公开(公告)号：US20190085309A1

公开(公告)日：2019-03-21

申请号：US16081168

申请日：2017-03-02

Applicant: Novozymes A/S

Inventor： Mark Wogulis ,  Leslie Demars ,  Aubrey Jones ,  Hanshu Ding ,  David Osborn

IPC: C12N9/42 ,  C12N15/52 ,  C12N15/82 ,  C12P19/14 ,  C07K14/42

CPC classification number: C12N9/2437 ,  C07K14/42 ,  C12N15/52 ,  C12N15/8241 ,  C12N2015/8518 ,  C12P19/14 ,  C12Y302/01004

Abstract: The present invention relates to cellobiohydrolase variants, polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of producing and using the variants.

公开(公告)号：US20220025348A1

公开(公告)日：2022-01-27

申请号：US17311738

申请日：2019-12-10

Applicant: NOVOZYMES A/S

Inventor： Nikolaj Spodsberg ,  David Osborn

IPC: C12N9/24 ,  C12P19/02

Abstract: The present invention relates to isolated polypeptides having xylanase activity, catalytic domains, carbohydrate binding modules and polynucleotides encoding the polypeptides, catalytic domains or carbohydrate binding modules. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains or carbohydrate binding modules.

公开(公告)号：US20200325463A1

公开(公告)日：2020-10-15

申请号：US16917505

申请日：2020-06-30

Applicant: Novozymes A/S

Inventor： Mark Wogulis ,  Leslie Demars ,  Aubrey Jones ,  Hanshu Ding ,  David Osborn

IPC: C12N9/42 ,  C07K14/42 ,  C12N15/52 ,  C12N15/82 ,  C12P19/14

Abstract: The present invention relates to cellobiohydrolase variants, polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of producing and using the variants.

公开(公告)号：US10738293B2

公开(公告)日：2020-08-11

申请号：US16081168

申请日：2017-03-02

Applicant: Novozymes A/S

Inventor： Mark Wogulis ,  Leslie Demars ,  Aubrey Jones ,  Hanshu Ding ,  David Osborn

IPC: C12N9/42 ,  C12P19/14 ,  C12N15/85 ,  C07K14/42 ,  C12N15/52 ,  C12N15/82

Abstract: The present invention relates to cellobiohydrolase variants, polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of producing and using the variants.

公开(公告)号：US20180051306A1

公开(公告)日：2018-02-22

申请号：US15557305

申请日：2016-03-11

Applicant: Novozymes A/S ,  Beta Renewables Spa

Inventor： Jesper Frickmann ,  Johan Belfrage ,  Eric Abbate ,  David Osborn ,  Geoffrey Moxley ,  Daniele Riva ,  Piero Otonello ,  Simone Ferrero ,  Micol Purrotti ,  Stefano Paravisi ,  Chiara Prefumo

IPC: C12P19/14 ,  C12P19/02

CPC classification number: C12P19/14 ,  C12P7/10 ,  C12P19/02 ,  C12P2203/00 ,  C12Y302/01 ,  C12Y302/01008 ,  C12Y302/01021 ,  C12Y302/01037 ,  C12Y302/01091 ,  Y02E50/16

Abstract: The invention relates to processes of closing an observed gap in sugar yield between pure batch hydrolysis and a multi-stage hydrolysis containing a continuous reactor. Enzyme compositions containing varied ratios of cellulolytic composition and a hemicellulolytic composition preconditioning are used in multi-stage hydrolysis processes containing a continuous reactor in order to close the gap. Such enzyme compositions are useful in multi-stage saccharification of a lignocellulosic material, fermentation processes following multi-stage saccharification of a lignocellulosic material and in improving a glucose or xylose yield in multi-stage saccharification of a lignocellulosic material.

公开(公告)号：US11965189B2

公开(公告)日：2024-04-23

申请号：US16088038

申请日：2017-03-24

Applicant: Novozymes A/S

Inventor： Mark Wogulis ,  Leslie DeMars ,  David Osborn

IPC: C12N9/42 ,  C12P7/10 ,  C12P19/02 ,  C12P19/14

CPC classification number: C12N9/2437 ,  C12P7/10 ,  C12P19/02 ,  C12P19/14 ,  C12Y302/01

Abstract: The present invention relates to cellobiohydrolase variants having increased thermal activity or thermostability, polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

公开(公告)号：US11053489B2

公开(公告)日：2021-07-06

申请号：US16917505

申请日：2020-06-30

Applicant: Novozymes A/S

Inventor： Mark Wogulis ,  Leslie Demars ,  Aubrey Jones ,  Hanshu Ding ,  David Osborn

IPC: C12N15/52 ,  C12N9/42 ,  C12N15/82 ,  C12N1/14 ,  C12N1/20 ,  C07K14/42 ,  C12P19/14 ,  C12N15/85

Abstract: The present invention relates to cellobiohydrolase variants, polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of producing and using the variants.

公开(公告)号：US20200299664A1

公开(公告)日：2020-09-24

申请号：US16088038

申请日：2017-03-24

Applicant: Novozymes A/S

Inventor： Mark Wogulis ,  Leslie DeMars ,  David Osborn

IPC: C12N9/42 ,  C12P19/14 ,  C12P19/02 ,  C12P7/10

Abstract: The present invention relates to cellobiohydrolase variants having increased thermal activity or thermostability, polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

公开(公告)号：US20180044707A1

公开(公告)日：2018-02-15

申请号：US15557300

申请日：2016-03-11

Applicant: Novozymes A/S ,  Beta Renewables Spa

Inventor： Jesper Frickmann ,  Johan Belfrage ,  Eric Abbate ,  David Osborn ,  Geoffrey Moxley ,  Daniele Riva ,  Piero Otonello ,  Simone Ferrero ,  Micol Purrotti ,  Stefano Paravisi ,  Chiara Prefumo

IPC: C12P19/14 ,  C12P19/02

CPC classification number: C12P19/14 ,  C12P7/06 ,  C12P19/02 ,  C12P2201/00 ,  C12Y302/01 ,  C12Y302/01008 ,  C12Y302/01037 ,  Y02E50/17

Abstract: The invention relates to processes of multi-stage hydrolysis where different enzyme compositions are added in at least two stages of hydrolysis. In a first stage, a first enzyme composition of xylanase, a beta-xylosidase and an endoglucanase is added, followed by a latter stage in which a second enzyme composition, a cellulolytic enzyme composition, is added. Also provided are processes for obtaining hydrolysis products and fermentation products using processes of the invention.

公开(公告)号：US20170369860A1

公开(公告)日：2017-12-28

申请号：US15538816

申请日：2016-01-06

Applicant: Novozymes A/S

Inventor： Robert Blazej ,  Charles Emrich ,  Nicholas Toriello ,  Hanshu Ding ,  David Osborn ,  Aubrey Jones

IPC: C12N9/42 ,  C12P19/14 ,  C12P5/02 ,  C12P5/00 ,  D21C5/00 ,  C12P7/40 ,  C12P3/00

CPC classification number: C12N9/2437 ,  C12P3/00 ,  C12P5/007 ,  C12P5/02 ,  C12P5/023 ,  C12P5/026 ,  C12P7/04 ,  C12P7/40 ,  C12P19/14 ,  C12Y302/01004 ,  D21C5/005 ,  D21H17/005 ,  Y02E50/343

Abstract: The present invention relates to endoglucanase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, expression vectors, and recombinant host cells comprising the polynucleotides; and methods of using the variants.