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公开(公告)号：US20230241375A1
公开(公告)日：2023-08-03
申请号：US18173893
申请日：2023-02-24
申请人： NEURAXIS, INC.
CPC分类号： A61N1/0529 , A61N1/0551 , A61N1/36071 , A61K31/485
摘要： An auricular nerve field stimulation device may include a first plurality of electrodes arranged to contact a ventral aspect of an auricle, a second plurality of electrodes arranged to contact a dorsal aspect of the auricle, and electrical circuitry coupled to the electrodes and configured to selectively apply electrical stimulation signals to the electrodes to cause a first set of trans-auricular currents to flow through the auricle between the first plurality of electrodes and respective ones of the second plurality of electrodes paired therewith according to a first pairing, and to cause a second set of trans-auricular currents to flow through the auricle between the first plurality of electrodes and respective ones of the second plurality of electrodes paired therewith according to a second pairing different from the first pairing, the first and second sets of trans-auricular currents to stimulate at least one auricular nerve field within the auricle. Methods of utilizing nerve field stimulation device.
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公开(公告)号：US11654082B2
公开(公告)日：2023-05-23
申请号：US17363620
申请日：2021-06-30
申请人： Neuraxis, Inc.
CPC分类号： A61H39/002 , A61H39/02 , A61N1/0551 , A61N1/36135 , A61H2201/5005 , A61H2201/5007 , A61H2201/5023 , A61H2201/5033 , A61H2201/5038 , A61H2201/5058 , A61H2205/027 , A61H2230/105 , A61H2230/405 , A61H2230/505 , A61H2230/605
摘要： An auricular peripheral nerve field stimulator includes at least one therapy electrode configured for percutaneous insertion into an auricle of a human ear near at least one neurovascular bundle, and an electrical stimulation device electrically coupled to the at least one therapy electrode, the electrical stimulation device programmed to generate and deliver electrical stimulation signals, with defined stimulation parameters, to the percutaneously inserted at least one therapy electrode to stimulate at least one auricular peripheral nerve field within the auricle, the defined stimulation parameters including a defined signal amplitude, a defined pulse frequency, a defined pulse width, a defined duty cycle and a defined stimulation signal duration.
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公开(公告)号：US20240033505A1
公开(公告)日：2024-02-01
申请号：US18377968
申请日：2023-10-09
申请人： NEURAXIS, INC.
CPC分类号： A61N1/0529 , A61N1/0551 , A61N1/36071 , A61K31/485
摘要： A method for treating pain or discomfort in a patient is disclosed. The method comprises stimulating a cranial nerve with an electrical signal. The pain or discomfort may be a withdrawal symptom. The cranial nerve may be in an auricular area of the patient. The cranial nerve may be cranial nerve V, cranial nerve VII, cranial nerve IX, cranial nerve X, or branches of greater and lesser occipital nerves thereof and their associated neurovascular bundles. The withdrawal symptom may result from cessation of an opioid. The method may further comprise administering a secondary drug treats one or more of the withdrawal symptoms and addiction. The secondary drug may be administered about one day to about one week after initiating the stimulating step.
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公开(公告)号：US11813448B2
公开(公告)日：2023-11-14
申请号：US17725761
申请日：2022-04-21
申请人： NEURAXIS, INC.
IPC分类号： A61N1/05 , A61N1/36 , A61K31/485
CPC分类号： A61N1/0529 , A61N1/0551 , A61N1/36071 , A61K31/485
摘要： A method for treating pain or discomfort in a patient is disclosed. The method comprises stimulating a cranial nerve with an electrical signal. The pain or discomfort may be a withdrawal symptom. The cranial nerve may be in an auricular area of the patient. The cranial nerve may be cranial nerve V, cranial nerve VII, cranial nerve IX, cranial nerve X, or branches of greater and lesser occipital nerves thereof and their associated neurovascular bundles. The withdrawal symptom may result from cessation of an opioid. The method may further comprise administering a secondary drug treats one or more of the withdrawal symptoms and addiction. The secondary drug may be administered about one day to about one week after initiating the stimulating step.
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公开(公告)号：US20240315923A1
公开(公告)日：2024-09-26
申请号：US18736834
申请日：2024-06-07
申请人： Neuraxis, Inc.
CPC分类号： A61H39/002 , A61H39/02 , A61N1/0551 , A61N1/36135 , A61H2201/5005 , A61H2201/5007 , A61H2201/5023 , A61H2201/5033 , A61H2201/5038 , A61H2201/5058 , A61H2205/027 , A61H2230/105 , A61H2230/405 , A61H2230/505 , A61H2230/605
摘要： An auricular peripheral nerve field stimulator may include at least one therapy electrode configured for percutaneous insertion into an auricle of a human ear near at least one neurovascular bundle located therein, and an electrical stimulation device electrically coupled to the electrical stimulation device, the electrical stimulation device programmed to generate and deliver electrical stimulation signals, with defined stimulation parameters, to the at least one therapy electrode to stimulate, with the at least one therapy electrode percutaneously inserted, at least one auricular peripheral nerve field within the auricle, the defined stimulation parameters including a defined pulse frequency and at least one of a defined pulse width and a defined duty cycle.
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公开(公告)号：US20230190577A1
公开(公告)日：2023-06-22
申请号：US18154375
申请日：2023-01-13
申请人： Neuraxis, Inc.
CPC分类号： A61H39/002 , A61H39/02 , A61N1/0551 , A61N1/36135 , A61H2201/5005 , A61H2201/5007 , A61H2201/5033 , A61H2205/027 , A61H2201/5038 , A61H2201/5058 , A61H2230/105 , A61H2230/405 , A61H2230/505 , A61H2230/605 , A61H2201/5023
摘要： An auricular peripheral nerve field stimulator may include at least one therapy electrode configured for percutaneous insertion into an auricle of a human ear near at least one neurovascular bundle located therein, and an electrical stimulation device electrically coupled to the electrical stimulation device, the electrical stimulation device programmed to generate and deliver electrical stimulation signals, with defined stimulation parameters, to the at least one therapy electrode to stimulate, with the at least one therapy electrode percutaneously inserted, at least one auricular peripheral nerve field within the auricle, the defined stimulation parameters including a defined pulse frequency and at least one of a defined pulse width and a defined duty cycle.
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公开(公告)号：US12097371B2
公开(公告)日：2024-09-24
申请号：US17715121
申请日：2022-04-07
申请人： Neuraxis, Inc.
CPC分类号： A61N1/36038 , A61N1/0456 , A61N1/0541 , A61N1/36017 , A61N1/36021 , A61N1/36036
摘要： An auricular nerve field stimulation device may include first non-percutaneous electrodes arranged to contact a ventral aspect of an auricle, second non-percutaneous electrodes arranged to contact a dorsal aspect of the auricle, and electrical circuitry coupled to the electrodes and configured to selectively apply electrical stimulation signals to the electrodes to cause a first set of trans-auricular currents to flow through the auricle between the first electrodes and respective ones of the second electrodes paired therewith according to a first pairing, and to cause a second set of trans-auricular currents to flow through the auricle between the first electrodes and respective ones of the second electrodes paired therewith according to a second pairing different from the first pairing, the first and second sets of trans-auricular currents to stimulate at least one auricular nerve field within the auricle.
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公开(公告)号：US12029701B2
公开(公告)日：2024-07-09
申请号：US18154375
申请日：2023-01-13
申请人： Neuraxis, Inc.
CPC分类号： A61H39/002 , A61H39/02 , A61N1/0551 , A61N1/36135 , A61H2201/5005 , A61H2201/5007 , A61H2201/5023 , A61H2201/5033 , A61H2201/5038 , A61H2201/5058 , A61H2205/027 , A61H2230/105 , A61H2230/405 , A61H2230/505 , A61H2230/605
摘要： An auricular peripheral nerve field stimulator may include at least one therapy electrode configured for percutaneous insertion into an auricle of a human ear near at least one neurovascular bundle located therein, and an electrical stimulation device electrically coupled to the electrical stimulation device, the electrical stimulation device programmed to generate and deliver electrical stimulation signals, with defined stimulation parameters, to the at least one therapy electrode to stimulate, with the at least one therapy electrode percutaneously inserted, at least one auricular peripheral nerve field within the auricle, the defined stimulation parameters including a defined pulse frequency and at least one of a defined pulse width and a defined duty cycle.
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公开(公告)号：US20220387817A1
公开(公告)日：2022-12-08
申请号：US17830411
申请日：2022-06-02
申请人： Neuraxis, Inc.
发明人： Christopher R. Brown , Mark T. Volz
IPC分类号： A61N5/06
摘要： A device for eradicating at least one pathogen in a nasal passage of a human or animal may include a housing configured to be inserted into the nasal passage, at least one radiation source, configured to emit radiation, coupled to the housing such that at least a portion of a radiation emitting surface, upon insertion of the housing into the nasal passage, faces at least a portion of nasal lining of the nasal passage, and an electrical circuit carried by the housing and electrically connected to the at least one radiation source, the electrical circuit including at least one circuit component for controlling the at least one radiation source to emit the radiation to irradiate the nasal passage, the emitted radiation having a frequency or range of frequencies at which the at least one pathogen in the nasal passage, when irradiated by the emitted radiation, is eradicated.
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