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公开(公告)号:US11573171B2
公开(公告)日:2023-02-07
申请号:US16821538
申请日:2020-03-17
Applicant: OLYMPUS CORPORATION
Inventor: Ikutoshi Fukushima , Shogo Usui , Tsuyoshi Mochizuki , Masaru Mizunaka , Shintaro Takahashi
IPC: H04N7/18 , G01N21/27 , G06T7/90 , H04N9/04 , C12M1/00 , C12M1/34 , G01N21/25 , G02B21/06 , G02B21/36 , G06T7/00 , H04N5/225
Abstract: An observation system includes an observation apparatus including a housing having an arrangement surface for placement of a sample, the sample including a culture medium, and an external illumination unit which is disposed outside the housing and includes at least one light source configured to emit illumination light. At least a part of the arrangement surface is formed of a transparent member having an optically transparent property. The observation apparatus includes an imaging unit which is provided in the housing and includes an image sensor configured to image, via the transparent member, the sample illuminated by the illumination light from the external illumination unit to acquire images of at least three colors.
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2.
公开(公告)号:US09354442B2
公开(公告)日:2016-05-31
申请号:US13939286
申请日:2013-07-11
Applicant: OLYMPUS CORPORATION
Inventor: Shintaro Takahashi
CPC classification number: G02B26/105 , G01B11/24
Abstract: A scanning rate is increased without causing the light utilization efficiency to decrease. An optical scanning device includes a polarization switching unit that switches the polarization direction of a beam at a predetermined switching timing; at least one polarization beam splitter that splits the beam into two optical paths in accordance with the polarization direction switched by the polarization switching unit; a reflecting optical system that causes the beams split by the polarization beam splitter to have relative angles in the same plane so as to make the beams meet at the same location; and a scanner that scans the beams made to meet at the same location by means of the reflecting optical system in a direction parallel to the plane in synchronization with the switching timing of the polarization switching unit.
Abstract translation: 增加扫描速率,而不会降低光利用效率。 光学扫描装置包括在预定的切换定时切换光束的偏振方向的偏振切换单元; 至少一个偏振分束器,其根据由偏振切换单元切换的偏振方向将光束分成两个光路; 反射光学系统,其使得由偏振分束器分束的光束在相同平面中具有相对角度,以使得光束在相同位置处相遇; 以及扫描器,其与所述偏振切换单元的切换定时同步地扫描通过所述反射光学系统在与所述平面平行的方向上在相同位置处相交的光束。
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公开(公告)号:US11037293B2
公开(公告)日:2021-06-15
申请号:US16458397
申请日:2019-07-01
Applicant: OLYMPUS CORPORATION
Inventor: Naohiro Ariga , Shintaro Takahashi , Yohei Tanikawa , Shinichi Takimoto
IPC: G06T7/00 , G01N33/483 , G06F17/18
Abstract: A cell observation system includes an imaging element that acquires images of the inside of a culture container in which cells are cultured, the imaging element acquiring the images over time; a computer configured to: quantitatively analyze a culture state of the cells cultured in the culture container on the basis of each of the images acquired by the imaging element; and statistically analyze the quantitatively analyzed data; and a display that displays statistical analysis results in the culture container within a plurality of subculture periods obtained by the computer in a manner allowing comparison of the statistical analysis results.
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公开(公告)号:US10914931B2
公开(公告)日:2021-02-09
申请号:US16003402
申请日:2018-06-08
Applicant: OLYMPUS CORPORATION
Inventor: Tadashi Hirata , Shintaro Takahashi
Abstract: An observation device including: a stage having a transparent pedestal surface; an illumination system under the pedestal surface, the illumination system emitting illumination light toward the pedestal surface; and an object system under the pedestal surface for capturing transmission light generated from the illumination light, reflected off a reflection surface and transmitted through a sample. Wherein a first light path in the illumination system is different from a second light path in the object system, in a first pupil surface of the illumination system, the illumination system generates the illumination light by restricting light in a first transparent region, in a second pupil surface of the object system, the object system restricts the transmission light in a second transparent region, and the second transparent region has first and second subregions with different transmittance, the second subregion located between the first subregion and an edge of the second transparent region.
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公开(公告)号:US20200318058A1
公开(公告)日:2020-10-08
申请号:US16904799
申请日:2020-06-18
Applicant: OLYMPUS CORPORATION
Inventor: Tsuyoshi Mochizuki , Koh Mohri , Yoshihito Iguchi , Shogo Usui , Shintaro Takahashi , Asuka Nakamura , Shoichi Kaneko , Ikutoshi Fukushima , Masaru Mizunaka
Abstract: An observation system includes an illumination unit including a light source from which emits an illumination light including light of a plurality of colors, and light receiving unit including an optical sensor which acquires a light intensity. The illumination unit emits the illumination light for a culture vessel so that the illumination light travels from a first side to a second side of the culture vessel, the first side and the second side being defined by interposing a culture medium. The light receiving unit receives, on the first side, light emitted from the illumination unit, entering the culture vessel from the first side, reflected at the second side, and transmitted through the culture medium, and acquires a light intensity for each color in the received light for calculation of a pH value of the culture medium.
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公开(公告)号:US20200217782A1
公开(公告)日:2020-07-09
申请号:US16821538
申请日:2020-03-17
Applicant: OLYMPUS CORPORATION
Inventor: Ikutoshi Fukushima , Shogo Usui , Tsuyoshi Mochizuki , Masaru Mizunaka , Shintaro Takahashi
IPC: G01N21/27 , H04N5/225 , H04N9/04 , G06T7/90 , G06T7/00 , C12M1/00 , C12M1/34 , G02B21/36 , G02B21/06 , G01N21/25
Abstract: An observation system includes an observation apparatus including a housing having an arrangement surface for placement of a sample, the sample including a culture medium, and an external illumination unit which is disposed outside the housing and includes at least one light source configured to emit illumination light. At least a part of the arrangement surface is formed of a transparent member having an optically transparent property. The observation apparatus includes an imaging unit which is provided in the housing and includes an image sensor configured to image, via the transparent member, the sample illuminated by the illumination light from the external illumination unit to acquire images of at least three colors.
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公开(公告)号:US10352861B2
公开(公告)日:2019-07-16
申请号:US16215809
申请日:2018-12-11
Applicant: OLYMPUS CORPORATION
Inventor: Asuka Suekane , Shintaro Takahashi , Kentaro Imoto , Atsushi Doi , Shinichi Takimoto
IPC: G01N21/64
Abstract: An observation assistance device of the present invention includes: an information storage unit that stores sample state information showing a sample state change, a type of sample, a type of fluorescent substance, and an observation condition in fluorescence observation performed on a predetermined sample, and under a predetermined observation condition; an input unit via which inputs the type of sample to be observed and the type of fluorescent substance to be used; an assistance-display generating unit that reads sample state information and an observation condition of fluorescence observation performed on the same type of sample as the type of sample input, using the same type of fluorescent substance as the type of fluorescent substance, and generates an assistance display showing the sample state information in relation to the two or more parameters included in the observation condition; and a display unit that displays the generated assistance display.
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8.
公开(公告)号:US09268133B2
公开(公告)日:2016-02-23
申请号:US14279950
申请日:2014-05-16
Applicant: OLYMPUS CORPORATION
Inventor: Shintaro Takahashi
CPC classification number: G02B26/105 , G02B21/002 , G02B26/101
Abstract: Provided is an optical scanning apparatus including: a deflector capable of deflecting an entering beam while switching an advancing direction thereof among a plurality of direction at a predetermined switching timing; a mirror array including a plurality of angle setting mirrors that are placed at angles different from one another on respective optical paths of the beams deflected by the deflector, each of the angle setting mirrors reflecting the beam while giving thereto a relative angle on the same plane for each optical path, and gathering the beam on the same point; and a first scanner that is provided so as to be swingable about an axial line perpendicular to the plane in synchronization with the switching timing, the first scanner reflecting each beam that is caused by the mirror array to enter the same point from a different direction and applying for scanning the beam along the same trajectory.
Abstract translation: 提供一种光学扫描装置,包括:偏转器,其能够在预定的切换定时在多个方向上切换进入光束同时切换进入光束; 包括多个角度设定镜的反射镜阵列,所述多个角度设定镜在由偏转器偏转的光束的各个光路上以彼此不同的角度放置,每个角度设定镜反射光束,同时在同一平面上给出相对角度 对于每个光路,并将光束聚集在同一点上; 以及第一扫描仪,其被设置为能够与切换定时同步地围绕垂直于该平面的轴线摆动,第一扫描器反射由反射镜阵列引起的每个光束从不同方向进入相同点,并且 沿同一轨迹应用扫描光束。
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公开(公告)号:US11226476B2
公开(公告)日:2022-01-18
申请号:US16366682
申请日:2019-03-27
Applicant: OLYMPUS CORPORATION
Inventor: Tsuyoshi Mochizuki , Shintaro Takahashi , Akira Matsushita , Yohei Tanikawa , Masaru Mizunaka , Shinichi Takimoto
IPC: G02B21/34 , G02B21/08 , G02B21/26 , G02B21/36 , G01N21/59 , G01N21/01 , G02B21/33 , G01N21/17 , C12M1/34
Abstract: An observation apparatus including: a top plate on which a container in which a specimen is accommodated can be placed, and through which illumination light can pass; a light source that emits the illumination light upward from below the specimen; an objective lens that focuses, below the specimen and the top plate, transmitted light which is the illumination light that has passed through the specimen from thereabove and that has passed through the top plate; and a camera that captures the transmitted light, wherein the light source emits the illumination light toward an area above the specimen from outside the objective lens in a radial direction, and the top plate is provided with a mark that specifies a viewing-field area of the camera.
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公开(公告)号:US11137588B2
公开(公告)日:2021-10-05
申请号:US16364946
申请日:2019-03-26
Applicant: OLYMPUS CORPORATION
Inventor: Masaru Mizunaka , Shintaro Takahashi , Akira Matsushita , Yohei Tanikawa , Tsuyoshi Mochizuki , Shinichi Takimoto
IPC: G02B21/06 , G02B21/16 , G02B21/02 , G02B21/12 , G01N21/64 , G02B21/36 , G02B21/10 , G01N21/17 , G02B21/24 , G02B21/33
Abstract: An observation apparatus including: a light-source that emits illumination light and excitation light upward from below a specimen; and an image-capturing optical system having an objective lens that focuses, below the specimen, transmitted light, which is the illumination light that is emitted from the light-source, that is reflected above the specimen, and that has passed through the specimen, and fluorescence that is generated in the specimen that has been irradiated with the excitation light emitted from the light-source, wherein the light-source is disposed radially outside the objective lens.
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