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公开(公告)号：US11573171B2
公开(公告)日：2023-02-07
申请号：US16821538
申请日：2020-03-17
申请人： OLYMPUS CORPORATION
IPC分类号： H04N7/18 , G01N21/27 , G06T7/90 , H04N9/04 , C12M1/00 , C12M1/34 , G01N21/25 , G02B21/06 , G02B21/36 , G06T7/00 , H04N5/225
摘要： An observation system includes an observation apparatus including a housing having an arrangement surface for placement of a sample, the sample including a culture medium, and an external illumination unit which is disposed outside the housing and includes at least one light source configured to emit illumination light. At least a part of the arrangement surface is formed of a transparent member having an optically transparent property. The observation apparatus includes an imaging unit which is provided in the housing and includes an image sensor configured to image, via the transparent member, the sample illuminated by the illumination light from the external illumination unit to acquire images of at least three colors.
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公开(公告)号：US20200318058A1
公开(公告)日：2020-10-08
申请号：US16904799
申请日：2020-06-18
申请人： OLYMPUS CORPORATION
发明人： Tsuyoshi Mochizuki , Koh Mohri , Yoshihito Iguchi , Shogo Usui , Shintaro Takahashi , Asuka Nakamura , Shoichi Kaneko , Ikutoshi Fukushima , Masaru Mizunaka
摘要： An observation system includes an illumination unit including a light source from which emits an illumination light including light of a plurality of colors, and light receiving unit including an optical sensor which acquires a light intensity. The illumination unit emits the illumination light for a culture vessel so that the illumination light travels from a first side to a second side of the culture vessel, the first side and the second side being defined by interposing a culture medium. The light receiving unit receives, on the first side, light emitted from the illumination unit, entering the culture vessel from the first side, reflected at the second side, and transmitted through the culture medium, and acquires a light intensity for each color in the received light for calculation of a pH value of the culture medium.
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公开(公告)号：US20200217782A1
公开(公告)日：2020-07-09
申请号：US16821538
申请日：2020-03-17
申请人： OLYMPUS CORPORATION
IPC分类号： G01N21/27 , H04N5/225 , H04N9/04 , G06T7/90 , G06T7/00 , C12M1/00 , C12M1/34 , G02B21/36 , G02B21/06 , G01N21/25
摘要： An observation system includes an observation apparatus including a housing having an arrangement surface for placement of a sample, the sample including a culture medium, and an external illumination unit which is disposed outside the housing and includes at least one light source configured to emit illumination light. At least a part of the arrangement surface is formed of a transparent member having an optically transparent property. The observation apparatus includes an imaging unit which is provided in the housing and includes an image sensor configured to image, via the transparent member, the sample illuminated by the illumination light from the external illumination unit to acquire images of at least three colors.
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公开(公告)号：US10317658B2
公开(公告)日：2019-06-11
申请号：US14789293
申请日：2015-07-01
申请人： OLYMPUS CORPORATION
摘要： A microscope includes: an objective lens having an optical system; a correction collar provided on the objective lens and configured to move the optical system in a direction of an optical axis of the optical system by rotating around the objective lens to correct aberration; a switching unit to which the objective lens is attachable and which switches a position of the objective lens; a supporting unit for supporting the switching unit; and a focusing unit that holds the supporting unit such that the supporting unit is movable along the optical axis of the objective lens. A correction collar operating device is detachably attached to the supporting unit and includes: an input unit for inputting rotary force to rotate the correction collar; and a correction collar driving unit for rotating the correction collar according to the rotary force while the correction collar driving unit has contact with the correction collar.
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公开(公告)号：US20180179487A1
公开(公告)日：2018-06-28
申请号：US15848623
申请日：2017-12-20
申请人： OLYMPUS CORPORATION
发明人： Akira MATSUSHITA , Shintaro Takahashi , Masaru Mizunaka , Shinichi Takimoto , Tadashi Hirata , Yohei Tanikawa
CPC分类号： C12M41/46 , G01J5/0003 , G01J5/04 , G01J5/061 , G01J5/0896 , G01J5/10 , G01J2005/0077 , G01J2005/068 , H04N5/2252 , H04N5/2256 , H04N5/33
摘要： Provided is an observation apparatus including: a housing that has, in a top face thereof, a transmission window on which a container accommodating cells can be placed and through which light can pass; a camera portion that is accommodated in the housing and that captures observation light coming from the cells irradiated with illumination light emitted from an illumination portion and entering the housing by passing through a bottom face of the container and the transmission window of the housing; and a housing-interior heating portion that is accommodated in the housing and that heats the cells.
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公开(公告)号：US11443415B2
公开(公告)日：2022-09-13
申请号：US17142703
申请日：2021-01-06
申请人： OLYMPUS CORPORATION
发明人： Masaru Mizunaka
摘要： An inspection method for inspecting a counting function of an imaging system that captures an image of a phase object includes: capturing an image of a reference standard plate that includes a base region and a plurality of counting target regions having a phase amount in a thickness direction different from a phase amount of the base region, under a condition where the number of counting target regions positioned within a field of view of the imaging system is specified among the plurality of counting target regions; counting the counting target regions included in the captured image of the reference standard plate; and outputting at least a counted result of the counting target regions.
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公开(公告)号：US11226476B2
公开(公告)日：2022-01-18
申请号：US16366682
申请日：2019-03-27
申请人： OLYMPUS CORPORATION
发明人： Tsuyoshi Mochizuki , Shintaro Takahashi , Akira Matsushita , Yohei Tanikawa , Masaru Mizunaka , Shinichi Takimoto
IPC分类号： G02B21/34 , G02B21/08 , G02B21/26 , G02B21/36 , G01N21/59 , G01N21/01 , G02B21/33 , G01N21/17 , C12M1/34
摘要： An observation apparatus including: a top plate on which a container in which a specimen is accommodated can be placed, and through which illumination light can pass; a light source that emits the illumination light upward from below the specimen; an objective lens that focuses, below the specimen and the top plate, transmitted light which is the illumination light that has passed through the specimen from thereabove and that has passed through the top plate; and a camera that captures the transmitted light, wherein the light source emits the illumination light toward an area above the specimen from outside the objective lens in a radial direction, and the top plate is provided with a mark that specifies a viewing-field area of the camera.
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公开(公告)号：US11137588B2
公开(公告)日：2021-10-05
申请号：US16364946
申请日：2019-03-26
申请人： OLYMPUS CORPORATION
发明人： Masaru Mizunaka , Shintaro Takahashi , Akira Matsushita , Yohei Tanikawa , Tsuyoshi Mochizuki , Shinichi Takimoto
IPC分类号： G02B21/06 , G02B21/16 , G02B21/02 , G02B21/12 , G01N21/64 , G02B21/36 , G02B21/10 , G01N21/17 , G02B21/24 , G02B21/33
摘要： An observation apparatus including: a light-source that emits illumination light and excitation light upward from below a specimen; and an image-capturing optical system having an objective lens that focuses, below the specimen, transmitted light, which is the illumination light that is emitted from the light-source, that is reflected above the specimen, and that has passed through the specimen, and fluorescence that is generated in the specimen that has been irradiated with the excitation light emitted from the light-source, wherein the light-source is disposed radially outside the objective lens.
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