GENE SWITCH COMPOSITIONS AND METHODS OF USE
    3.
    发明申请
    GENE SWITCH COMPOSITIONS AND METHODS OF USE 审中-公开
    基因开关组合物和使用方法

    公开(公告)号:US20140243203A1

    公开(公告)日:2014-08-28

    申请号:US14191859

    申请日:2014-02-27

    IPC分类号: C12N15/82

    CPC分类号: C12N15/8217

    摘要: Compositions and methods relating to the use of sulfonylurea-mediated control of gene expression are provided. Compositions include sulfonylurea responsive chemical switches wherein the gene expression is regulated by a sulfonylurea compound. Compositions also include polynucleotides encoding the polypeptides as well as constructs, vectors, prokaryotic and eukaryotic cells, and eukaryotic organisms including plants and seeds comprising the polynucleotide, and/or produced by the methods. Also provided are methods to regulate expression of a polynucleotide of interest in a cell or organism, and methods to modify a genome, including in a plant or plant cell.

    摘要翻译: 提供了与使用磺酰脲介导的基因表达控制有关的组合物和方法。 组合物包括磺酰脲反应性化学开关,其中基因表达受磺酰脲化合物调节。 组合物还包括编码多肽的多核苷酸以及构建体,载体,原核和真核细胞,以及真核生物,包括包含多核苷酸的植物和种子,和/或由该方法产生的。 还提供了调节细胞或生物体中目的多核苷酸表达的方法,以及修饰基因组(包括植物或植物细胞)的方法。