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公开(公告)号：US11850246B2
公开(公告)日：2023-12-26
申请号：US17393587
申请日：2021-08-04
Applicant: NOVMETAPHARMA CO., LTD.
Inventor： In-Kyu Lee , Jae-Han Jeon , Dipanjan Chanda , Eun Jung Choi , Hoe-Yune Jung , Heon Jong Lee
IPC: A61K31/495 , A61P29/00
CPC classification number: A61K31/495
Abstract: A composition for preventing and/or treating cytokine release syndrome and a method of prevention and/or treatment of cytokine release syndrome are disclosed. The composition includes an aryl ethene compound, a pharmaceutically acceptable salt thereof, or a solvate thereof, as an active ingredient. The method includes administering the aryl ethene compound, an isomer, a pharmaceutically acceptable salt thereof, or a solvate thereof, in an effective amount to a subject in need thereof. The cytokine release syndrome may be caused by virulent infection. The administration of the compound reduces the pre-inflammatory cytokine levels in the subject.
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公开(公告)号：US11547737B2
公开(公告)日：2023-01-10
申请号：US17350170
申请日：2021-06-17
Applicant: NovMetaPharma Co., Ltd.
Inventor： Hoe-Yune Jung , Heonjong Lee , Dohyun Lee
IPC: A61K38/05 , A61K31/685 , A61K31/56 , A61K31/315
Abstract: Compositions and methods for treating viral infection are disclosed. The compositions contain a combination of zinc and a cyclo(His-Pro), in effective amounts. The composition containing a combination of zinc and a cyclo(His-Pro) can be used to treat viral infections including SARS-CoV-2 infections in mammals.
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公开(公告)号：US20210100872A1
公开(公告)日：2021-04-08
申请号：US16956109
申请日：2018-12-11
Applicant: Novmetapharma Co., Ltd.
Inventor： Heon Jong Lee , Kay Olmstead , Moon Ki Song , Kyong-Tai Kim , In-Kyu Lee , Hoe-Yune Jung
Abstract: The present invention relates to a pharmaceutical formulation for preventing or treating diabetes mellitus, comprising cyclo-hispro as an active ingredient. Specifically, the present invention has the effect of lowering the concentration of glycated hemoglobin (HbA1c) in the blood, and further improving leptin resistance. In addition, the present invention relates to a pharmaceutical formulation for preventing or treating diabetes mellitus, characterized in that the pharmaceutical formulation comprises cyclo-hispro and zinc and is administered once a day.
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公开(公告)号：US11433114B2
公开(公告)日：2022-09-06
申请号：US17172879
申请日：2021-02-10
Applicant: NovMetaPharma Co., Ltd.
Inventor： Hoe-Yune Jung , Heon-Jong Lee , Jong-Su Jeon , Yon-Su Kim , Seung-Hee Yang , Yong-Chul Kim , Jong-Joo Moon , Hwan-Soo Yoo , Kyeong-Mi Choi
Abstract: A new use of a cyclo histidine-proline (Cyclo His-Pro, CHP) is disclosed. A composition including cyclo histidine-proline (CHP) as an active ingredient has an excellent protective effect to protect kidney and liver cells from damage and/or toxicity induced by various causes. The composition is useful and effective in protecting kidney and/or liver cells/tissues and in treating a subject with kidney and/or liver diseases and/or damages.
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Patent Agency Ranking
公开(公告)号：US20210401880A1
公开(公告)日：2021-12-30
申请号：US17292238
申请日：2019-11-05
Applicant: Novmetapharma Co., Ltd.
Inventor： Heon Jong Lee , Kay Olmstead , Moon Ki Song , Kyong-Tai Kim , In-Kyu Lee , Hoe-Yune Jung
Abstract: The present invention relates to a pharmaceutical composition for preventing or treating obesity, comprising cyclo-hispro as an active ingredient. Specifically, the present invention has the effect of reducing body weight and body mass, and further improving leptin resistance. In addition, the present invention relates to a pharmaceutical composition for preventing or treating obesity, characterized in that the pharmaceutical composition comprises cyclo-hispro and zinc and is administered once a day.
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公开(公告)号：US11890317B2
公开(公告)日：2024-02-06
申请号：US17856729
申请日：2022-07-01
Applicant: NovMetaPharma Co., Ltd.
Inventor： Hoe-Yune Jung , Heon-Jong Lee , Jong-Su Jeon , Yon-Su Kim , Seung-Hee Yang , Yong-Chul Kim , Jong-Joo Moon , Hwan-Soo Yoo , Kyeong-Mi Choi
CPC classification number: A61K38/12 , A23L33/00 , A23L33/18 , A61K38/05 , A61P31/00 , A61P35/00 , C07K5/12 , A23V2002/00 , A23V2200/308 , A23V2250/55 , A61P1/16 , A61K38/12 , A61K2300/00
Abstract: A new use of a cyclo histidine-proline (Cyclo His-Pro, CHP) is disclosed. A composition including cyclo histidine-proline (CHP) as an active ingredient has an excellent protective effect to protect kidney and liver cells from damage and/or toxicity induced by various causes. The composition is useful and effective in protecting kidney and/or liver cells/tissues and in treating a subject with kidney and/or liver diseases and/or damages.
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公开(公告)号：US20210161998A1
公开(公告)日：2021-06-03
申请号：US17172879
申请日：2021-02-10
Applicant: NovMetaPharma Co., Ltd.
Inventor： Hoe-Yune Jung , Heon-Jong Lee , Jong-Su Jeon , Yon-Su Kim , Seung-Hee Yang , Yong-Chul Kim , Jong-Joo Moon , Hwan-Soo Yoo , Kyeong-Mi Choi
Abstract: A new use of a cyclo histidine-proline (Cyclo His-Pro, CHP) is disclosed. A composition including cyclo histidine-proline (CHP) as an active ingredient has an excellent protective effect to protect kidney and liver cells from damage and/or toxicity induced by various causes. The composition is useful and effective in protecting kidney and/or liver cells/tissues and in treating a subject with kidney and/or liver diseases and/or damages.
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公开(公告)号：US10918693B2
公开(公告)日：2021-02-16
申请号：US16316595
申请日：2017-07-13
Applicant: NOVMETAPHARMA CO., LTD.
Inventor： Hoe-Yune Jung , Heon-Jong Lee , Jong-Su Jeon , Yon-Su Kim , Seung-Hee Yang , Yong-Chul Kim , Jong-Joo Moon , Hwan-Soo Yoo , Kyeong-Mi Choi
Abstract: The present disclosure relates to a cell-protecting pharmaceutical composition including a cyclo histidine-proline (Cyclo His-Pro, CHP) as an active ingredient. The cell-protecting pharmaceutical composition including the present cyclo histidine-proline (CHP) as an active ingredient has an excellent protective effect to protect kidney and liver cells from toxicity. Thus, the composition may be useful for the prevention or treatment of kidney and liver diseases.
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9.发明申请公开(公告)号：US20190290720A1
公开(公告)日：2019-09-26
申请号：US16316595
申请日：2017-07-13
Applicant: NOVMETAPHARMA CO., LTD.
Inventor： Hoe-Yune Jung , Heon-Jong Lee , Jong-Su Jeon , Yon-Su Kim , Seung-Hee Yang , Yong-Chul Kim , Jong-Joo Moon , Hwan-Soo Yoo , Kyeong-Mi Choi
Abstract: The present disclosure relates to a cell-protecting pharmaceutical composition including a cyclo histidine-proline (Cyclo His-Pro, CHP) as an active ingredient. The cell-protecting pharmaceutical composition including the present cyclo histidine-proline (CHP) as an active ingredient has an excellent protective effect to protect kidney and liver cells from toxicity. Thus, the composition may be useful for the prevention or treatment of kidney and liver diseases.
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