Polypeptide complex of TRPM8 and calmodulin and its uses thereof
    5.
    发明申请
    Polypeptide complex of TRPM8 and calmodulin and its uses thereof 有权
    TRPM8的多肽复合物和钙调蛋白及其用途

    公开(公告)号:US20070105155A1

    公开(公告)日:2007-05-10

    申请号:US11590503

    申请日:2006-10-31

    IPC分类号: G01N33/53

    摘要: The present invention discovered that a mammalian TRPM8 binds to calmodulin. The present invention provides a polypeptide complex comprising a cold-menthol receptor (TRPM8) or an active fragment or derivative of TRPM8 and a calmodulin or an active fragment or derivative of calmodulin, and the uses of the polypeptide complex.

    摘要翻译: 本发明发现哺乳动物TRPM8与钙调蛋白结合。 本发明提供了包含冷薄荷醇受体(TRPM8)或TRPM8的活性片段或衍生物和钙调蛋白或钙调蛋白的活性片段或衍生物的多肽复合物,以及多肽复合物的用途。

    Method of connecting meshes
    10.
    发明授权
    Method of connecting meshes 有权
    连接网格的方法

    公开(公告)号:US09123166B2

    公开(公告)日:2015-09-01

    申请号:US13358077

    申请日:2012-01-25

    IPC分类号: G06F17/50 G06T17/20

    CPC分类号: G06T17/20

    摘要: A method of connecting three-dimensional structured meshes to form a conformal mesh, for solutions of flow problems, including: forming an interface by overlaying surfaces of two structured meshes; defining an interface set of mesh points in the interface; merging mesh points in the interface set that are within a predetermined distance of each other and projecting mesh points of one mesh in the interface that are within a predetermined distance of a line of the other mesh; generating an interface layer in the form of an unstructured mesh; and inserting a node at the center of each hexahedra, and producing an unstructured layer of cells between the two structured meshes by joining the nodes to the mesh points of the interface layer.

    摘要翻译: 一种连接三维结构网格以形成共形网格的方法,用于解决流动问题,包括:通过覆盖两个结构化网格的表面形成界面; 定义接口中的网格点的接口集; 将界面集合中的网格点合并在彼此的预定距离内,并且在界面中的一个网格的网格点在另一个网格的线的预定距离内预定的距离; 生成非结构化网格形式的界面层; 并在每个六面体的中心插入节点,并通过将节点连接到界面层的网格点,在两个结构化网格之间产生非结构化的单元格层。