摘要:
An inducer of cytotoxic T cells comprising as an active ingredient a protein which comprises the same or substantially the same amino acid sequence as that shown in SEQ ID NO: 2, or a peptide derived from the protein above is provided.
摘要翻译:提供包含作为活性成分的包含与SEQ ID NO:2所示相同或基本相同的氨基酸序列的蛋白质或来自上述蛋白质的肽的细胞毒性T细胞的诱导剂。
摘要:
An inducer of cytotoxic T cells comprising as an active ingredient a protein which comprises the same or substantially the same amino acid sequence as that shown in SEQ ID NO: 2, or a peptide derived from the protein above is provided.
摘要翻译:提供包含作为活性成分的包含与SEQ ID NO:2所示相同或基本相同的氨基酸序列的蛋白质或来自上述蛋白质的肽的细胞毒性T细胞的诱导剂。
摘要:
An inducer of cytotoxic T cells comprising as an active ingredient a protein which comprises the same or substantially the same amino acid sequence as that shown in SEQ ID NO: 2, or a peptide derived from the protein above is provided.
摘要翻译:提供包含作为活性成分的包含与SEQ ID NO:2所示相同或基本相同的氨基酸序列的蛋白质或来自上述蛋白质的肽的细胞毒性T细胞的诱导剂。
摘要:
Disclosed is a peptide consisting of the identical amino acid sequence or a substantially identical amino acid sequence to the amino acid sequence depicted in SEQ ID NO:4, wherein the peptide binds to an HLA antigen and is recognized by cytotoxic T cells. The peptide of the present invention can be used in vivo or in vitro as an agent for inducing CTL, that is, cancer vaccine, and exerts therapeutic or ameliorating effects on tumors such as osteosarcoma, renal cancer, and others. The peptide of the present invention is also useful as a tumor marker directed to tumors such as sarcoma, renal cancer, and others.
摘要翻译:公开了由与SEQ ID NO:4所示的氨基酸序列相同的氨基酸序列或基本相同的氨基酸序列组成的肽,其中所述肽结合HLA抗原并被细胞毒性T细胞识别。 本发明的肽可以在体内或体外用作诱导CTL的药剂,即癌症疫苗,对骨肉瘤,肾癌等肿瘤发挥治疗或改善作用。 本发明的肽也可用作针对诸如肉瘤,肾癌等肿瘤的肿瘤标志物。
摘要:
Disclosed is a peptide consisting of the identical amino acid sequence or a substantially identical amino acid sequence to the amino acid sequence depicted in SEQ ID NO:4, wherein the peptide binds to an HLA antigen and is recognized by cytotoxic T cells. The peptide of the present invention can be used in vivo or in vitro as an agent for inducing CTL, that is, cancer vaccine, and exerts therapeutic or ameliorating effects on tumors such as osteosarcoma, renal cancer, and others. The peptide of the present invention is also useful as a tumor marker directed to tumors such as sarcoma, renal cancer, and others.
摘要翻译:公开了由与SEQ ID NO:4所示的氨基酸序列相同的氨基酸序列或基本相同的氨基酸序列组成的肽,其中所述肽结合HLA抗原并被细胞毒性T细胞识别。 本发明的肽可以在体内或体外用作诱导CTL的药剂,即癌症疫苗,对骨肉瘤,肾癌等肿瘤发挥治疗或改善作用。 本发明的肽也可用作针对诸如肉瘤,肾癌等肿瘤的肿瘤标志物。
摘要:
In order to provide a composition for treating, improving, or preventing pain, it has been found out that a metallothionein protein is expressed in a normal peripheral nerve, and that the expression is not observed in a peripheral nerve producing pain. Moreover, it has been found out that administering metallothionein to rats having neuropathic pain suppresses the pain in the rats.
摘要:
A taste improving agent for food and beverage containing potassium chloride that can effectively relieve unpleasant tastes, such as bitter taste and harsh taste, attributed to potassium chloride without detriment to the flavor of the food and beverage; a process for producing a food and beverage containing potassium chloride of high palatability having the bitter taste and harsh taste of potassium chloride suppressed; and a food and beverage containing potassium chloride produced by the production process. Use is made of a taste improving agent comprising a basic amino acid and/or a basic peptide as an active ingredient. It is preferred that the basic amino acid be at least one member selected from among histidine, arginine and lysine and the basic peptide at least one member selected from among anserine, carnosine and balenine. This taste improving agent is added to a food and beverage containing potassium chloride, thereby obtaining a food and beverage containing potassium chloride with improved taste.
摘要:
In order to provide a composition for treating, improving, or preventing pain, it has been found out that a metallothionein protein is expressed in a normal peripheral nerve, and that the expression is not observed in a peripheral nerve producing pain. Moreover, it has been found out that administering metallothionein to rats having neuropathic pain suppresses the pain in the rats.