公开(公告)号：US11951229B2

公开(公告)日：2024-04-09

申请号：US17407982

申请日：2021-08-20

Applicant: AOBAKASEI KABUSHIKI KAISHA ,  OSAKA CITY UNIVERSITY IN UNIVERSITY PUBLIC CORPORATION OSAKA

Inventor： Hirotsugu Kido ,  Katsunori Chiba ,  Hironori Arima ,  Kenji Ohata

IPC: A61L26/00

CPC classification number: A61L26/0038 ,  A61L26/0004 ,  A61L26/0023 ,  A61L26/0047 ,  A61L2400/04

Abstract: To provide a liquid medical material maintaining a colloid in a more sol form than a solid at normal temperature, having a higher function as a wound dressing material and a hemostatic material than fibrin glue, and being able to be produced safely and inexpensively. A gelatin aqueous solution including calcium at a concentration of 0.2 M or more and 1.0 M or less, and having a concentration of 5% by weight or more and 40% by weight or less, an average molecular weight of 80,000 or more and 120,000 or less, and a molecular weight distribution of 20,000 or more and 300,000 or less, and transglutaminase inducing crosslinking of the gelatin, are included. It is preferable that the calcium has a concentration of 0.2 M or more and 0.7 M or less, the gelatin has a bloom of 160 or more and 250 or less, and the transglutaminase has activity per unit of 36 U/ml to 400 U/ml.

公开(公告)号：US20220082854A1

公开(公告)日：2022-03-17

申请号：US17456316

申请日：2021-11-23

Applicant: OSAKA CITY UNIVERSITY ,  KYOCERA Corporation

Inventor： Hideya TAKAHASHI ,  Goro Hamagishi ,  Kaoru Kusafuka

IPC: G02B30/28 ,  H04N13/305 ,  G02B27/01 ,  G02B30/27 ,  G02B30/29 ,  G02B30/31 ,  G02B30/32

Abstract: A three-dimensional display apparatus comprises a display panel (display element) and a parallax barrier (optical element). The display panel displays a left-eye image and a right-eye image respectively in first subpixels and second subpixels. The parallax barrier transmits at least part of the left-eye image toward the left eye, and at least part of the right-eye image toward the right eye. A first certain number of the first subpixels and of the second subpixels are each successively arranged in each column. A region in which the first subpixels are arranged and a region in which the second subpixels are arranged are displaced from each other by a second certain number between two adjacent columns. The first certain number is greater than the second certain number and is not a multiple of the second certain number.

公开(公告)号：US11215820B2

公开(公告)日：2022-01-04

申请号：US16481406

申请日：2018-01-26

Applicant: OSAKA CITY UNIVERSITY ,  KYOCERA Corporation

Inventor： Hideya Takahashi ,  Goro Hamagishi ,  Kaoru Kusafuka

IPC: G03H1/00 ,  G02B27/01 ,  H04N13/305 ,  G02B30/27

Abstract: A three-dimensional display apparatus comprises a display panel (display element) and a parallax barrier (optical element). The display panel displays a left-eye image and a right-eye image respectively in first subpixels and second subpixels. The parallax barrier transmits at least part of the left-eye image toward the left eye, and at least part of the right-eye image toward the right eye. A first certain number of the first subpixels and of the second subpixels are each successively arranged in each column. A region in which the first subpixels are arranged and a region in which the second subpixels are arranged are displaced from each other by a second certain number between two adjacent columns. The first certain number is greater than the second certain number and is not a multiple of the second certain number.

公开(公告)号：US20200148753A1

公开(公告)日：2020-05-14

申请号：US16436301

申请日：2019-06-10

Applicant: OSAKA CITY UNIVERSITY ,  TEIJIN PHARMA LIMITED

Inventor： Hiroshi Mori ,  Takami Tomiyama ,  Yoichi Matsumoto ,  Hiroshi Eguchi ,  Yuichi Kunori

IPC: C07K16/18 ,  C07K14/47

Abstract: [PURPOSE]The invention provides a novel therapeutic agent or prophylactic agent for cognitive disorders.[SOLUTION MEANS]The invention provides an antibody that participates in antigen-antibody reaction specifically with tau protein that has been phosphorylated in the vicinity of Ser413 of SEQ ID NO: 1, and a therapeutic agent or prophylactic agent for cognitive disorders comprising as an active ingredient a peptide that has been phosphorylated in the vicinity of Ser413.

公开(公告)号：US20190269393A1

公开(公告)日：2019-09-05

申请号：US16319908

申请日：2017-07-21

Applicant: OSAKA CITY UNIVERSITY ,  OZK CO., LTD. ,  SHINWA SYOJI CO., LTD.

Inventor： Toshihiko SHIBATA ,  Haruhiko YAMASAKI ,  Katsunori MITSUHASHI ,  Yoshiro MORISHITA

IPC: A61B17/02

Abstract: This retractor easily ensures a surgical field as desired by an operator, can flexibly ensure and change the surgical field in accordance with the surgical site and the surgical situation, and can easily be moved to a desired position in the surgical site and taken out after the surgery. A retractor 1 holds a surgical incision in a body in an opened state to ensure a surgical field in small-incision endoscopic surgery, and includes a base body 2 that is a thin plate made of tin having a purity of not less than 99.9% and has an elongated rectangular shape in an extended state of the base body. The retractor 1, in an extended form in a rectangular shape or in a rounded form in a small shape, can be inserted from a small incision wound into the body, and can easily be delivered to the surgical incision in the body by a surgical instrument. The base body 2 is bent and deformed into a desired shape by the surgical instrument and is applied to the surgical incision in the body, so that the surgical incision can be held in an opened state so as to ensure the surgical field. The base body 2 is made of tin having a purity of not less than 99.9%, and thus the base body 2 has a high flexibility in particular, thereby allowing the base body 2 to be easily bent and deformed into a desired form by use of the surgical instrument.

公开(公告)号：US20190167173A1

公开(公告)日：2019-06-06

申请号：US16270794

申请日：2019-02-08

Applicant: OMRON HEALTHCARE Co., Ltd. ,  OSAKA CITY UNIVERSITY

Inventor： Kenji FUJII ,  Shingo YAMASHITA ,  Yasuyoshi WATANABE ,  Kei MIZUNO

IPC: A61B5/16 ,  A61B5/024 ,  A61B5/00

Abstract: A fatigue degree determination device includes a fatigue degree determination unit. A first biological heart rate is acquired while a user is awake and at rest, based on a biological heart rate measured from the user. A second biological heart rate is acquired while the user is sleeping, based on the biological heart rate measured from the user. The fatigue degree determination unit determines a fatigue degree of the user, based on information read out from a storage medium, the first biological heart rate and the second biological heart rate. The storage medium stores the information in which a degree of change of one biological heart rate relative to the other biological heart rate of a biological heart rate while a person is awake and at rest and a biological heart rate while the person is sleeping and a fatigue degree are associated with each other.

公开(公告)号：US09903900B2

公开(公告)日：2018-02-27

申请号：US14406690

申请日：2013-06-12

Applicant: OSAKA CITY UNIVERSITY

Inventor： Hiroaki Tsujimoto

IPC: G01R31/02 ,  G01R33/09 ,  G01R33/06 ,  G01R15/20 ,  H01H83/02 ,  H02H3/33

CPC classification number: G01R31/024 ,  G01R15/205 ,  G01R15/207 ,  G01R31/025 ,  G01R33/063 ,  G01R33/09 ,  H01H83/02 ,  H02H3/33

Abstract: There is a limit on the miniaturization of electric leakage detecting apparatuses including a ring-shaped magnetic material. Any thicker electric wires increase the size of the ring-shaped magnetic material. Additionally, it is difficult to place the ring-shaped magnetic material around the electric wires that have already been placed. In light of the foregoing, an electric leakage apparatus is provided. The electric leakage detecting apparatus is to be installed on a pair of power source lines connecting a power source and a load, and includes: a pair of holders configured to hold the power source lines, respectively; a fixing means configured to fix the holders at a predetermined interval; a pair of magnetic elements each placed on each of the holders while being parallel to the power source lines; a detecting means configured to detect a difference between magneto-resistance effects of the magnetic elements; and a driving means configured to feed a drive current to the magnetic elements.

公开(公告)号：US09689905B2

公开(公告)日：2017-06-27

申请号：US14388419

申请日：2013-03-19

Applicant: OSAKA CITY UNIVERSITY

Inventor： Hiroaki Tsujimoto

IPC: G01R33/02 ,  G01R21/08 ,  G01R21/00 ,  G01R33/07 ,  G01R1/00 ,  H01H1/00 ,  G01R1/20 ,  G01R15/14 ,  G01R15/20

CPC classification number: G01R21/08 ,  G01R1/00 ,  G01R1/203 ,  G01R15/142 ,  G01R15/205 ,  G01R21/00 ,  G01R33/072 ,  H01H1/00 ,  H01L2221/00

Abstract: A power measurement apparatus configured to measure power consumed at a load, the apparatus includes a magnetic film module, an adjuster, a measurement resistance, and a voltage detector. The magnetic film module is arranged so that a longitudinal direction of the magnetic film module is parallel to current flowing in the load. The adjuster is configured to adjust a pass-frequency and a phase of a voltage at one terminal of the magnetic film module. The measurement resistance is serial-connected to the magnetic film module. The voltage detector is configured to detect a voltage between both terminals of the magnetic film module.

公开(公告)号：US20160223595A1

公开(公告)日：2016-08-04

申请号：US15029318

申请日：2014-09-10

Applicant: OSAKA CITY UNIVERSITY

Inventor： Hiroaki TSUJIMOTO

IPC: G01R15/20 ,  G01R19/00

Abstract: An electric current measurement apparatus for measuring an electric current flowing in a conducting wire in a circuit to be measured, the electric current measurement apparatus characterized by having a magnetic element to which a drive electric current terminal and a measurement voltage terminal are provided, a holder for fixing a positional relationship of the conducting wire to a magnetic body, an electric current source capable of outputting at least one frequency of alternating electric current across the drive electric current terminal, a voltage meter for measuring a voltage across the measurement voltage terminal, and a low-pass filter provided between the measurement voltage terminal and the voltage meter.

Abstract translation: 一种用于测量被测电路中的导线中流动的电流的电流测量装置，其特征在于具有设置有驱动电流端子和测量电压端子的磁性元件的电流测量装置， 用于将导线的位置关系固定在磁体上，能够输出跨越驱动电流端子的交流电流的至少一个频率的电流源，用于测量测量电压端子两端的电压的电压计，以及 设置在测量电压端子和电压表之间的低通滤波器。

公开(公告)号：US20160222386A1

公开(公告)日：2016-08-04

申请号：US15135856

申请日：2016-04-22

Applicant: Osaka City University

Inventor： Akira Tachibana ,  Toshizumi Tanabe

IPC: C12N15/113

CPC classification number: C12N15/113 ,  A61K31/711 ,  C12N2310/113 ,  C12N2310/14 ,  C12N2310/3231 ,  C12N2310/3519 ,  C12N2310/50 ,  C12N2310/531 ,  C12N2310/533 ,  C12N2320/30

Abstract: The purpose of the present invention is to develop and provide a nucleic acid molecule that can specifically and efficiently inhibit the activity of a target RNAi molecule and can be produced safely at a low cost. Provided is a nucleic acid molecule for inhibiting the activity of a target RNAi molecule. The nucleic acid molecule comprises a single-stranded nucleic acid moiety that contains one unmodified DNA region composed of a nucleotide sequence completely or sufficiently complementary to a nucleotide sequence of a functional strand having the activity in the target RNAi molecule and a double-stranded nucleic acid moiety to be linked to at least one of the 5′-end and the 3′-end of the single-stranded nucleic acid moiety.