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公开(公告)号：US20090287066A1
公开(公告)日：2009-11-19
申请号：US12122856
申请日：2008-05-19
IPC分类号： A61B5/00
CPC分类号： A61B6/481 , A61B6/4441 , A61B6/504
摘要： A workflow for a minimally invasive intervention, such as a treatment for a cancerous tumor, includes positioning a patient at a multi-functional imaging apparatus, obtaining pre-interventional images of the anatomy of the patient using a computed tomography or angiography imaging function, performing the minimally invasive intervention while the patient is positioned at the multi-functional imaging apparatus and while using a fluoroscopic imaging function, and performing a post-interventional imaging of the patient's anatomy while the patient is positioned at the multi-functional imaging apparatus using the computed tomography or angiographic imaging function. If the post-interventional imaging determines that additional intervention is in order, the additional intervention is performed while the patient is positioned at the imaging apparatus. Pre-intervention images and data sets from other sources may be combined with or used during the intervention. A treatment planning step may be included following the pre-interventional imaging and the intervention.
摘要翻译： 用于微创干预的工作流程，例如用于癌性肿瘤的治疗，包括将患者定位在多功能成像装置上，使用计算机断层摄影或血管造影成像功能获得患者的解剖结构的介入前图像，执行 当患者位于多功能成像设备并且同时使用荧光透视成像功能时进行微创干预，并且当患者使用计算出的多功能成像设备定位在多功能成像设备时对患者的解剖结构进行介入后成像 断层扫描或血管造影成像功能。 如果介入后成像确定额外干预是有序的，则在患者定位在成像装置的同时执行附加介入。 来自其他来源的预干预图像和数据集可以在干预期间组合或使用。 治疗计划步骤可以包括在介入前成像和干预之后。
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2.发明申请Method and apparatus for generating a functional data set of a perfused region of the human or animal body 有权用于产生人或动物体的灌注区域的功能数据集的方法和装置公开(公告)号：US20100246916A1
公开(公告)日：2010-09-30
申请号：US12729269
申请日：2010-03-23
CPC分类号： A61B6/504 , A61B6/481 , A61B6/507 , A61B6/5235 , A61B2090/364
摘要： A method and apparatus for generating at least one functional data set of a perfused region of the human or animal body are proposed. A first image data set is supplied comprising at least two images of the perfused region recorded at different times before and after an injection of contrast agent into a first artery supplying the region. A second image data set is supplied comprising at least two images of the perfused region recorded at different times before and after an injection of contrast agent into a second artery supplying the region. A first functional data set is generated by pixel-based calculation of at least one perfusion parameter from the first image data set. A second functional data set is generated by pixel-based calculation of at least one perfusion parameter from the second image data set.
摘要翻译： 提出了一种用于产生人体或动物身体的灌注区域的至少一个功能数据集的方法和装置。 提供第一图像数据组，其包括在将造影剂注射到供应该区域的第一动脉之前和之后的不同时间记录的灌注区域的至少两个图像。 提供第二图像数据集，其包括在将造影剂注射到供应该区域的第二动脉之前和之后的不同时间记录的灌注区域的至少两个图像。 通过基于来自第一图像数据集的至少一个灌注参数的基于像素的计算来生成第一功能数据集。 通过基于来自第二图像数据集的至少一个灌注参数的基于像素的计算来生成第二功能数据集。
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3.发明授权Method and apparatus for generating a functional data set of a perfused region of the human or animal body 有权用于产生人或动物体的灌注区域的功能数据集的方法和装置公开(公告)号：US08755583B2
公开(公告)日：2014-06-17
申请号：US12729269
申请日：2010-03-23
CPC分类号： A61B6/504 , A61B6/481 , A61B6/507 , A61B6/5235 , A61B2090/364
摘要： A method and apparatus for generating at least one functional data set of a perfused region of the human or animal body are proposed. A first image data set is supplied comprising at least two images of the perfused region recorded at different times before and after an injection of contrast agent into a first artery supplying the region. A second image data set is supplied comprising at least two images of the perfused region recorded at different times before and after an injection of contrast agent into a second artery supplying the region. A first functional data set is generated by pixel-based calculation of at least one perfusion parameter from the first image data set. A second functional data set is generated by pixel-based calculation of at least one perfusion parameter from the second image data set.
摘要翻译： 提出了一种用于产生人体或动物身体的灌注区域的至少一个功能数据集的方法和装置。 提供第一图像数据组，其包括在将造影剂注射到供应该区域的第一动脉之前和之后的不同时间记录的灌注区域的至少两个图像。 提供第二图像数据集，其包括在将造影剂注射到供应该区域的第二动脉之前和之后的不同时间记录的灌注区域的至少两个图像。 通过基于来自第一图像数据集的至少一个灌注参数的基于像素的计算来生成第一功能数据集。 通过基于来自第二图像数据集的至少一个灌注参数的基于像素的计算来生成第二功能数据集。
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公开(公告)号：US20080247503A1
公开(公告)日：2008-10-09
申请号：US12061357
申请日：2008-04-02
IPC分类号： A61B6/03
CPC分类号： A61B6/504 , A61B6/032 , A61B6/4441 , A61B6/481 , A61B6/507
摘要： A system and method of obtaining perfusion data for cerebral tissue is described. The system includes a C-arm X-ray device and a computing system configured to obtain sets of rotational projection X-ray data suitable for reconstructing 3D voxel data sets. A first data set is obtained of the patient, and then contrast material is injected into the vascular system to obtain a second 1 data set. A first voxel data set is subtracted from the second voxel data set, and the resultant data set is processed so as to segment the contrast-enhanced vasculature from the remaining data. The segmented voxels are subtracted from the resultant voxel data set, so as to yield a functional data set representing the difference between the attenuation of the tissues after administering contrast agent and the tissues prior to administering the contrast agent, without the contrast enhanced vasculature. The attenuation of the functional data set represents the perfusion or cerebral blood volume (CBV).
摘要翻译： 描述了获得脑组织灌注数据的系统和方法。 该系统包括C臂X射线装置和被配置为获得适于重建3D体元数据集的旋转投影X射线数据的组的计算系统。 获得患者的第一数据集，然后将造影材料注入血管系统以获得第二个1数据集。 从第二体素数据集中减去第一体素数据集，并且处理结果数据集，以便从剩余数据中分割对比度增强的脉管系统。 从所得到的体元数据集中减去分割体素，从而产生表示施用造影剂之前的组织的衰减与施用造影剂之前的组织之间的差异的功能数据集，而没有对比度增强的脉管系统。 功能数据集的衰减表示灌注或脑血容量（CBV）。
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公开(公告)号：US08285014B2
公开(公告)日：2012-10-09
申请号：US12061357
申请日：2008-04-02
CPC分类号： A61B6/504 , A61B6/032 , A61B6/4441 , A61B6/481 , A61B6/507
摘要： A system and method of obtaining perfusion data for cerebral tissue is described. The system includes a C-arm X-ray device and a computing system configured to obtain sets of rotational projection X-ray data suitable for reconstructing 3D voxel data sets. A first data set is obtained of the patient, and then contrast material is injected into the vascular system to obtain a second 1 data set. A first voxel data set is subtracted from the second voxel data set, and the resultant data set is processed so as to segment the contrast-enhanced vasculature from the remaining data. The segmented voxels are subtracted from the resultant voxel data set, so as to yield a functional data set representing the difference between the attenuation of the tissues after administering contrast agent and the tissues prior to administering the contrast agent, without the contrast enhanced vasculature. The attenuation of the functional data set represents the perfusion or cerebral blood volume (CBV).
摘要翻译： 描述了获得脑组织灌注数据的系统和方法。 该系统包括C臂X射线装置和被配置为获得适于重建3D体元数据集的旋转投影X射线数据的组的计算系统。 获得患者的第一数据集，然后将造影材料注入血管系统以获得第二个1数据集。 从第二体素数据集中减去第一体素数据集，并且处理结果数据集，以便从剩余数据中分割对比度增强的脉管系统。 从所得到的体元数据集中减去分割体素，从而产生表示施用造影剂之前的组织的衰减与施用造影剂之前的组织之间的差异的功能数据集，而没有对比度增强的脉管系统。 功能数据集的衰减表示灌注或脑血容量（CBV）。
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6.发明授权Method for the three-dimensional representation of a structure influenced by a periodic process, and medical imaging system 有权用于周期性过程影响的结构的三维表示的方法，以及医学成像系统公开(公告)号：US07953267B2
公开(公告)日：2011-05-31
申请号：US11881379
申请日：2007-07-26
申请人： Michael Zellerhoff
发明人： Michael Zellerhoff
CPC分类号： G01N23/046 , A61B6/481 , A61B6/503 , A61B6/504 , A61B6/541 , G01N2223/419 , G01N2223/612
摘要： There is described a method for a periodic and three-dimensional representation of a periodically variable structure. A number of rotation images is generated for this purpose. The required rotations relating to the same event of the periodic process are started at intervals offset by a defined angle. From the rotation images, new image series are assembled with which three-dimensional representations relating to different phase ranges of the period are reconstructed.
摘要翻译： 描述了周期性和三维表示周期性变化结构的方法。 为此目的生成多个旋转图像。 与周期性过程的相同事件有关的所需旋转以间隔偏移定义的角度开始。 从旋转图像，组装新图像系列，重建与周期的不同相位范围有关的三维表示。
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公开(公告)号：US07734009B2
公开(公告)日：2010-06-08
申请号：US11284235
申请日：2005-11-21
申请人： Thomas Brunner , Klaus Klingenbeck-Regn , Michael Maschke , Alois Nöttling , Ernst-Peter Rührnschopf , Bernhard Scholz , Bernd Schreiber , Norbert Karl Strobel , Karl Wiesent , Michael Zellerhoff
发明人： Thomas Brunner , Klaus Klingenbeck-Regn , Michael Maschke , Alois Nöttling , Ernst-Peter Rührnschopf , Bernhard Scholz , Bernd Schreiber , Norbert Karl Strobel , Karl Wiesent , Michael Zellerhoff
IPC分类号： G01N23/083 , H05G1/02
CPC分类号： G06T11/005 , A61B6/466 , A61B6/504 , G06T2211/404
摘要： The invention relates to an angiographic x-ray diagnostic device for rotation angiography with an x-ray emitter which can be moved on a circular path about a patient located on a patient support table, with an image detector unit which can moved on the circular path facing the x-ray emitter, with a digital image system for recording a plurality of projection images by means of rotation angiography, with a device for image processing, by means of which the projection images are reconstructed into a 3D volume image, and with a device for correcting physical effects and/or inadequacies in the recording system such as truncation correction, scatter correction, ring artifact correction, correction of the beam hardening and/or of the low frequency drop for the soft tissue display of projection images and the 3D volume images resulting therefrom.
摘要翻译： 本发明涉及一种用X射线发射器进行旋转血管造影的血管造影X射线诊断装置，该X射线发射器可以围绕位于病人支撑台上的患者的圆形路径移动，图像检测器单元可在圆形路径上移动 面对x射线发射器，具有用于通过旋转血管造影记录多个投影图像的数字图像系统，具有用于图像处理的装置，通过该装置将投影图像重建成3D体积图像，并且利用 用于校正记录系统的物理效应和/或不足的装置，例如用于投影图像的软组织显示的截断校正，散射校正，环形伪影校正，光束硬化的校正和/或低频率下降以及3D体积 由此产生的图像。
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8.发明申请Method for the three-dimensional representation of a moving structure by a tomographic method 有权通过断层摄影法对移动结构进行三维表示的方法公开(公告)号：US20090092225A1
公开(公告)日：2009-04-09
申请号：US12221938
申请日：2008-08-07
申请人： Jan Boese , Wolfgang Harer , Michael Zellerhoff
发明人： Jan Boese , Wolfgang Harer , Michael Zellerhoff
CPC分类号： A61B6/025 , A61B6/027 , A61B6/4441 , A61B6/466 , A61B6/481 , A61B6/503 , A61B6/504 , A61B6/507 , G06T11/006 , G06T2211/404 , G06T2211/412 , G06T2211/436
摘要： The invention relates to a method for a three-dimensional representation of a moving structure by a tomographic method, in which during one recording pass a series of projection recordings is registered by an imaging unit at different recording angles between a start position and an end position, it being possible to reconstruct three-dimensional image data from the projection recordings with the following steps: a) generation of tomosynthesis projection recordings along a tomosynthesis scanning path; b) interpolation of the data of the tomosynthesis projection recordings in accordance with an interpolation algorithm in order to generate a projection data set; c) use of a tomosynthesis reconstruction method on the projection data set in order to generate a tomosynthesis volume image; d) repetition of steps b) and c) for all times of interest, and e) display of tomosynthesis representations from the tomosynthesis volume images.
摘要翻译： 本发明涉及一种用于通过断层摄影方法对运动结构进行三维表示的方法，其中在一次记录通过期间，成像单元以起始位置和结束位置之间的不同记录角度登记一系列投影记录 可以通过以下步骤从投影记录重建三维图像数据：a）沿着断层合成扫描路径生成断层合成投影记录; b）根据插值算法对所述断层合成投影记录的数据进行插值，以生成投影数据集; c）在投影数据集上使用断层合成重建方法，以便产生断层合成体积图像; d）对所有感兴趣的时间重复步骤b）和c），以及e）从断层合成体积图像显示断层合成表示。
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9.发明授权Method for the three-dimensional representation of a moving structure by a tomographic method 有权通过断层摄影法对移动结构进行三维表示的方法公开(公告)号：US07899152B2
公开(公告)日：2011-03-01
申请号：US12221938
申请日：2008-08-07
申请人： Jan Boese , Wolfgang Härer , Michael Zellerhoff
发明人： Jan Boese , Wolfgang Härer , Michael Zellerhoff
IPC分类号： A61B6/00
CPC分类号： A61B6/025 , A61B6/027 , A61B6/4441 , A61B6/466 , A61B6/481 , A61B6/503 , A61B6/504 , A61B6/507 , G06T11/006 , G06T2211/404 , G06T2211/412 , G06T2211/436
摘要： The invention relates to a method for a three-dimensional representation of a moving structure by a tomographic method, in which during one recording pass a series of projection recordings is registered by an imaging unit at different recording angles between a start position and an end position, it being possible to reconstruct three-dimensional image data from the projection recordings with the following steps: a) generation of tomosynthesis projection recordings along a tomosynthesis scanning path; b) interpolation of the data of the tomosynthesis projection recordings in accordance with an interpolation algorithm in order to generate a projection data set; c) use of a tomosynthesis reconstruction method on the projection data set in order to generate a tomosynthesis volume image; d) repetition of steps b) and c) for all times of interest, and e) display of tomosynthesis representations from the tomosynthesis volume images.
摘要翻译： 本发明涉及一种用于通过断层摄影方法对运动结构进行三维表示的方法，其中在一次记录通过期间，成像单元以起始位置和结束位置之间的不同记录角度登记一系列投影记录 可以通过以下步骤从投影记录重建三维图像数据：a）沿着断层合成扫描路径生成断层合成投影记录; b）根据插值算法对所述断层合成投影记录的数据进行插值，以生成投影数据集; c）在投影数据集上使用断层合成重建方法，以便产生断层合成体积图像; d）对所有感兴趣的时间重复步骤b）和c），以及e）从断层合成体积图像显示断层合成表示。
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10.发明授权公开(公告)号：US07711083B2
公开(公告)日：2010-05-04
申请号：US11897348
申请日：2007-08-30
申请人： Benno Heigl , Stefan Hoppe , Joachim Hornegger , Ernst-Peter Rührnschopf , Holger Scherl , Bernhard Scholz , Michael Zellerhoff
发明人： Benno Heigl , Stefan Hoppe , Joachim Hornegger , Ernst-Peter Rührnschopf , Holger Scherl , Bernhard Scholz , Michael Zellerhoff
IPC分类号： A61B6/00
CPC分类号： G01N23/046 , A61B6/027 , A61B6/032 , A61B6/4458 , G01N2223/419 , G01N2223/612
摘要： To enable an artifact free reconstruction even in the case of large regions of interest and with scanning paths of below 360°, provision is made for a method, with which a three-dimensional image volume is reconstructed from a number of two-dimensional projection images of a region of interest, which were recorded about the region of interest during a rotation of a recording system, comprising an x-ray source with a focal point and a detector, by calculating the gray scale values of the voxels of the image volume by back projection of the projection images, with which each two-dimensional projection images is composed in each instance from at least two individual projection images to form an extended two-dimensional projection image, with the respectively at least two individual projection images being recorded with a constant relative position between the focal point and the region of interest.
摘要翻译： 为了即使在感兴趣的大区域和360度以下的扫描路径的情况下也能够实现无伪影重建，提供一种方法，利用该方法从多个二维投影图像重建三维图像体积 通过计算图像体积的体素的灰度值，通过计算图像体积的体素的灰度值，记录关于记录系统旋转期间的感兴趣区域的感兴趣区域，其包括具有焦点和检测器的x射线源 投影图像的背投影，每个二维投影图像在每个实例中由至少两个单独的投影图像组成，以形成扩展的二维投影图像，分别具有至少两个单独的投影图像被记录有 焦点和感兴趣区域之间的常数相对位置。
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