 , C08F220/40 , C08F220/387
摘要: Provided are a ligand-bearing substrate which has a surface at least partially coated with a polymer (P3) containing structural units represented by the formulae (1a) and (1b) (in the formulae, R1, R2, X, Y, L, Q1, Q2, Q3, m1, m2 and n are as described in the claims and description); a raw material for such a substrate; and a method for producing such substrates.
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