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公开(公告)号：US09304100B2
公开(公告)日：2016-04-05
申请号：US13744533
申请日：2013-01-18
申请人： Niclas Roxhed , Goran Stemme , Hithesh K. Gatty
发明人： Niclas Roxhed , Goran Stemme , Hithesh K. Gatty
IPC分类号： G01N27/404 , G01N33/497
CPC分类号： G01N27/4045 , G01N33/497
摘要： A miniaturised electrochemical sensor for detection of a component in a gas is provided. The sensor comprises a reference electrode, a counter electrode and a structure comprising a plurality of passages delineated by walls extending along the passages. A working electrode covers the walls of the structure and a layer of an ionomer covers at least part of the working electrode along the walls of the structure. The layer of ionomer is in ion conducting contact with the electrodes. The disclosure further relates to a method of fabricating a miniaturised electrochemical sensor and to a device for measuring content of NO in exhaled breath comprising such a miniaturised electrochemical sensor.
摘要翻译： 提供了用于检测气体中的组分的小型化学电化学传感器。 传感器包括参比电极，对电极和包括沿着通道延伸的壁所描绘的多个通道的结构。 工作电极覆盖结构的壁，并且离子交换聚合物层沿着结构的壁覆盖工作电极的至少一部分。 离聚物层与电极离子导电接触。 本发明还涉及一种制造小型化学电化学传感器的方法和用于测量包含这种小型化学电化学传感器的呼出气体中的NO含量的装置。
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公开(公告)号：US20140207014A1
公开(公告)日：2014-07-24
申请号：US14157810
申请日：2014-01-17
CPC分类号： A61B5/087 , A61B5/082 , A61B5/097 , A61B2562/028 , A61B2562/12
摘要： A micromachined fluid flow regulating device is disclosed comprising a fluid flow channel, at least one flow orifice formed in the channel, defining an inlet portion of the channel upstream of the flow orifice, an outlet portion of the channel downstream of the flow orifice, the fluid having a flow direction from the inlet portion to the outlet portion of the channel. At least one piston is arranged upstream of the flow orifice, movably suspended in the channel by a spring means such that the piston is movable by the fluid in the flow direction of the fluid, towards the flow orifice, to regulate a fluid flow through the flow orifice. The disclosure further relates to the use of a micromachined flow regulating device in a breath analysis device and to a method of fabricating a flow regulating device.
摘要翻译： 公开了一种微加工流体流量调节装置，其包括流体流动通道，形成在通道中的至少一个流动孔口，在流动孔口的上游限定通道的入口部分，流动孔下游的通道的出口部分， 流体具有从通道的入口部分到出口部分的流动方向。 至少一个活塞布置在流动孔口的上游，通过弹簧装置可移动地悬挂在通道中，使得活塞可以通过流体沿着流体的流动方向移动到流动孔口，以调节通过流体的流体流动 流量孔。 本发明还涉及在呼吸分析装置中使用微加工流量调节装置以及制造流量调节装置的方法。
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公开(公告)号：US10525239B2
公开(公告)日：2020-01-07
申请号：US14673993
申请日：2015-03-31
申请人： Niclas Roxhed , Staffan Johansson , Göran Stemme , Anders Eklund , Jan Malm
发明人： Niclas Roxhed , Staffan Johansson , Göran Stemme , Anders Eklund , Jan Malm
摘要： The disclosure relates to a cerebrospinal fluid (CSF) shunt for treatment of hydrocephalus, comprising a valve having an inlet port and an outlet port, which ports are for draining CSF, and a control port for regulating the drainage of CSF through the valve according to a hydrostatic pressure provided to the control port, which hydrostatic pressure is dependent on the body position of the patient. The disclosure further relates to a method for treatment of hydrocephalus comprising regulating drainage of CSF based on a hydrostatic pressure that is dependent on the body position of the patient.
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公开(公告)号：US11504959B2
公开(公告)日：2022-11-22
申请号：US17425749
申请日：2020-01-24
发明人： Arne Quellmalz , Xiaojing Wang , Kristinn Gylfason , Niclas Roxhed , Göran Stemme , Frank Niklaus
摘要： A method for transferring an atomically thin layer comprising providing a target substrate and a donor substrate on which a first atomically thin layer has been formed. The method further comprises disposing an adhesion layer at the donor substrate or at the target substrate. The method further comprises bringing the target substrate and the donor substrate together. Further, the method comprises bonding together the donor substrate, the adhesion layer and the target substrate and removing the donor substrate.
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公开(公告)号：US20240023850A1
公开(公告)日：2024-01-25
申请号：US18249196
申请日：2021-10-14
申请人： Niclas Roxhed , Mikolaj Dobielewski , Göran Stemme
发明人： Niclas Roxhed , Mikolaj Dobielewski , Göran Stemme
CPC分类号： A61B5/150022 , A61B5/150175 , A61B5/15045 , A61B5/150458 , A61B5/150465 , A61B5/150984 , A61B5/15111 , A61B5/15117 , A61B5/15144
摘要： A microneedle (100) for extracting a blood sample from the skin (10) of a mammal subject is disclosed. The microneedle comprises at least one substantially flat blade (110) comprising at least one cutting edge (120a, 120b) configured to incise the skin of the mammal subject, and at least one microchannel (130) comprising an opening (132) and a passage (134). The at least one microchannel is arranged adjacent to the at least one blade and configured to be inserted into the skin of the mammal subject together with the at least one blade. The passage is configured to transport the blood sample away from the opening via capillary action. A device (200) for extracting a blood sample from a mammal subject comprising a microneedle is also disclosed.
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公开(公告)号：US09687178B2
公开(公告)日：2017-06-27
申请号：US14157810
申请日：2014-01-17
申请人： Niclas Roxhed
CPC分类号： A61B5/087 , A61B5/082 , A61B5/097 , A61B2562/028 , A61B2562/12
摘要： A micromachined fluid flow regulating device is disclosed comprising a fluid flow channel, at least one flow orifice formed in the channel, defining an inlet portion of the channel upstream of the flow orifice, an outlet portion of the channel downstream of the flow orifice, the fluid having a flow direction from the inlet portion to the outlet portion of the channel. At least one piston is arranged upstream of the flow orifice, movably suspended in the channel by a spring means such that the piston is movable by the fluid in the flow direction of the fluid, towards the flow orifice, to regulate a fluid flow through the flow orifice. The disclosure further relates to the use of a micromachined flow regulating device in a breath analysis device and to a method of fabricating a flow regulating device.
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