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1.发明申请3-(4-HYDROXY-3-METHOXYPHENYL)-1-(4-HYDROXYPHENYL)-1-PROPANONE AND USE THEREOF AS AN ANTIMICROBIAL ACTIVE INGREDIENT 有权3-（4-羟基-3-甲氧基苯基）-1-（4-羟基苯基）-1-丙酮及其作为抗微生物活性成分的用途公开(公告)号：US20100254925A1
公开(公告)日：2010-10-07
申请号：US12670509
申请日：2008-07-14
申请人： Oskar Koch , Gerhard Schmaus
发明人： Oskar Koch , Gerhard Schmaus
CPC分类号： A61K8/35 , A61Q15/00 , A61Q17/005 , C07C45/62 , C07C49/84
摘要： Antimicrobially active 3-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)-1-propanone of the following formula 1 is described, as is a method for producing this compound and the use thereof as an antimicrobial active ingredient.
摘要翻译： 描述了下式1的抗微生物活性3-（4-羟基-3-甲氧基苯基）-1-（4-羟基苯基）-1-丙酮，以及作为抗微生物活性成分的方法 。
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2.发明申请3-(4-HYDROXY-3-METHOXYPHENYL)-1-(4-HYDROXYPHENYL)-1-PROPANONE AND ITS USE AS ANTIOXIDANT 审中-公开3-（4-羟基-3-甲氧基苯基）-1-（4-羟基苯基）-1-丙酮及其作为抗氧化剂公开(公告)号：US20100204343A1
公开(公告)日：2010-08-12
申请号：US12670522
申请日：2008-07-14
申请人： Oskar Koch , Gerhard Schmaus
发明人： Oskar Koch , Gerhard Schmaus
CPC分类号： C07C49/84 , A23L3/3481 , A23V2002/00 , A61K8/35 , A61K2800/522 , A61Q19/00 , C07C45/62 , C07C45/74 , A23V2200/02
摘要： The present invention relates to 3-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)-1-propanone of formula (I) a method for preparation of the compound of formula (I) and its use as an antioxidant in formulations and products.
摘要翻译： 本发明涉及式（I）的3-（4-羟基-3-甲氧基苯基）-1-（4-羟基苯基）-1-丙酮，式（I）化合物的制备方法及其作为 配方和产品中的抗氧化剂。
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3.发明申请COMPOSITIONS COMPRISING FRAGRANCE SUBSTANCES AND NEOPENTYL GLYCOL DIISONONANOATE 审中-公开包含巧克力物质的组合物和二甘醇二异氰酸酯公开(公告)号：US20110104089A1
公开(公告)日：2011-05-05
申请号：US12938137
申请日：2010-11-02
申请人： Ingo Wöhrle , Oskar Koch , Manfred Meier , Gerhard Schmaus
发明人： Ingo Wöhrle , Oskar Koch , Manfred Meier , Gerhard Schmaus
CPC分类号： C11B9/00 , A61K8/375 , A61K2800/88 , A61Q5/06 , A61Q13/00 , A61Q15/00 , A61Q17/04 , A61Q19/00 , A61Q19/10
摘要： The invention relates to the use of neopentyl glycol diisononanoate (CAS No. 27841-07-2) as a fixative for perfume oils or as a fixative for (top note) fragrance substances. The invention also relates to certain compositions containing neopentyl glycol diisononanoate and one or more top note fragrance substances. Furthermore, the invention relates to a method for producing such compositions and (cosmetic) products containing a composition according to the invention. Additionally the invention relates to a method for imparting, intensifying or modifying an odor on the (human) skin. A particular aspect of the present invention relates to the improved adherence of volatile fragrance substances to (human) skin and/or (human) hair. Apart from this the invention relates to a combination (kit) comprising neopentyl glycol diisononanoate and one or more top note fragrance substances.
摘要翻译： 本发明涉及新戊二醇二异壬酸酯（CAS号27841-07-2）作为香料油的固定剂或作为（顶部香料）香料的固定剂的用途。 本发明还涉及含有新戊二醇二异壬酸酯和一种或多种顶级香料物质的某些组合物。 此外，本发明涉及一种生产这种组合物的方法和含有本发明组合物的（化妆品）产品。 此外，本发明涉及一种赋予（强化）或改变（人）皮肤上的气味的方法。 本发明的特定方面涉及挥发性芳香物质对（人）皮肤和/或（人）头发的粘附性的改善。 除此之外，本发明涉及包含新戊二醇二异壬酸酯和一种或多种顶级香料物质的组合（试剂盒）。
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4.发明授权3-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)-1-propanone and use thereof as an antimicrobial active ingredient 有权3-（4-羟基-3-甲氧基苯基）-1-（4-羟基苯基）-1-丙酮及其作为抗微生物活性成分的用途公开(公告)号：US08115033B2
公开(公告)日：2012-02-14
申请号：US12670509
申请日：2008-07-14
申请人： Oskar Koch , Gerhard Schmaus
发明人： Oskar Koch , Gerhard Schmaus
CPC分类号： A61K8/35 , A61Q15/00 , A61Q17/005 , C07C45/62 , C07C49/84
摘要： Antimicrobially active 3-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)-1-propanone of the following formula 1 is described, as is a method for producing this compound and the use thereof as an antimicrobial active ingredient.
摘要翻译： 描述了下式1的抗微生物活性3-（4-羟基-3-甲氧基苯基）-1-（4-羟基苯基）-1-丙酮，以及作为抗微生物活性成分的方法 。
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5.发明申请3-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)-1-propanone and its use in cosmetic and pharmaceutical preparations 审中-公开3-（4-羟基-3-甲氧基苯基）-1-（4-羟基苯基）-1-丙酮及其在化妆品和药物制剂中的用途公开(公告)号：US20090208434A1
公开(公告)日：2009-08-20
申请号：US12388030
申请日：2009-02-18
申请人： Gerhard Schmaus , Oskar Koch
发明人： Gerhard Schmaus , Oskar Koch
IPC分类号： A61K8/35 , A61K31/12 , C07C49/255
CPC分类号： A61K31/12 , A61K8/046 , A61K8/35 , A61K2800/874 , A61Q5/02 , A61Q15/00 , A61Q17/04 , A61Q19/00 , A61Q19/004 , A61Q19/02 , A61Q19/04
摘要： The present invention concerns applications of the compound of formula 1 in cosmetic or pharmaceutical preparations.
摘要翻译： 本发明涉及式1化合物在化妆品或药物制剂中的应用。
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6.发明授权Use of dihydrodehydrodiisoeugenol and preparations comprising dihydrodehydrodiisoeugenol 有权使用二氢脱氢二异丁烯醇和包含二氢脱氢二异丁香酚的制剂公开(公告)号：US09066880B2
公开(公告)日：2015-06-30
申请号：US13639646
申请日：2010-04-08
申请人： Imke Meyer , Oskar Koch , Jean Krutmann
发明人： Imke Meyer , Oskar Koch , Jean Krutmann
IPC分类号： A61K8/49 , A61K31/343 , A61K45/06 , A61Q90/00 , A61Q19/08 , A61Q1/10 , A61Q5/00 , A61Q5/02 , A61Q5/06 , A61Q5/12 , A61Q7/00 , A61Q17/04
CPC分类号： A61K8/4973 , A61K31/343 , A61K45/06 , A61K2800/59 , A61K2800/782 , A61K2800/92 , A61Q1/10 , A61Q5/004 , A61Q5/02 , A61Q5/06 , A61Q5/12 , A61Q7/00 , A61Q17/04 , A61Q19/08
摘要： This invention relates to cosmetic and pharmaceutical preparations comprising (i) a diastereomer or a mixture of two or more diastereomers of the compound of formula (I) or (ii) a salt of a diastereomer or of a mixture of two or more diastereomers of the compound of formula (I) or (iii) a mixture of two or more salts of a diastereomer or of a mixture of two or more diastereomers of the compound of formula (I), a diastereomer, salt or a mixture as defined above as a drug for topical application and/or for the treatment of lipoatrophy; the non-therapeutic use of a diastereomer, salt or a mixture as defined above for the prevention, treatment or reduction of skin aging, especially skin wrinkles; the use of a diastereomer, salt or a mixture as defined above for the production of an orally administered non-pharmaceutical preparation.
摘要翻译： 本发明涉及化妆品和药物制剂，其包含（i）式（I）化合物的非对映异构体或两种或更多种非对映体的混合物或（ii）非对映异构体的盐或两种或更多种非对映异构体的混合物 式（I）化合物或（iii）两种或更多种非对映异构体盐或两种或更多种式（I）化合物的非对映异构体的混合物的混合物，如上所定义的非对映异构体，盐或混合物 用于局部应用和/或治疗脂肪萎缩的药物; 如上定义的非对映异构体，盐或混合物的非治疗用途，用于预防，治疗或减少皮肤老化，特别是皮肤皱纹; 使用如上定义的非对映异构体，盐或混合物来生产口服非药物制剂。
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公开(公告)号：US20080050319A1
公开(公告)日：2008-02-28
申请号：US11568606
申请日：2005-04-26
申请人： Oskar Koch , William Johncock
发明人： Oskar Koch , William Johncock
摘要： The use of a compound of the formula wherein R1-R3 independently of one another are hydrogen, C1-C8-alkyl or C1-C8-alkoxy, R4 is COR, CO2R, CONR2, where R is C1-C8-alkyl or C3-C8-cycloalkyl R5 is H or C1-C8-alkyl, R6 is aryl, aryl substituted by up to three C1-C8-alkyl- or C1-C8-alkoxy, or C3-C8-cycloalkyl as UV filters in cosmetic formulations, in particular in combination with UV filters from the group consisting of methoxycinnamate derivatives and/or dibenzoylmethane derivatives, with the proviso that R5 is H if R4 is COR, is described.
摘要翻译： 使用下式化合物其中R 1〜R 3彼此独立地为氢，C 1 -C 8烷基 C 1 -C 6烷基或C 1 -C 8 - 烷氧基，R 4是COR，CO 2 CO 2， R，CONR 2，其中R是C 1 -C 8 - 烷基或C 3 -C 3 > 8个环烷基R 5是H或C 1 -C 8 - 烷基，R 6 O >是芳基，被至多三个C 1 -C 8 - 烷基 - 或C 1 -C 8 - 取代的芳基， 作为化妆品制剂中的UV过滤剂，特别是与来自甲氧基肉桂酸酯衍生物和/或其盐的UV过滤器组合， 或二苯甲酰甲烷衍生物，条件是如果R 4为COR，则R 5为H。
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公开(公告)号：US20070100160A1
公开(公告)日：2007-05-03
申请号：US11553770
申请日：2006-10-27
CPC分类号： C07C29/88 , C07B2200/09 , C07C67/03 , C07C2601/16 , C07C69/78 , C07C69/44 , C07C33/14 , C07C29/56
摘要： Process for esterification of farnesol in an initial mixture comprising alpha-bisabolol, farnesol and optionally other components, with the following steps: 1. Preparation or production of the initial mixture, 2. Adding (i) a transesterification catalyst and (ii) one or more compounds of formula (B) R2YnCO2R1 (B) in which the following applies: R1 stands for an alkyl residue with 1 to 12 C atoms; R2 stands for hydrogen, an alkyl residue with 1 to 20 C atoms, a cycloalkyl residue with 5 to 20 C atoms, an aryl residue with 6 to 20 C atoms or a heteroaryl residue with 5 to 20 C atoms; and Y stands for CH2, CH(Me), CH(Et), C(Me)2, CH2—CH(Me), CH(Me)-CH2 or CH2—CH(Me)-CH2 and n stands for a whole number from 0 to 6; or R2 stands for a group CO2R3, R3 standing for an alkyl residue with 1 to 12 C atoms; and Y stands for CH2, CH(Me), CH(Et), C(Me)2, CH2—CH(Me), CH(Me)-CH2 or CH2—CH(Me)-CH2 and n stands for a whole number from 0 to 8, or Y stands for an optionally substituted phenyl or naphthyl ring with a total of at most four substituents on the ring, n=1 applying.
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公开(公告)号：US06512126B2
公开(公告)日：2003-01-28
申请号：US10001592
申请日：2001-10-19
申请人： Oskar Koch , Walter Kuhn
发明人： Oskar Koch , Walter Kuhn
IPC分类号： C07D30779
CPC分类号： C07D307/83
摘要： Mint lactone can be prepared by hydrogenating hydroxymenthofurolactone to give the intermediate dihydrohydroxymenthofurolactone with the subsequent elimination of water.
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公开(公告)号：US06222076B1
公开(公告)日：2001-04-24
申请号：US09215495
申请日：1998-12-18
申请人： Alfred Krempel , Oskar Koch , Harry Erfurt
发明人： Alfred Krempel , Oskar Koch , Harry Erfurt
IPC分类号： C07C4921
CPC分类号： C07C45/69 , C07C67/293 , C07C69/14
摘要： The invention relates to a novel process for the preparation of hydroxyalkyl- and acyloxyalkyl-substituted cycloketones by free-radical addition of hydroxyalkenes and acyloxyalkenes respectively to cyclic ketones.
摘要翻译： 本发明涉及通过将羟基烯丙基和酰氧基烯基分别自由基加成到环酮中制备羟烷基和酰氧基烷基取代的环酮的新方法。
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