公开(公告)号：US20170160148A1

公开(公告)日：2017-06-08

申请号：US15437985

申请日：2017-02-21

Applicant: Osaka City University

Inventor： Souichi SAEKI

IPC: G01L1/24 ,  G01N21/21 ,  G01B9/02

CPC classification number: G01L1/24 ,  G01B9/02091 ,  G01B11/168 ,  G01L1/241 ,  G01N21/21

Abstract: A control computation unit causes an optical modulator to change a polarization state to shift a phase of polarized light with which an object is irradiated, computes a spatial gradient of tomographic distribution of phase difference of an interference signal on the basis of phase differences of interference signals each obtained by each phase shift of the polarized light, and visually displays tomographic distribution of spatial gradient in association with tomographic distribution of stress on the display device. The control computation unit computes deformation rate vector distribution at cross-sectional positions of the object on the basis of optical interference signals, and further computes tomographic distribution of strain rate tensor. The control computation unit then computes tomographic distribution of mechanical property value from the tomographic distribution of stress and the tomographic distribution of strain rate tensor, and visually displays the tomographic distribution of mechanical property value.

公开(公告)号：US20190125247A1

公开(公告)日：2019-05-02

申请号：US16224261

申请日：2018-12-18

Applicant: OSAKA CITY UNIVERSITY ,  SHISEIDO COMPANY, LTD.

Inventor： Souichi SAEKI ,  Yusuke HARA ,  Toyonobu YAMASHITA

IPC: A61B5/00 ,  A61B5/026

Abstract: A skin diagnosing device includes an optical unit including: an optical system that uses OCT; an optical mechanism to guide light from the optical unit to skin to scan the skin; a loading device to apply predetermined deformation energy to the skin; a control computation unit to compute tomographic distribution of predetermined status values relating to the skin by controlling driving of the loading device and the optical mechanism and processing optical interference signals output from the optical unit in response to the driving, to compute an evaluation value of the skin based on the tomographic distribution; and a display device to display the evaluation value of the skin. The control computation unit computes the evaluation value by computing mechanical characteristics and a blood flow condition of the skin as the status values and associating the mechanical characteristics and the blood flow condition at a cross-sectional position of the skin.

公开(公告)号：US20180206741A1

公开(公告)日：2018-07-26

申请号：US15743210

申请日：2016-07-11

Applicant: OSAKA CITY UNIVERSITY

Inventor： Souichi SAEKI ,  Masatsugu SHIBA

IPC: A61B5/026 ,  A61B5/00

CPC classification number: A61B5/0261 ,  A61B1/018 ,  A61B1/2736 ,  A61B5/0066 ,  A61B5/0073 ,  A61B5/4238 ,  A61B5/6847 ,  A61B5/6852

Abstract: A cancer invasiveness diagnosis system includes an endoscope; a microtomography probe which is introduced into a body cavity together with the endoscope, the microtomography probe emitting a low-coherence light on a target tissue in which a target tumor is present to obtain an optical interference signal; a determination portion which is configured to obtain a tomography image of the target tissue including the target tumor and a blood flow velocity information in a blood vessel in the tomography image based on the optical interference signal, wherein the determination portion is configured to determine the cancer invasiveness of the target tumor based on the tomography image and the blood flow velocity information.