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18 条记录 (耗时 0.097 秒)

    Method for producing aminoacids
    2.
    发明申请
    Method for producing aminoacids 审中-公开
    生产氨基酸的方法

    公开(公告)号：US20060117401A1

    公开(公告)日：2006-06-01

    申请号：US10539954

    申请日：2003-12-19

    申请人： Oliver Schmitz ,  Piotr Puzio ,  Astrid Blau ,  Ralf Looser ,  Birgit Wendel ,  Beate Kamlage ,  Gunnar Plesch

    发明人： Oliver Schmitz ,  Piotr Puzio ,  Astrid Blau ,  Ralf Looser ,  Birgit Wendel ,  Beate Kamlage ,  Gunnar Plesch

    IPC分类号： A01H1/00 ,  C07H21/04 ,  C12P13/04 ,  C12N15/87 ,  C12N1/21 ,  C12N1/18 ,  C12N15/82 ,  C12N15/74

    CPC分类号： C12P13/12 ,  C12N9/1014 ,  C12N9/88 ,  C12N15/8251 ,  C12N15/8253

    摘要： The invention relates to a method for producing aminoacids in transgenic organisms. The inventive method consists of the following steps: a) introduction of nucleic acids sequence which codes threonine decomposing protein or lysine decomposing protein or codes threonine decomposing protein and lysine decomposing protein, b) introduction of nucleic acids sequence which improves the decomposition of threonine or lysine or the decomposition of threonine and lysine in the transgenic organisms; c) expression of (a) or (b) nucleic acids sequence in a transgenic organism. In a very useful manner, the nucleic acids sequence is introduced in the step a) of the method, said sequence being selected from: i) the nucleic acids sequence with the sequence present in SEQ ID NO: 1, SEQ ID NO: 11, SEQ ID NO: 13, SEQ ID NO: 15, SEQ ID NO: 17, SEQ ID NO: 19, SEQ ID NO: 21, SEQ ID NO: 23 and/or SEQ ID NO:25; ii) the nucleic acids sequence which is preserved as a result of a degenerate genetic code by re-recording aminoacids sequence present in SEQ ID NO: 2, SEQ ID NO: 12, SEQ ID NO: 14, SEQ ID NO: 16, SEQ ID NO:18, SEQ ID NO:20, SEQ ID NO:22, SEQ ID NO:24 and/or 26; and iii) a derivative of the nucleic add sequence present in SEQ ID NO: 1, SEQ ID NO:11, SEQ ID NO: 13, SEQ ID NO: 15, SEQ ID NO: 17, SEQ ID NO: 19, SEQ ID NO: 21, SEQ ID NO: 23 and/or SEQ ID NO:25 which codes polypeptides with the nucleic acids sequence present in SEQ ID NO: 2, SEQ ID NO: 12, SEQ ID NO: 14, SEQ ID NO: 16, SEQ ID NO: 18, SEQ ID NO:20, SEQ ID NO:22, SEQ ID NO:24 and/or 26 and which comprises at least 50% of homology in terms of aminoacids without reducing the biological activity of polypeptides.

    摘要翻译： 本发明涉及一种在转基因生物中产生氨基酸的方法。 本发明方法包括以下步骤：a）引入编码苏氨酸分解蛋白或赖氨酸分解蛋白或编码苏氨酸分解蛋白和赖氨酸分解蛋白的核酸序列，b）引入改善苏氨酸或赖氨酸分解的核酸序列 或转基因生物中苏氨酸和赖氨酸的分解; c）转基因生物中（a）或（b）核酸序列的表达。 以非常有用的方式，在方法的步骤a）中引入核酸序列，所述序列选自：i）具有SEQ ID NO：1，SEQ ID NO：11中存在的序列的核酸序列， SEQ ID NO：13，SEQ ID NO：15，SEQ ID NO：17，SEQ ID NO：19，SEQ ID NO：21，SEQ ID NO：23和/或SEQ ID NO：25; ii）通过重新记录SEQ ID NO：2，SEQ ID NO：12，SEQ ID NO：14，SEQ ID NO：16，SEQ ID NO：16所示的氨基酸序列，作为简并遗传密码的结果而保存的核酸序列 SEQ ID NO：18，SEQ ID NO：20，SEQ ID NO：22，SEQ ID NO：24和/或26; 和iii）存在于SEQ ID NO：1，SEQ ID NO：11，SEQ ID NO：13，SEQ ID NO：15，SEQ ID NO：17，SEQ ID NO：19，SEQ ID NO：19中的核酸添加序列的衍生物 编码多肽与SEQ ID NO：2，SEQ ID NO：12，SEQ ID NO：14，SEQ ID NO：16中存在的核酸序列的SEQ ID NO：21，SEQ ID NO：23和/或SEQ ID NO：25 ，SEQ ID NO：18，SEQ ID NO：20，SEQ ID NO：22，SEQ ID NO：24和/或26，并且其在氨基酸方面包含至少50％的同源性而不降低多肽的生物学活性。

    Means and Methods for Analyzing a Sample by Means of Chromatography-Mass Spectrometry
    5.
    发明申请
    Means and Methods for Analyzing a Sample by Means of Chromatography-Mass Spectrometry 有权
    通过色谱 - 质谱分析样品的方法和方法

    公开(公告)号：US20080234945A1

    公开(公告)日：2008-09-25

    申请号：US11996777

    申请日：2006-07-25

    申请人： Tilmann B. Walk ,  Ralf Looser ,  Bianca Bethan ,  Michael Manfred Herold ,  Beate Kamlage ,  Oliver Schmitz ,  Jan C Wiemer ,  Alexandre Prokoudine ,  Bennard van Ravenzwaay ,  Werner Mellert ,  Georgia Coelho Palermo Cunba ,  Thomas Ehrhardt ,  Gerhard Krennrich

    发明人： Tilmann B. Walk ,  Ralf Looser ,  Bianca Bethan ,  Michael Manfred Herold ,  Beate Kamlage ,  Oliver Schmitz ,  Jan C Wiemer ,  Alexandre Prokoudine ,  Bennard van Ravenzwaay ,  Werner Mellert ,  Georgia Coelho Palermo Cunba ,  Thomas Ehrhardt ,  Gerhard Krennrich

    IPC分类号： G06F19/00

    CPC分类号： G01N30/8675 ,  G01N30/8668 ,  G01N2030/8813 ,  G01N2030/8818 ,  G01N2030/8822 ,  G06F19/703 ,  G06F19/707

    摘要： The present invention relates to a method for analyzing at least one test sample, wherein said test sample comprises at least one compound, said method comprising the steps of: a) providing at least one test sample comprising at least one compound; b) determining said at least one compound in said test sample whereby raw results are generated; and c) analyzing the raw results obtained in step b), wherein the analysis of said at least one test sample is accompanied by an analysis of at least one reference sample; and wherein the test sample and the reference sample are analyzed in an identical sequence in each step of the method. Moreover, the present invention further encompasses a system for carrying out said method comprising operatively linked to each other: (a) means for determining a compound; (b) means for monitoring process parameters, (c) means for analyzing raw results obtained from the means according to (a), wherein said means for analyzing raw results comprise: (i) a first database comprising raw results received from the means according to (a); (ii) a second database comprising monitored process parameters received from the means according to (b); (iii) a third database comprising rules for evaluating the raw results; and (iv) a fourth database comprising allocated results of identified compounds; wherein at least the second, third and fourth database are operatively linked to the first database.

    摘要翻译： 本发明涉及用于分析至少一种测试样品的方法，其中所述测试样品包含至少一种化合物，所述方法包括以下步骤：a）提供至少一种包含至少一种化合物的测试样品; b）确定所述测试样品中的所述至少一种化合物，从而产生原始结果; 以及c）分析在步骤b）中获得的原始结果，其中所述至少一个测试样品的分析伴随着至少一个参考样品的分析; 并且其中在该方法的每个步骤中以相同的顺序分析测试样品和参考样品。 此外，本发明还包括用于执行所述方法的系统，其包括彼此可操作地连接：（a）用于确定化合物的装置; （b）用于监视过程参数的装置，（c）用于分析根据（a）的装置获得的原始结果的装置，其中所述用于分析原始结果的装置包括：（i）第一数据库，包括从根据 至（a）; （ii）第二数据库，包括从根据（b）的装置接收的监测过程参数; （iii）包含用于评估原始结果的规则的第三数据库; 和（iv）第四个数据库，其中包括所鉴别化合物的分配结果; 其中至少所述第二，第三和第四数据库可操作地链接到所述第一数据库。

    Method of filing a highly repetitive or a jumbo patent application and preparing a patent application
    10.
    发明申请
    Method of filing a highly repetitive or a jumbo patent application and preparing a patent application 审中-公开
    提交高度重复或巨型专利申请并准备专利申请的方法

    公开(公告)号：US20070239475A1

    公开(公告)日：2007-10-11

    申请号：US11644752

    申请日：2006-12-22

    申请人： Stephan Krieger ,  Arno Krotzky ,  Gunnar Plesch ,  Oliver Schmitz ,  Alfons Weig ,  Uwe Pressler

    发明人： Stephan Krieger ,  Arno Krotzky ,  Gunnar Plesch ,  Oliver Schmitz ,  Alfons Weig ,  Uwe Pressler

    IPC分类号： G06Q99/00 ,  G06Q90/00

    CPC分类号： G06Q10/10 ,  G06Q50/18 ,  G06Q50/184 ,  G06Q99/00

    摘要： The present invention is generally related to a method to reduce the cost of filing a repetitive or a jumbo patent application. This can be accomplished by using paragraph identifiers and/or summarizing a part of repetitive disclosure in a table format. The present invention also relates to a method to reduce the cost of filing a repetitive or a jumbo patent application which is based on multiple priority applications. The present invention is further related to a method to reduce the cost of filing a subsequent patent application of a repetitive or a jumbo patent application. The present invention is further related to a method to prepare a patent application using automatic text editing process. The subject methods may be used to maximizing the intellectual property protection while minimizing the cost of preparing patent applications and obtaining patent rights.

    摘要翻译： 本发明通常涉及一种降低重复或巨型专利申请的申请成本的方法。 这可以通过使用段标识符和/或以表格格式汇总重复公开的一部分来实现。 本发明还涉及一种减少提交基于多个优先级应用的重复或巨型专利申请的成本的方法。 本发明还涉及一种降低重复或巨型专利申请的后续专利申请的申请成本的方法。 本发明还涉及使用自动文本编辑处理来准备专利申请的方法。 主题方法可以用于最大化知识产权保护，同时最小化准备专利申请和获得专利权的成本。