Bacterial Mutants with Improved Transformation Efficiency
    10.
    发明申请
    Bacterial Mutants with Improved Transformation Efficiency 有权
    具有改善转化效率的细菌突变体

    公开(公告)号:US20150125959A1

    公开(公告)日:2015-05-07

    申请号:US14397512

    申请日:2013-05-17

    申请人: Novozymes A/S

    IPC分类号: C12N15/74

    摘要: Provided herein are Lactobacillus mutants having improved transformation efficiency, comprising a disruption to an endogenous gene encoding a restriction modification system protein. Also described are methods for producing the mutants, methods for generating transformants using the mutants, and methods for producing a polypeptide or fermentation product using the mutants.

    摘要翻译: 本文提供了具有改善的转化效率的乳杆菌突变体,其包含对编码限制性修饰系统蛋白质的内源基因的破坏。 还描述了用于产生突变体的方法,使用突变体产生转化体的方法,以及使用突变体产生多肽或发酵产物的方法。