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公开(公告)号：US20170259011A1
公开(公告)日：2017-09-14
申请号：US15509899
申请日：2015-09-14
申请人： Novo Nordisk A/S
摘要： The present invention relates to a torsion spring driven injection device for delivering set doses of a liquid drug. The injection device mechanism is encapsulated in a housing which also stores the cartridge containing the liquid drug. A needle cannula which is in liquid communication with the interior of the cartridge and which has a distal tip is shielded by a telescopically movable needle shield is used to inject the set dose. The needle cannula is preferably used for multiple injections and cleaned between subsequent injections. The drive mechanism further comprises a nut member engaging the piston rod and releasable coupled to the housing to operate as a pressure relief mechanism. The telescopically movable needle shield covering the distal tip of the needle cannula is formed to lock the nut member to the housing during injection.
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公开(公告)号：US20210346594A1
公开(公告)日：2021-11-11
申请号：US17382536
申请日：2021-07-22
申请人： Novo Nordisk A/S
发明人： Mie Haraldsted , Morten Revsgaard Frederiksen , Matias Melander , Christian Hoejris Nielsen , Graham Hinde , Bas Kamp , Roshan Hakkim
摘要： The invention relates to an injection device for injecting a liquid drug. The injection device comprises a housing assembly supporting a non-removable cartridge having an interior chamber containing the liquid drug to be injected and a reusable needle cannula connected to the cartridge. A needle shield assembly provided with a cleaning chamber containing a volume of a cleaning agent for cleaning at least the distal tip of the needle cannula between subsequent injections is further provided. The needle shield assembly is axially movable in a proximal direction in relation to the housing assembly from a first position to a second position upon rotation of at least a part of the needle shield assembly, wherein the first position is a position in which the distal tip of the needle cannula is located inside the cleaning chamber thereby cleansing the distal tip of the needle cannula, and the second position is a position in which the distal tip of the needle cannula is located outside and distal to the cleaning chamber for equalizing the pressure in the cartridge.
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公开(公告)号：US09750892B2
公开(公告)日：2017-09-05
申请号：US14667890
申请日：2015-03-25
申请人： Novo Nordisk A/S
发明人： Bo Radmer , Christian Plambech , Christian Hoejris Nielsen , Jesper Peter Windum , Tom Hede Markussen
CPC分类号： A61M5/3202 , A61M5/002 , A61M5/2466 , A61M2005/3117
摘要： The present invention relates to injection devices for injecting a dose of a medicament. The injection device (100) incorporates a housing (101), a needle assembly (150) and a cover (200). The needle assembly (150) comprises an injection needle (152,153) accommodated in a needle container (151) having an opening which in a storage state of the injection device (100) is sealed by a film seal (155). The cover may include sections (201,202) arranged movable relative to the housing (101). The injection device (100) is so configured that upon movement of the cover sections (201,202) relative to the housing (101) the film seal (155) is changed from a sealing state to an unsealing state for shifting the injection device (100) into a ready-to-administer state.
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公开(公告)号：US10350369B2
公开(公告)日：2019-07-16
申请号：US15108887
申请日：2014-12-16
申请人： Novo Nordisk A/S
摘要： The present invention relates to an injection apparatus for injecting a pharmaceutical liquid drug into the skin of a user. The injection apparatus can be in form of an injection device carrying a needle cannula or in the shape of a needle assembly (10) attachable to an injection device. The outer shell of the injection apparatus is a protective shield (10) divided into different segments (10a, 10b). These segments are preferably spaced from each other in the longitudinal direction to move individually in the axial direction. Further, the segments are provided with tilting means (14, 15) which are activated to move neighboring segments (10a, 10b) apart upon relative axial movement of one or more segments (10a, 10b) whenever an uneven force is applied to the distal end of the shield.
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5.发明授权公开(公告)号：US10335536B2
公开(公告)日：2019-07-02
申请号：US15310008
申请日：2015-05-08
申请人： Novo Nordisk A/S
摘要： Disclosed is a medical injection device (1) comprising a needle assembly (20) having a cannula (21) and a telescopic shield (30) for covering the distal tip (23) in a no use situation. The telescopic shield further carries a cleaning reservoir (40) for cleaning the needle cannula between two subsequent injections. The cleaning reservoir is provided with an opening (43) connecting to an overflow reservoir (51/55) such that the cleaning liquid contained in the cleaning reservoir can retract and expand upon temperature changes and does not enter the needle lumen instead. In one example, the overflow reservoir is formed as a channel (51).
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公开(公告)号：US10080848B2
公开(公告)日：2018-09-25
申请号：US15035563
申请日：2014-11-12
申请人： Novo Nordisk A/S
CPC分类号： A61M5/36 , A61M5/20 , A61M5/2033 , A61M5/2466 , A61M5/30 , A61M5/3146 , A61M5/31536 , A61M5/31553 , A61M5/31568 , A61M5/31573 , A61M5/31583 , A61M5/31585 , A61M2005/208 , A61M2005/2474 , A61M2005/3126 , A61M2205/502
摘要： The present invention provides a drug delivery device (1) comprising a dose delivery mechanism and a blocking structure (80, 180) for preventing inadvertent activation of the dose delivery mechanism. The blocking structure (80,180) enables and disables the dose delivery mechanism dependent on the position of a needle holder (30, 130) relative to a drug cartridge holder (20, 120).
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公开(公告)号：US20180243498A1
公开(公告)日：2018-08-30
申请号：US15754332
申请日：2016-08-10
申请人： Novo Nordisk A/S
发明人： Mie Haraldsted , Morten Revsgaard Frederiksen , Matias Melander , Christian Hoejris Nielsen , Graham Hinde , Bas Kamp , Roshan Hakkim
CPC分类号： A61M5/001 , A61M5/286 , A61M5/31573 , A61M5/3257 , A61M5/326 , A61M5/3271 , A61M2005/2073 , A61M2005/3267 , A61M2005/3284
摘要： The invention relates to an injection device for injecting a liquid drug. The injection device comprises a housing assembly supporting a non-removable cartridge having an interior chamber containing the liquid drug to be injected and a reusable needle cannula connected to the cartridge. A needle shield assembly provided with a cleaning chamber containing a volume of a cleaning agent for cleaning at least the distal tip of the needle cannula between subsequent injections is further provided. The needle shield assembly is axially movable in a proximal direction in relation to the housing assembly from a first position to a second position upon rotation of at least a part of the needle shield assembly, wherein the first position is a position in which the distal tip of the needle cannula is located inside the cleaning chamber thereby cleansing the distal tip of the needle cannula, and the second position is a position in which the distal tip of the needle cannula is located outside and distal to the cleaning chamber for equalizing the pressure in the cartridge.
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公开(公告)号：US11097046B2
公开(公告)日：2021-08-24
申请号：US15754332
申请日：2016-08-10
申请人： Novo Nordisk A/S
发明人： Mie Haraldsted , Morten Revsgaard Frederiksen , Matias Melander , Christian Hoejris Nielsen , Graham Hinde , Bas Kamp , Roshan Hakkim
摘要： The invention relates to an injection device for injecting a liquid drug. The injection device comprises a housing assembly supporting a non-removable cartridge having an interior chamber containing the liquid drug to be injected and a reusable needle cannula connected to the cartridge. A needle shield assembly provided with a cleaning chamber containing a volume of a cleaning agent for cleaning at least the distal tip of the needle cannula between subsequent injections is further provided. The needle shield assembly is axially movable in a proximal direction in relation to the housing assembly from a first position to a second position upon rotation of at least a part of the needle shield assembly, wherein the first position is a position in which the distal tip of the needle cannula is located inside the cleaning chamber thereby cleansing the distal tip of the needle cannula, and the second position is a position in which the distal tip of the needle cannula is located outside and distal to the cleaning chamber for equalizing the pressure in the cartridge.
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公开(公告)号：US10596329B2
公开(公告)日：2020-03-24
申请号：US15509899
申请日：2015-09-14
申请人： Novo Nordisk A/S
摘要： The present invention relates to a torsion spring driven injection device for delivering set doses of a liquid drug. The injection device mechanism is encapsulated in a housing which also stores the cartridge containing the liquid drug. A needle cannula which is in liquid communication with the interior of the cartridge and which has a distal tip is shielded by a telescopically movable needle shield is used to inject the set dose. The needle cannula is preferably used for multiple injections and cleaned between subsequent injections. The drive mechanism further comprises a nut member engaging the piston rod and releasable coupled to the housing to operate as a pressure relief mechanism. The telescopically movable needle shield covering the distal tip of the needle cannula is formed to lock the nut member to the housing during injection.
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公开(公告)号：US10213563B2
公开(公告)日：2019-02-26
申请号：US15528702
申请日：2015-11-23
申请人： Novo Nordisk A/S
IPC分类号： A61M5/32
摘要： The invention relates to an injection device for self-administration of doses of a liquid drug. The injection device carries a needle cannula (15) which is concealed by a telescopically movable shield (20). Further a stopping means (30) interconnects the shield with the helical rotatable scale sleeve (25) such that the shield can only be operated proximally when the scale sleeve is rotated away from its zero position. Once the scale sleeve returns to its zero position during expelling of the dose, the shield and the stopping means is allowed to slide distally and thus return to the locked position.
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