公开(公告)号：US20180179505A1

公开(公告)日：2018-06-28

申请号：US15885244

申请日：2018-01-31

Applicant: Novozymes, Inc. ,  Novozymes A/S

Inventor： Nikolaj Spodsberg ,  Brett McBrayer ,  Pierre Cassland

IPC: C12N9/42

CPC classification number: C12N9/2437 ,  C12Y302/01004

Abstract: The present invention relates to isolated polypeptides having endoglucanase activity, catalytic domains, cellulose binding domains and polynucleotides encoding the polypeptides, catalytic domains or cellulose binding domains. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains or cellulose binding domains.

公开(公告)号：US20170283843A1

公开(公告)日：2017-10-05

申请号：US15508631

申请日：2015-09-04

Applicant: Novozymes A/S

Inventor： Peter Westh ,  Kim Borch ,  Trine Soerensen ,  Michael Windahl ,  Brett McBrayer

IPC: C12P19/14 ,  C12N15/82 ,  C12P19/02 ,  C12P5/02 ,  C12P7/14 ,  C12P7/20 ,  C12P7/18 ,  C12N9/42 ,  C12P7/16

CPC classification number: C12P19/14 ,  C07K2319/00 ,  C12N9/2437 ,  C12N15/8257 ,  C12P5/02 ,  C12P7/14 ,  C12P7/16 ,  C12P7/18 ,  C12P7/20 ,  C12P19/02 ,  C12P2203/00 ,  C12Y302/01091

Abstract: The present invention relates to cellobiohydrolase variants and carbohydrate binding module variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

公开(公告)号：US20170166939A1

公开(公告)日：2017-06-15

申请号：US15039019

申请日：2014-11-25

Applicant: Novozymes A/S

Inventor： Paul Harris ,  Suchindra Maiyuran ,  Brett McBrayer ,  Gloria Muzzi-Erichsen

IPC: C12P19/14 ,  C12P19/02 ,  C12P21/02 ,  C12N9/42 ,  C12N9/24

CPC classification number: C12P19/14 ,  C12N9/2402 ,  C12N9/2437 ,  C12N9/2445 ,  C12N9/248 ,  C12N9/2482 ,  C12P19/02 ,  C12P21/02 ,  C12P2203/00 ,  C12Y302/01004 ,  C12Y302/01008 ,  C12Y302/01021 ,  C12Y302/01037 ,  C12Y302/01091

Abstract: The present invention relates to enzyme compositions and methods of producing and using the compositions for the saccharification of lignocellulosic material.

公开(公告)号：US20170145395A1

公开(公告)日：2017-05-25

申请号：US15377206

申请日：2016-12-13

Applicant: Novozymes, Inc. ,  Novozymes A/S

Inventor： Elena Vlasenko ,  Brett McBrayer ,  Dominique Skovlund ,  Sara Landvik

IPC: C12N9/42

CPC classification number: C12N9/2434 ,  C12N9/2462 ,  C12Y302/01008 ,  Y02E50/16 ,  Y02E50/17

Abstract: The present invention relates to isolated polypeptides having xylanase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.

公开(公告)号：US20170037389A1

公开(公告)日：2017-02-09

申请号：US15299974

申请日：2016-10-21

Applicant: NOVOZYMES A/S ,  NOVOZYMES, INC.

Inventor： Mary Ann Stringer ,  Brett McBrayer

IPC: C12N9/42 ,  C12P19/02 ,  C12P19/14 ,  C12N15/113 ,  C07K7/08

CPC classification number: C12N9/2437 ,  C07K7/08 ,  C07K2319/02 ,  C12N15/1137 ,  C12N2310/14 ,  C12N2310/141 ,  C12P19/02 ,  C12P19/14 ,  C12P2203/00 ,  C12Y302/01091 ,  C12Y302/01176

Abstract: The present invention relates to isolated polypeptides having cellobiohydrolase activity, catalytic domains, and cellulose binding domains and polynucleotides encoding the polypeptides, catalytic domains, and cellulose binding domains. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains, or cellulose binding domains.

Abstract translation: 本发明涉及具有纤维二糖水解酶活性的分离的多肽，催化结构域和纤维素结合结构域以及编码多肽，催化结构域和纤维素结合结构域的多核苷酸。 本发明还涉及包含多核苷酸的核酸构建体，载体和宿主细胞以及产生和使用多肽，催化结构域或纤维素结合结构域的方法。

公开(公告)号：US20150210991A1

公开(公告)日：2015-07-30

申请号：US14429241

申请日：2013-09-19

Applicant: NOVOZYMES, INC. ,  NOVOZYMES A/S

Inventor： Kirk Schnorr ,  Tarana Shaghasi ,  Brett McBrayer

IPC: C12N9/42 ,  C12P19/02 ,  C12P19/14

CPC classification number: C12N9/2437 ,  C12P7/10 ,  C12P19/02 ,  C12P19/14 ,  C12P2201/00 ,  C12P2203/00 ,  C12Y302/01004 ,  Y02E50/16

Abstract: The present invention relates to processes for degrading a cellulosic material and for producing substances from the cellulosic material using recombinant glycoside hydrolase of family 61 (GH61) from Trichoderma.

Abstract translation: 本发明涉及使用来自木霉属的61族（GH61）重组糖苷水解酶降解纤维素材料和从纤维素材料生产物质的方法。

公开(公告)号：US20230012672A1

公开(公告)日：2023-01-19

申请号：US17642925

申请日：2020-09-16

Applicant: Novozymes A/S

Inventor： Hong Zhi Huang ,  Jiyin Liu ,  Hui Xu ,  Elena Vlasenko ,  Brett McBrayer ,  Ye Liu ,  Lan Tang ,  James Ron Huffman ,  Nikolaj Spodsberg

IPC: C12N9/24 ,  C12N1/18 ,  C12N15/81 ,  C12P7/06

Abstract: The present invention relates to isolated polypeptides having beta-glucanase activity, catalytic domains, carbohydrate binding modules and polynucleotides encoding the polypeptides, catalytic domains or carbohydrate binding modules. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains or carbohydrate binding modules. The present invention further relates to processes for producing fermentation products from starch-containing or cellulosic-containing material, as well as an enzyme blend or composition, or a recombinant host cell or fermenting organism suitable for use in processes of the invention.

公开(公告)号：US10676769B2

公开(公告)日：2020-06-09

申请号：US15509659

申请日：2015-09-08

Applicant: Novozymes A/S

Inventor： Peter Westh ,  Kim Borch ,  Trine Soerensen ,  Michael Windahl ,  Brett McBrayer

IPC: C12P19/14 ,  C12N9/42 ,  C12N9/24 ,  C12N15/82 ,  C12P7/14 ,  C12P19/02 ,  C12P19/12

Abstract: The present invention relates to cellobiohydrolase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

公开(公告)号：US20170145397A1

公开(公告)日：2017-05-25

申请号：US15419609

申请日：2017-01-30

Applicant: NOVOZYMES A/S

Inventor： Brett McBrayer ,  Nikolaj Spodsberg

IPC: C12N9/24 ,  C12P19/14

CPC classification number: C12N9/2482 ,  C07K2319/02 ,  C12P19/02 ,  C12P19/12 ,  C12P19/14 ,  C12Y302/01008

Abstract: The present invention relates to isolated polypeptides having xylanase activity, catalytic domains, carbohydrate binding modules and polynucleotides encoding the polypeptides, catalytic domains or carbohydrate binding modules. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains or carbohydrate binding modules.

公开(公告)号：US20150353907A1

公开(公告)日：2015-12-10

申请号：US14832485

申请日：2015-08-21

Applicant: Novozymes A/S ,  Novozymes, Inc.

Inventor： Katja Salomon Johansen ,  Feng Xu ,  Paul Walton ,  Brett McBrayer ,  Henrik Lund ,  Chee-Leong Soong

IPC: C12N9/42

CPC classification number: C12N9/2437 ,  C12N9/2434 ,  C12N9/2477 ,  C12N9/96 ,  C12P7/10 ,  C12P7/14 ,  C12P19/02 ,  C12P19/04 ,  C12P2201/00 ,  C12P2203/00 ,  C12Y302/01004 ,  Y02E50/16 ,  Y02P20/52

Abstract: The present invention relates to methods of increasing the activity of a GH61 polypeptide having cellulolytic enhancing activity, comprising: adding a divalent copper cation to a composition comprising the GH61 polypeptide having cellulolytic enhancing activity, wherein the presence of the divalent copper cation and the GH61 polypeptide having cellulolytic enhancing activity increases degradation or conversion of a cellulosic material by an enzyme composition compared to the GH61 polypeptide having cellulolytic enhancing activity without the divalent copper cation. The present invention also relates to compositions, methods for degrading or converting a cellulosic material, and methods for producing a fermentation product.

Abstract translation: 本发明涉及增加具有纤维素分解增强活性的GH61多肽的活性的方法，包括：向包含具有纤维素分解增强活性的GH61多肽的组合物中加入二价铜阳离子，其中二价铜阳离子和GH61多肽的存在 与不含二价铜阳离子的具有纤维素分解增强活性的GH61多肽相比，具有纤维素分解增强活性增加了酶组合物的纤维素材料的降解或转化。 本发明还涉及组合物，降解或转化纤维素材料的方法，以及用于生产发酵产物的方法。