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    ENZYME SUBSTRATE FOR LABELING OF PROTEIN
    1.
    发明申请
    ENZYME SUBSTRATE FOR LABELING OF PROTEIN 审中-公开
    用于标记蛋白质的酶基质

    公开(公告)号：US20110184147A1

    公开(公告)日：2011-07-28

    申请号：US13001929

    申请日：2009-07-03

    申请人： Noriho Kamiya ,  Masahiro Goto ,  Hiroki Abe

    发明人： Noriho Kamiya ,  Masahiro Goto ,  Hiroki Abe

    IPC分类号： C07K5/08 ,  C07K5/06 ,  C07K19/00 ,  C12P21/02

    CPC分类号： C07K1/13 ,  C07K5/06113 ,  G01N33/535

    摘要： The present invention provides a substrate of TGase represented by (fluorescent group)-(linker)-(a portion containing a Gln residue capable of recognition by transglutaminase (TGase))-R, wherein the fluorescent group is fluorescein isothiocyanate (FITC), Texas Red (TE) or dansyl (Dns) or a group derived therefrom; the linker is a group represented by —NH—(CH2)n—CO— (n is an integer of 1 to 6); the portion containing a Gln residue capable of recognition by TGase is a group derived from a peptide selected from among QG and the like; and R is a hydroxyl group, or biotin, nucleic acid, azide, alkyne, maleimide or cyclopentadiene, or a group derived therefrom.

    摘要翻译： 本发明提供由（荧光基团） - （接头） - （含有能够被转谷氨酰胺酶（TGase）识别的Gln残基的部分）-R表示的TGase的底物，其中荧光基团是异硫氰酸荧光素（FITC），得克萨斯 红（TE）或丹酰基（Dns）或衍生自其的基团; 接头是由-NH-（CH 2）n -CO-（n为1至6的整数）表示的基团。 含有能够通过TGase识别的Gln残基的部分是衍生自选自QG等的肽的基团; R为羟基，或生物素，核酸，叠氮化物，炔，马来酰亚胺或环戊二烯，或由其衍生的基团。

    Gaming machine with sound output for specific symbol and control method thereof
    2.
    发明授权
    Gaming machine with sound output for specific symbol and control method thereof 有权
    具有声音输出的游戏机具体符号及其控制方法

    公开(公告)号：US09378625B2

    公开(公告)日：2016-06-28

    申请号：US12566215

    申请日：2009-09-24

    申请人： Taihei Abe ,  Koutarou Moriyama ,  Toshiaki Ohkubo ,  Shigeki Hayashi ,  Yuka Hotta ,  Tsuyoshi Ohira ,  Hiroki Abe ,  Takanori Sakata

    发明人： Taihei Abe ,  Koutarou Moriyama ,  Toshiaki Ohkubo ,  Shigeki Hayashi ,  Yuka Hotta ,  Tsuyoshi Ohira ,  Hiroki Abe ,  Takanori Sakata

    IPC分类号： G07F17/34 ,  G07F17/32 ,  A63F13/54

    CPC分类号： G07F17/34 ,  A63F13/54 ,  A63F2300/6063 ,  G07F17/3227

    摘要： A slot machine has a display on which symbols are rearranged in partitioned regions arranged in multiple columns and rows. The display has multiple display windows corresponding to the respective columns for each unit game. In each of the display windows, symbols are rearranged by executing video display in which a symbol column having multiple symbols is scrolled in an arrangement direction of the symbols. When a symbol rearranged in at least one partitioned region in at least one of the symbol columns already stopped from scrolling forms a pattern just before winning combination establishment in which the rearranged symbol requires a specific symbol in at least one other symbol column in scrolling, a passing sound of the specific symbol is outputted from a speaker in synchronization with a timing at which the specific symbol in the symbol column in scrolling passes through the display window.

    摘要翻译： 老虎机具有显示器，其中符号被重新布置在以多列和多列排列的分区中。 显示器具有对应于每个单位游戏的各列的多个显示窗口。 在每个显示窗口中，通过执行其中具有多个符号的符号列在符号的排列方向上滚动的视频显示来重新排列符号。 当在已经从滚动停止的至少一个符号列中的至少一个划分区域中重新排列的符号在刚刚获胜组合建立之前形成模式，其中重新排列的符号在滚动中的至少一个其他符号列中需要特定符号， 与滚动中的符号列中的特定符号通过显示窗口的定时同步地从扬声器输出特定符号的通过声音。

    GLYCOPEPTIDE ARRAY
    4.
    发明申请
    GLYCOPEPTIDE ARRAY 审中-公开
    糖蛋白阵列

    公开(公告)号：US20130316932A1

    公开(公告)日：2013-11-28

    申请号：US13989023

    申请日：2011-11-22

    申请人： Shin-Ichiro Nishimura ,  Takahiko Matsushita ,  Hideyuki Shimaoka ,  Wataru Takada ,  Kohta Igarashi ,  Midori Abe ,  Hiroki Abe ,  Masao Fukushima

    发明人： Shin-Ichiro Nishimura ,  Takahiko Matsushita ,  Hideyuki Shimaoka ,  Wataru Takada ,  Kohta Igarashi ,  Midori Abe ,  Hiroki Abe ,  Masao Fukushima

    IPC分类号： G01N33/68

    CPC分类号： G01N33/6845 ,  G01N33/54353 ,  G01N33/54393 ,  G01N33/6842

    摘要： The present invention provides: a glycopeptide array which is useful for the detection of the binding between a substance to be detected and a glycopeptide; and an array which can inhibit the non-specific adsorption or binding of a substance to be detected without the need of coating any adsorption-inhibiting agent and which has the glycopeptide immobilized thereon. In the present invention, it was found that a glycopeptide that has a molecule having a carbonyl group bound to a peptide moiety thereof can be immobilized on a substrate that is coated with a polymer compound containing a unit having a primary amino group with high efficiency through the carbonyl group. Particularly, it was found by the present inventors that a glycopeptide can be immobilized on a substrate with high efficiency and the non-specific adsorption or binding of a substance to be detected can be inhibited effectively when a substrate that is coated with a polymer compound containing a unit having a primary amino group, a unit for retaining hydrophilicity and a unit having a hydrophobic group is used as the substrate for the glycopeptide.

    摘要翻译： 本发明提供：糖肽阵列，其可用于检测待检测物质与糖肽之间的结合; 以及可以抑制待检测物质的非特异性吸附或结合而不需要涂覆任何吸附抑制剂并且其上固定有糖肽的阵列。 在本发明中，发现具有与其肽部分结合的具有羰基的分子的糖肽可以固定在具有高分子量的高分子化合物的基材上，所述高分子化合物通过 羰基。 特别是本发明人发现，可以高效率地将糖肽固定在基材上，并且当涂布有含高分子化合物的基材时，能够有效地抑制待检测物质的非特异性吸附或结合 使用具有伯氨基的单元，用于保持亲水性的单元和具有疏水基团的单元作为糖肽的底物。

    Lens device and projector having diaphragm mechanisms with apertures having inwardly curved sides
    6.
    发明授权
    Lens device and projector having diaphragm mechanisms with apertures having inwardly curved sides 失效
    透镜装置和投影仪具有光阑机构，孔具有向内弯曲的侧面

    公开(公告)号：US07114815B2

    公开(公告)日：2006-10-03

    申请号：US11330100

    申请日：2006-01-12

    申请人： Hiroki Abe ,  Tomoo Fujimori ,  Motoo Takahashi ,  Kenji Samejima

    发明人： Hiroki Abe ,  Tomoo Fujimori ,  Motoo Takahashi ,  Kenji Samejima

    IPC分类号： G03B21/00 ,  G03B21/14 ,  G03B21/22 ,  G03B3/00 ,  G02F1/1335

    CPC分类号： H04N9/3105 ,  G02B13/22 ,  G03B21/142 ,  G03B21/2053 ,  H04N5/7416 ,  H04N9/3194

    摘要： The invention provides A lens device of a projector for projecting light that has been modulated and emitted by a display device, wherein said lens device has an optical axis and is arranged telecentric to rays of light emitted from said display device, said lens device has a diaphragm mechanism having an aperture at such a position that the lens device causes principal rays emitted from various locations on the display device to intersect with the optical axis; and said aperture is shaped such that sides of the aperture curve inward approximately along lines that connect areas having substantially similar levels of contrast.

    摘要翻译： 本发明提供一种投影仪的透镜装置，用于投影由显示装置调制和发射的光，其中所述透镜装置具有光轴并且被设置为远离所述显示装置发射的光线，所述透镜装置具有 所述光圈机构在所述透镜装置使得从所述显示装置上的各个位置发射的主光线与所述光轴相交的位置处具有孔; 并且所述孔被成形为使得孔的侧面大致沿着连接具有基本相似水平对比度的区域的线向内弯曲。

    LCD panel connector for use in connection between an LCD panel and a circuit board
    7.
    发明授权
    LCD panel connector for use in connection between an LCD panel and a circuit board 失效
    LCD面板连接器，用于LCD面板和电路板之间的连接

    公开(公告)号：US5888076A

    公开(公告)日：1999-03-30

    申请号：US938070

    申请日：1997-09-26

    申请人： Shigenori Itoh ,  Kazuaki Ibaraki ,  Yoshiaki Ishiyama ,  Hiroki Abe

    发明人： Shigenori Itoh ,  Kazuaki Ibaraki ,  Yoshiaki Ishiyama ,  Hiroki Abe

    IPC分类号： G02F1/13 ,  G09F9/35 ,  H01R12/70 ,  H01R12/71 ,  H01R12/83 ,  H01R9/09

    CPC分类号： G02F1/13452 ,  H01R12/7005 ,  H01R12/716 ,  H01R12/83

    摘要： An LCD panel (45) has a plurality of terminal electrodes (45d) formed at a peripheral portion thereof. The LCD panel (45) is brought into contact with conductive contact elements (13) and fixed by fixing means (71) to be electrically connected to a circuit board (81). An insulator (11) has a first surface (11a) for mounting the peripheral portion of the LCD panel (45), and a second surface (11b) to be faced to the circuit board (11b). The contact elements (13) are fixedly mounted in the insulator (11) to be brought into contact with the terminal electrodes (45d), respectively, when the LCD panel (45) is disposed on the first surface (11a) of the insulator (11). The fixing means (71) clamps and fixedly holds the insulator (11) and the LCD panel (45) when the LCD panel (45) is disposed on the first surface (11a). The insulator (11) is combined with a header (100) to be mounted on the circuit board (81).

    摘要翻译： LCD面板（45）具有形成在其周边部分的多个端子电极（45d）。 LCD面板（45）与导电接触元件（13）接触并由固定装置（71）固定，以电连接到电路板（81）。 绝缘体（11）具有用于安装LCD面板（45）的周边部分的第一表面（11a）和面向电路板（11b）的第二表面（11b）。 当LCD面板（45）设置在绝缘体的第一表面（11a）上时，接触元件（13）分别固定地安装在绝缘体（11）中以与端子电极（45d）接触 11）。 当LCD面板（45）设置在第一表面（11a）上时，固定装置（71）夹紧并固定住绝缘体（11）和LCD面板（45）。 绝缘体（11）与要安装在电路板（81）上的集管（100）组合。

    Sugar chain array
    9.
    发明授权
    Sugar chain array 有权
    糖链阵列

    公开(公告)号：US09310358B2

    公开(公告)日：2016-04-12

    申请号：US13812787

    申请日：2011-07-29

    申请人： Shin-Ichiro Nishimura ,  Takahiko Matsushita ,  Hideyuki Shimaoka ,  Wataru Takada ,  Kohta Igarashi ,  Midori Abe ,  Hiroki Abe ,  Masao Fukushima

    发明人： Shin-Ichiro Nishimura ,  Takahiko Matsushita ,  Hideyuki Shimaoka ,  Wataru Takada ,  Kohta Igarashi ,  Midori Abe ,  Hiroki Abe ,  Masao Fukushima

    IPC分类号： G01N33/53 ,  G01N33/543 ,  G01N33/66

    CPC分类号： G01N33/5308 ,  G01N33/54393 ,  G01N33/569 ,  G01N33/66 ,  G01N2333/42

    摘要： A sugar chain array containing a sugar chain immobilized thereon for detecting binding between an analyte and a sugar chain, and a sugar chain array having the sugar chain immobilized thereon that is capable of inhibiting non-specific adsorption and binding of an analyte without having to coat the array with an adsorption inhibitor. A specific sugar chain is immobilized on the array, and is useful for detecting binding between the sugar chain and an analyte, such as a pathogen of an infectious disease or an excretion thereof. In addition, in the array, when a base material is coated with a polymeric compound having a unit having a primary amino group, a unit for maintaining hydrophilicity, and a unit having a hydrophobic group, the sugar chain is immobilized efficiently and non-specific adsorption and binding of the analyte can be effectively inhibited.

    摘要翻译： 含有固定在其上用于检测分析物和糖链之间的结合的糖链的糖链阵列和其上固定有糖链的糖链阵列，其能够抑制分析物的非特异性吸附和结合而不必涂覆 该阵列带有吸附抑制剂。 特定的糖链固定在阵列上，并且可用于检测糖链和分析物之间的结合，例如感染性疾病的病原体或其排泄物。 此外，在阵列中，当用具有伯氨基单元的聚合化合物，保持亲水性的单元和具有疏水基团的单元涂覆基材时，糖链被有效且非特异性地固定 可以有效地抑制分析物的吸附和结合。