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    User interface for finding similar documents
    1.
    发明授权
    User interface for finding similar documents 有权
    用于查找类似文档的用户界面

    公开(公告)号：US09075498B1

    公开(公告)日：2015-07-07

    申请号：US13335809

    申请日：2011-12-22

    申请人： Nelson Murray Wiggins ,  Karen Williams ,  Gary Steven Lehrman ,  Kurt Leafstrand

    发明人： Nelson Murray Wiggins ,  Karen Williams ,  Gary Steven Lehrman ,  Kurt Leafstrand

    IPC分类号： G06F3/0481 ,  G06F17/30

    CPC分类号： G06F3/0481 ,  G06F3/04847 ,  G06F17/30554 ,  G06F17/30687

    摘要： A computing device determines counts of documents that are similar to a reference document for a set of similarity ratings. Each similarity rating is based on a number of co-occurring terms between the reference document and corresponding similar documents. The computing device present the reference document and a GUI element pertaining to the documents similar to the reference document in a graphical user interface (GUI). Upon a selection of the GUI element, the computing device presents a visual representation of a correlation between the counts of similar documents and the similarity ratings in the GUI. The visual representation is provided prior to displaying at least one of the similar documents.

    摘要翻译： 计算设备确定与一组相似性等级的参考文档类似的文档的计数。 每个相似性评级是基于参考文档和相应的类似文档之间的多个共同出现的术语。 计算设备在图形用户界面（GUI）中呈现参考文档和类似于参考文档的文档的GUI元素。 在GUI元素的选择之后，计算设备呈现类似文档的计数与GUI中的相似性等级之间的相关性的视觉表示。 在显示至少一个相似文档之前提供视觉表示。

    Indolizine Derivatives
    3.
    发明申请
    Indolizine Derivatives 审中-公开
    中氮衍生物

    公开(公告)号：US20090163534A1

    公开(公告)日：2009-06-25

    申请号：US11993412

    申请日：2006-06-26

    申请人： George Hynd ,  Nicholas Charles Ray ,  Harry Finch ,  David Middlemiss ,  Michael Colin Cramp ,  Paul Matthew Blaney ,  Karen Williams ,  Yan Griffon ,  Trevor Keith Harrison ,  Peter Crackett

    发明人： George Hynd ,  Nicholas Charles Ray ,  Harry Finch ,  David Middlemiss ,  Michael Colin Cramp ,  Paul Matthew Blaney ,  Karen Williams ,  Yan Griffon ,  Trevor Keith Harrison ,  Peter Crackett

    IPC分类号： A61K31/437 ,  C07D221/04 ,  A61P29/00

    CPC分类号： C07D471/04

    摘要： Compounds of formula (I) are ligands of the CRTH2 receptor and are useful in the treatment of respiratory disease: Formula (I) wherein R1, R2, R3 and R4 each independently are hydrogen, C1C6alkyl, fully or partially fluorinated C1C6alkyl, halo, —S(O)nR10, —SO2N(R10)2, —N(R10)2, —C(O)N(R10)2, —NR10C(O)R9, —CO2R10, —C(O)R9, —NO2, —CN or —OR11; wherein each R9 is independently C1C6alkyl, aryl, heteroaryl; R10 is independently hydrogen, C1C6alkyl, aryl, or heteroaryl; R11 is hydrogen, C1C6alkyl, fully or partially fluorinated C1C6alkyl or a group —SO2R9; n is 0, 1 or 2; R5 is C1C6alkyl, fully or partially fluorinated C1C6alkyl. C1C6alkenyl, C1C6alkynyl, optionally substituted aryl, or optionally substituted heteroaryl; R6 is hydrogen, C1C6alkyl or fully or partially fluorinated C1C6alkyl; R7 and R5 are independently hydrogen or C1C6alkyl, or R7 and R5 together with the atom to which they are attached form a cycloalkyl group; and X is —CHR6—, —S(O)n—, —NR6SO2— or —SO2NR6— wherein n is 0, 1 or 2.

    摘要翻译： 式（I）化合物是CRTH2受体的配体，可用于治疗呼吸系统疾病：其中R 1，R 2，R 3和R 4各自独立地为氢，C 1 -C 6烷基，完全或部分氟化的C 1 -C 6烷基，卤素， S（O）nR10，-SO2N（R10）2，-N（R10）2，-C（O）N（R10）2，-NR10C（O）R9，-CO2R10，-C（O） ，-CN或-OR11; 其中每个R 9独立地为C 1 -C 6烷基，芳基，杂芳基; R 10独立地是氢，C 1 -C 6烷基，芳基或杂芳基; R 11是氢，C 1 -C 6烷基，完全或部分氟化的C 1 -C 6烷基或基团-SO 2 R 9; n为0,1或2; R5是C1C6烷基，完全或部分氟化的C1C6烷基。 C 1 -C 6烯基，C 1 -C 6炔基，任选取代的芳基或任选取代的杂芳基; R6是氢，C1C6烷基或完全或部分氟化的C 1 -C 6烷基; R 7和R 5独立地为氢或C 1 -C 6烷基，或者R 7和R 5与它们所连接的原子一起形成环烷基; 且X为-CHR 6 - ， - S（O）n - ， - NR 6 SO 2 - 或-SO 2 NR 6 - ，其中n为0,1或2。

    Method and apparatus for previewing a panoramic image on a digital camera
    4.
    发明申请
    Method and apparatus for previewing a panoramic image on a digital camera 审中-公开
    用于在数码相机上预览全景图像的方法和装置

    公开(公告)号：US20060182437A1

    公开(公告)日：2006-08-17

    申请号：US11055885

    申请日：2005-02-11

    申请人： Karen Williams ,  Christopher Webb ,  Angelica Quintana

    发明人： Karen Williams ,  Christopher Webb ,  Angelica Quintana

    IPC分类号： H04N5/225

    CPC分类号： H04N5/2624 ,  H04N5/23238

    摘要： A camera and related methodology in which a stitched panoramic image may be generated from a series of individual image frames onboard the camera and displayed on the camera display in a “real-time” environment. This allows the user to preview the completed panorama on the camera without the need to first upload the image frames onto a support computer. In this manner, the user is able to identify potential problems with the panorama and, if necessary, reacquire the individual image frames. In order to reduce the amount of onboard processor power and/or memory required, stitching may be performed on relatively lower resolution image frame files within the camera. When the preview indicates that image data for the panorama has been successfully acquired, then the full resolution image data may be uploaded to a support computer for processing.

    摘要翻译： 相机和相关方法，其中可以从相机上的一系列单独的图像帧生成拼接的全景图像并且在“实时”环境中显示在相机显示器上。 这允许用户在相机上预览完成的全景图，而不需要首先将图像帧上传到支持计算机上。 以这种方式，用户能够识别全景的潜在问题，并且如果需要，重新获取各个图像帧。 为了减少板载处理器的功率和/或所需的存储器的数量，可以在相机内相对较低分辨率的图像帧文件上执行缝合。 当预览指示已经成功获取了全景图像数据时，则可以将全分辨率图像数据上传到支持计算机进行处理。

    N-SUBSTITUTED AZAINDOLES AND METHODS OF USE
    7.
    发明申请
    N-SUBSTITUTED AZAINDOLES AND METHODS OF USE 有权
    N-取代的胺和其使用方法

    公开(公告)号：US20100216768A1

    公开(公告)日：2010-08-26

    申请号：US12664303

    申请日：2008-06-11

    申请人： Hazel Joan Dyke ,  Stephen Price ,  Karen Williams

    发明人： Hazel Joan Dyke ,  Stephen Price ,  Karen Williams

    IPC分类号： A61K31/50 ,  C07D471/04 ,  A61K31/437 ,  C07D487/04 ,  A61P29/00

    CPC分类号： C07D471/04

    摘要： The invention relates to N-substituted azaindolyl compounds of Formula I with anti-cancer and/or anti-inflammatory activity and more specifically to N-substituted azaindolyl compounds which inhibit MEK kinase activity. The invention provides compositions and methods useful for inhibiting abnormal cell growth or treating a hyperproliferative disorder, or treating an inflammatory disease in a mammal. The invention also relates to methods of using the compounds for in vitro, in situ, and in vivo diagnosis or treatment of mammalian cells, or associated pathological conditions.

    摘要翻译： 本发明涉及具有抗癌和/或抗炎活性的更优选的具有抗癌和/或抗炎活性的式I的N-取代的氮杂吲哚基化合物，更具体地涉及抑制MEK激酶活性的N-取代的阿魏酰基化合物。 本发明提供了可用于抑制异常细胞生长或治疗过度增殖性疾病或治疗哺乳动物炎性疾病的组合物和方法。 本发明还涉及将化合物用于体外，原位和体内诊断或治疗哺乳动物细胞或相关病理状况的方法。

    AZA-benzothiophenyl compounds and methods of use
    10.
    发明申请
    AZA-benzothiophenyl compounds and methods of use 有权
    AZA-苯并噻吩基化合物及其使用方法

    公开(公告)号：US20080081821A1

    公开(公告)日：2008-04-03

    申请号：US11894345

    申请日：2007-08-20

    申请人： Pascal Savy ,  Stephen Price ,  Hazel Dyke ,  John Montana ,  Karen Williams ,  Mark Stanley ,  Liang Bao

    发明人： Pascal Savy ,  Stephen Price ,  Hazel Dyke ,  John Montana ,  Karen Williams ,  Mark Stanley ,  Liang Bao

    IPC分类号： A61K31/44 ,  A61P43/00 ,  C07D471/02

    CPC分类号： C07D495/04

    摘要： The invention relates to azabenzothiophenyl compounds of Formula I with anti-cancer and/or anti-inflammatory activity and more specifically to azabenzothiophenyl compounds which inhibit MEK kinase activity. The invention provides compositions and methods useful for inhibiting abnormal cell growth or treating a hyperproliferative disorder, or treating an inflammatory disease in a mammal. The invention also relates to methods of using the compounds for in vitro, in situ, and in vivo diagnosis or treatment of mammalian cells, or associated pathological conditions.

    摘要翻译： 本发明涉及具有抗癌和/或抗炎活性的式I的氮杂苯并噻吩基化合物，更具体地涉及抑制MEK激酶活性的氮杂苯并噻吩基化合物。 本发明提供了可用于抑制异常细胞生长或治疗过度增殖性疾病或治疗哺乳动物炎性疾病的组合物和方法。 本发明还涉及将化合物用于体外，原位和体内诊断或治疗哺乳动物细胞或相关病理状况的方法。