公开(公告)号：US06277964B1

公开(公告)日：2001-08-21

申请号：US09265872

申请日：1999-03-11

申请人： Nobuhiko Yamashita ,  Kazunobu Miura ,  Naoya Ichimura ,  Chiwa Kataoka ,  Junko Sakaki ,  Yutaka Ohtani ,  Hirohisa Kitagawa

发明人： Nobuhiko Yamashita ,  Kazunobu Miura ,  Naoya Ichimura ,  Chiwa Kataoka ,  Junko Sakaki ,  Yutaka Ohtani ,  Hirohisa Kitagawa

IPC分类号： C07K1644

CPC分类号： C07K16/44 ,  G01N33/5308 ,  Y10S530/808 ,  Y10S530/809

摘要： The present invention provides monoclonal antibodies suitable for monitoring polycyclic aromatic hydrocarbons (PAHs) by an immunoasay, hybridoma cell lines producing said antibodies, and an immunoassay for analyzing PAHs in a sample using said monoclonal antibodies. In addition, the present invention provides PAH conjugates useful as an immunogen in preparing said antibodies and as a standard substance in a competitive assay.

摘要翻译： 本发明提供了适用于通过免疫测定监测多环芳烃（PAH）的单克隆抗体，产生所述抗体的杂交瘤细胞系以及使用所述单克隆抗体分析样品中PAH的免疫测定法。 此外，本发明提供了在竞争性测定中用作制备所述抗体和作为标准物质的免疫原的PAH缀合物。

公开(公告)号：US06255515B1

公开(公告)日：2001-07-03

申请号：US09341844

申请日：1999-08-31

申请人： Taku Kato ,  Kazuya Okano ,  Toshihiko Sugano ,  Yutaka Ohtani ,  Hirohisa Kitagawa ,  Sugio Nishimura

发明人： Taku Kato ,  Kazuya Okano ,  Toshihiko Sugano ,  Yutaka Ohtani ,  Hirohisa Kitagawa ,  Sugio Nishimura

IPC分类号： C07F708

CPC分类号： C08F297/08 ,  C07F7/0827 ,  C07F7/30 ,  C07F17/00 ,  C08F4/65912 ,  C08F4/65916 ,  C08F10/00 ,  C08F110/06 ,  C08F4/025 ,  C08F4/65927 ,  C08F2500/12 ,  C08F2500/03

摘要： An alkali metal- or alkali earth metal-containing organic compound (i) is reacted with a leaving group- and silicon- or germanium-containing compound (ii) in the presence of a nitrogen-containing aromatic heterocyclic compound. By such a method, it is possible to produce a silicon- or germanium-containing organic compound, for example, a cyclopentadienyl compound cross-linked by a silicon atom or a germanium atom, typically a cyclopentadienyl compound which is substituted with a substituted or unsubstituted silyl or germyl group, for a short time with a high yield.

摘要翻译： 含碱金属或碱土金属的有机化合物（i）在含氮芳族杂环化合物的存在下与离去基团和含硅或锗的化合物（ⅱ）反应。 通过这种方法，可以制备含硅或锗的有机化合物，例如由硅原子或锗原子交联的环戊二烯基化合物，通常为被取代或未取代的环戊二烯基化合物 甲硅烷基或甲硅烷基，短时间内具有高产率。

公开(公告)号：US06960672B2

公开(公告)日：2005-11-01

申请号：US10473252

申请日：2002-03-28

申请人： Masahide Nakayama ,  Keiichi Tsuto ,  Takenori Hirano ,  Tsutomu Sakai ,  Ayato Kawashima ,  Hirohisa Kitagawa

发明人： Masahide Nakayama ,  Keiichi Tsuto ,  Takenori Hirano ,  Tsutomu Sakai ,  Ayato Kawashima ,  Hirohisa Kitagawa

IPC分类号： B01J23/00 ,  B01J23/02 ,  B01J23/04 ,  B01J23/34 ,  B01J23/83 ,  B01J37/03 ,  C07C67/03 ,  C11C3/04 ,  C11C3/10 ,  C11C3/00

CPC分类号： C11C3/10 ,  B01J23/002 ,  B01J23/02 ,  B01J23/04 ,  B01J23/34 ,  B01J23/83 ,  B01J37/03 ,  B01J2523/00 ,  C07C67/03 ,  C11C3/04 ,  Y02E50/13 ,  Y02P20/544 ,  C07C69/52 ,  C07C69/24 ,  B01J2523/15 ,  B01J2523/17 ,  B01J2523/25 ,  B01J2523/36 ,  B01J2523/24 ,  B01J2523/3706 ,  B01J2523/845 ,  B01J2523/23 ,  B01J2523/47 ,  B01J2523/72 ,  B01J2523/842

摘要： The present invention relates to a process for preparing an alkyl ester of a fatty acid wherein a transesterification reaction is carried out between a fat or oil and an alcohol in the presence of a catalyst comprising a composite metal oxide having a perovskite structure; and a process for preparing an alkyl ester of a fatty acid wherein a transesterification reaction is carried out between a fat or oil and an alcohol in the presence of a catalyst comprising at least one member selected from the group consisting of oxides, hydroxides and carbonates of alkaline earth metals is used as the catalyst, with the alcohol made into a supercritical state or subcritical state. According to the present invention, the alkyl ester of a fatty acid which can be effectively utilized as a diesel fuel oil or the like can be prepared at high efficiency and on an industrial scale mainly from triglyceride contained in a fat or oil, especially a waste oil.

摘要翻译： 本发明涉及一种制备脂肪酸烷基酯的方法，其中在包含具有钙钛矿结构的复合金属氧化物的催化剂存在下，在脂肪或油与醇之间进行酯交换反应; 以及一种制备脂肪酸烷基酯的方法，其中酯交换反应在脂肪或油与醇之间进行，所述催化剂包含至少一种选自氧化物，氢氧化物和碳酸酯的组分的催化剂 使用碱土金属作为催化剂，使醇成为超临界状态或亚临界状态。 根据本发明，能够有效地用作柴油燃料油等的脂肪酸的烷基酯可以以高效率和工业规模主要由脂肪或油中的甘油三酯，特别是废物 油。