摘要:
Compounds of formula (I): ##STR1## (wherein: l is 2-4; A and B are oxygen or sulfur; one of R.sup.1 and R.sup.2 represents a long chain alkyl, alkylcarbamoyl or aliphatic acyl group and the other of R.sup.1 and R.sup.2 represents a group of formula (III) or (II.sub.f): ##STR2## in which E represents a single bond, a bivalent heterocyclic group or a group of formula --CO--, --COO-- or --CONR.sup.6 --, where R.sup.6 is hydrogen or an imino-protecting group; m is 0-3; n is 0-10; q is 0 or 1; R.sup.4 is optionally protected hydroxy, mercapto group or carboxy; Q is an amino or nitrogen-containing heterocyclic group;R.sub.f.sup.4 R.sub.f.sup.5 and R.sub.f.sup.6 are independently selected from the group consisting of hydrogen atoms and C.sub.1 -C.sub.6 alkyl groups, or R.sub.f.sup.4 and R.sub.f.sup.5 or R.sub.f.sup.4, R.sub.f.sup.5 and R.sub.f.sup.6, together with the nitrogen atom to which they are attached, form a heterocyclic ring) are PAF antagonists which may be used to treat asthma, hypotension, inflammation and shock. They may be prepared by reacting the corresponding compound having a haloalkyl phosphate ester or alkylenephosphate ester group in place of the ammonioalkyl phosphate ester group with an appropriate amine.
摘要翻译:式(I)化合物:其中:I为2-4; A和B为氧或硫; R 1和R 2中的一个为长链烷基,烷基氨基甲酰基或脂族酰基,另一个为 R 1和R 2表示式(III)或(IIf)的基团:其中E表示单键,二价杂环基或式-CO-的基团, - (IIf) - (IIf) COO-或-CONR 6 - ,其中R 6为氢或亚氨基保护基; m为0-3; n为0-10; q为0或1; R 4为任选保护的羟基,巯基或羧基; Q为 氨基或含氮杂环基; Rf4Rf5和Rf6独立地选自氢原子和C1-C6烷基,或Rf4和Rf5或Rf4,Rf5和Rf6与它们所连接的氮原子一起 ,形成杂环)是可用于治疗哮喘,低血压,炎症和休克的PAF拮抗剂。 它们可以通过使具有卤代烷基磷酸酯或亚烷基磷酸酯基团的相应化合物代替磷酸烷基酯基团与适当的胺反应来制备。
摘要:
Compounds of formula (I): ##STR1## [wherein: m is 1-3; A and B are oxygen or sulfur; and one of R.sup.1 and R.sup.2 is C.sub.10 -C.sub.22 alkyl and the other is a group of formula (II). ##STR2## where: n is 2 or 3; and --NR.sup.3 R.sup.4 R.sup.5 is an amino group] and salts thereof are effective anti-cancer agents.
摘要翻译:式(I)的化合物:其中:m为1-3; A和B是氧或硫; 并且R 1和R 2中的一个是C 10 -C 22烷基,另一个是式(II)的基团。 (II)其中:n为2或3; 和-NR 3 R 4 R 5是氨基],其盐是有效的抗癌剂。
摘要:
The main object of the invention is to provide an electromagnetic wave resonator making use of surface waves: an electromagnetic wave resonator structure capable of being achieved with existing technologies yet without much difficulty and applying voltage to a positive dielectric area, thereby overcoming a variety of problems arising from the fact that only thermal excitation is available.The contact structure of negative dielectric/positive dielectric/negative dielectric necessary for this type of electromagnetic wave resonator is provided on the surface of the negative dielectric material 1 just as the coaxial structure of the positive dielectric thin film 3 extending in the Y-axis direction and the negative dielectric material 2 received therein is cut in the axial direction. This makes sure both negative dielectric materials 1 and 2 with the positive dielectric thin film 3 sandwiched between them are electrically insulated so that voltage can be applied to the positive dielectric thin film 3, and ensures that an area provided in the negative dielectric material 1 to receive the positive dielectric thin film 3 has an aspect ratio D/P1 of about 1.9, a figure well achievable in the state of the art.
摘要:
The present invention provides an electromagnetic wave resonator that is capable of showing surface wave resonance typically as outstanding plasmon resonance and can be manufactured industrially with excellent reproducibility and efficiency by combining currently available microprocessing technologies. The electromagnetic wave resonator of the present invention includes a first negative dielectric surface, a second negative dielectric surface and a positive dielectric thin film disposed between the first and the second negative dielectric surfaces. The positive dielectric thin film has an end face having an electromagnetic wave introduced therefrom. Intensity of the electromagnetic wave having a predetermined wavelength and being introduced from the end face is enhanced in the electromagnetic wave resonator due to resonance of a surface wave having an electric field component in a direction of film thickness of the positive dielectric thin film and without having a cut-off frequency.
摘要:
A power control apparatus for controlling charging and discharging of a plurality of storage devices, including a voltage measuring device for measuring voltages of the storage devices, a current measuring device for measuring currents flowing through the storage devices, a status detecting device for detecting the operating status of each of the storage devices from values measured by the voltage measuring device and the current measuring device, and a charging/discharging controlling device for controlling currents, voltages, or power according to the operating status of each storage device detected by the status detecting device to charge or discharge the storage devices.
摘要:
Lower order control devices control plural battery cells configuring plural battery modules. An input terminal of the low order control device in the highest potential, an output terminal of the low order control device in the lowest potential, and a high order control device are connected by isolating units, photocouplers. Diodes which prevent a discharge current of the battery cells in the battery modules are disposed between the output terminal of the low order control device and the battery cells in the battery module on the low potential side. Terminals related to input/output of a signal are electrically connected without isolating among the plural low order control devices.
摘要:
An optical connector 1 includes a plastic ferrule 4 that holds optical fibers 7, a plastic holder member 61 that holds the ferrule 4, a plastic plug 6 that is arranged outside the holder member 61, and a metal intermediate member 5 that is disposed between an outer surface of the holder member 61 and an inner surface of the plug 6.
摘要:
Lower order control devices control plural battery cells configuring plural battery modules. An input terminal of the low order control device in the highest potential, an output terminal of the low order control device in the lowest potential, and a high order control device are connected by isolating units, photocouplers. Diodes which prevent a discharge current of the battery cells in the battery modules are disposed between the output terminal of the low order control device and the battery cells in the battery module on the low potential side. Terminals related to input/output of a signal are electrically connected without isolating among the plural low order control devices.
摘要:
An optical connector 10 includes a ferrule 20 to secure the set of multiple optical fibers 100, a plug member 21 to hold the ferrule 20, and a spacer 22 having a pin 23 for guiding, the spacer being integrally fixed to the ferrule 20 by means of inserting the pin 23 into the ferrule 20 to be secured together with the ferrule within the plug member 21, wherein the ferrule 20 has at least one first positioning portion for example a recessed portion 51, 52, and the spacer 22 has at least one second positioning portion for example a projection 61, 62 which is fitted to a corresponding first positioning portion to position the ferrule to the spacer.
摘要:
Lower order control devices control plural battery cells configuring plural battery modules. An input terminal of the low order control device in the highest potential, an output terminal of the low order control device in the lowest potential, and a high order control device are connected by isolating units, photocouplers. Diodes which prevent a discharge current of the battery cells in the battery modules are disposed between the output terminal of the low order control device and the battery cells in the battery module on the low potential side. Terminals related to input/output of a signal are electrically connected without isolating among the plural low order control devices.