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14 条记录 (耗时 0.026 秒)

    Hydraulic valve
    1.
    发明授权
    Hydraulic valve 失效
    液压阀

    公开(公告)号：US08505582B2

    公开(公告)日：2013-08-13

    申请号：US13066990

    申请日：2011-04-28

    申请人： Patrick Gautier ,  Marc Hohmann ,  Wolf-Dietmar Schulze ,  Andre Selke ,  Markus Todt

    发明人： Patrick Gautier ,  Marc Hohmann ,  Wolf-Dietmar Schulze ,  Andre Selke ,  Markus Todt

    IPC分类号： F16K11/07

    CPC分类号： F01L1/3442 ,  F01L2001/34426 ,  F01L2001/34433 ,  Y10T137/86702

    摘要： A hydraulic valve for oscillating-motor camshaft adjuster is provided. The valve has a bush and a hollow piston with a piston bottom. The piston is axially movable within the bush by means of an actuator against the force of a screw-type pressure spring. The actuator is applied to the piston bottom. A sleeve secured in the bush is disposed inside the hollow piston and can be displaced relative to the piston. The wall of this sleeve has at least one through-opening, which leads to at least one opening of the hollow piston, which opening can guide a supply pressure (P) applied inside the sleeve alternatively to two sets of pressure chambers of the oscillating-motor camshaft adjuster. The sleeve has a sleeve bottom that seals off the inside space of hollow piston.

    摘要翻译： 提供了一种用于摆动马达凸轮轴调节器的液压阀。 阀具有衬套和具有活塞底部的中空活塞。 活塞可以通过抵抗螺杆式压力弹簧的力的致动器在衬套内轴向移动。 致动器被施加到活塞底部。 固定在衬套中的套筒设置在中空活塞的内部并且可相对于活塞移位。 该套筒的壁具有至少一个通孔，其通向中空活塞的至少一个开口，该开口可将套筒内施加的供应压力（P）引导至两组振荡 - 电机凸轮轴调节器。 套筒具有密封中空活塞的内部空间的套筒底部。

    Hydraulic valve
    2.
    发明申请
    Hydraulic valve 失效
    液压阀

    公开(公告)号：US20110266479A1

    公开(公告)日：2011-11-03

    申请号：US13066990

    申请日：2011-04-28

    申请人： Patrick Gautier ,  Marc Hohmann ,  Wolf-Dietmar Schulze ,  Andre Selke ,  Markus Todt

    发明人： Patrick Gautier ,  Marc Hohmann ,  Wolf-Dietmar Schulze ,  Andre Selke ,  Markus Todt

    IPC分类号： F16K21/00

    CPC分类号： F01L1/3442 ,  F01L2001/34426 ,  F01L2001/34433 ,  Y10T137/86702

    摘要： The invention relates to a hydraulic valve for oscillating-motor camshaft adjuster The valve has a bush and a hollow piston with a piston bottom. The piston is axially movable within the bush by means of an actuator against the force of a screw-type pressure spring. The actuator is applied to the piston bottom. A sleeve secured in the bush is disposed inside the hollow piston and can be displaced relative to the piston. The wall of this sleeve has at least one through-opening, which leads to at least one opening of the hollow piston, which opening can guide a supply pressure (P) applied inside the sleeve alternatively to two sets of pressure chambers of the oscillating-motor camshaft adjuster. The sleeve has a sleeve bottom that seals off the inside space of hollow piston.

    摘要翻译： 本发明涉及一种用于振动电动机凸轮轴调节器的液压阀。该阀具有衬套和具有活塞底部的中空活塞。 活塞可以通过抵抗螺杆式压力弹簧的力的致动器在衬套内轴向移动。 致动器被施加到活塞底部。 固定在衬套中的套筒设置在中空活塞的内部并且可相对于活塞移位。 该套筒的壁具有至少一个通孔，其通向中空活塞的至少一个开口，该开口可将套筒内施加的供应压力（P）引导至两组振荡 - 电机凸轮轴调节器。 套筒具有密封中空活塞的内部空间的套筒底部。

    Pyrrole amides and therapeutic use thereof
    4.
    发明授权
    Pyrrole amides and therapeutic use thereof 失效
    吡咯酰胺及其治疗用途

    公开(公告)号：US4329343A

    公开(公告)日：1982-05-11

    申请号：US228053

    申请日：1981-01-26

    申请人： Claude Bernhart ,  Jean P. Gagnol ,  Patrick Gautier

    发明人： Claude Bernhart ,  Jean P. Gagnol ,  Patrick Gautier

    IPC分类号： C07D207/32 ,  C07D207/327 ,  C07D487/04 ,  A61K31/535 ,  A61K31/40 ,  C07D413/06

    CPC分类号： C07D207/327 ,  C07D487/04 ,  Y10S514/821 ,  Y10S514/822

    摘要： The present invention relates to new derivatives of pyrrole of formula: ##STR1## in which: R.sub.1 represents an atom of hydrogen, a lower alkyl group, a phenyl radical or a pyridyl-2 radical,R.sub.2 represents an atom of hydrogen or a lower alkyl radicalR.sub.3 and R.sub.4 represent a lower alkyl or cycloalkyl radical or the radical ##STR2## is a heterocyclic amine radical, and n is equal to 2 or 3;The invention concerns drugs having an antiarrhythmic activity and an activity as blood platelet anti-aggregant, containing said derivatives.

    摘要翻译： 本发明涉及式（I）的吡咯的新衍生物，其中：R1表示氢原子，低级烷基，苯基或吡啶基-2基团，R2表示氢原子或 低级烷基R3和R4代表低级烷基或环烷基，或者基团“IMAGE”是杂环胺基，n等于2或3; 本发明涉及含有所述衍生物的具有抗心律不齐活性和作为血小板抗聚集剂的活性的药物。

    4-amidino pyrano (3,2-c) pyridine derivatives, and pharmaceutical compositions containing them
    6.
    发明授权
    4-amidino pyrano (3,2-c) pyridine derivatives, and pharmaceutical compositions containing them 失效
    4-脒基吡喃并（3,2-c）吡啶衍生物，以及含有它们的药物组合物

    公开(公告)号：US5185345A

    公开(公告)日：1993-02-09

    申请号：US850994

    申请日：1992-03-12

    申请人： Georges Garcia ,  Patrick Gautier ,  Dino Nisato ,  Richard Roux

    发明人： Georges Garcia ,  Patrick Gautier ,  Dino Nisato ,  Richard Roux

    IPC分类号： C07D405/04 ,  C07D491/04 ,  C07D491/052

    CPC分类号： C07D405/04 ,  C07D491/04

    摘要： The present invention deals with 4-amidino chroman and 4-amidino pyrano (3,2-c) pyridine derivatives, a process for their preparation and pharmaceutical compositions containing them. Said derivatives have antihypertensive and antiarythmic activities. They respond to formula ##STR1## in which: A+B.dbd.--CH.dbd.CH--CH.dbd.N-- ou --CH.dbd.CR.sub.4 --CR.sub.5 .dbd.CH--; X.dbd.N,N.fwdarw.O, C--Z;R.sub.1 .dbd.H, CN, NO.sub.2, C.sub.1 -C.sub.4, alkyl, OH, C.sub.1 -C.sub.4 alkoxy, CF.sub.3 CO--, CH.sub.3 --SO.sub.2 --, .rho.--SO.sub.2 --;R.sub.2 .dbd.H;R.sub.3 .dbd.OH ou OCOCH.sub.3 ou R.sub.2 +R.sub.3 .dbd.double bond.

    摘要翻译： 本发明涉及4-脒基色满和4-脒基吡喃（3,2-c）吡啶衍生物，其制备方法和含有它们的药物组合物。 所述衍生物具有抗高血压和抗血栓活性。 它们响应式（I）其中：A + B = -CH = CH-CH = N-O -CH = CR4-CR5 = CH-; X = N，N-> O，C-Z; R1 = H，CN，NO2，C1-C4，烷基，OH，C1-C4烷氧基，CF3CO-，CH3-SO2-， R2 = H; R3 = OH o OCOCH3 ou R2 + R3 =双键。

    Derivatives of .gamma.-butyrolactone with an anti-arrythmic activity and compositions
    10.
    发明授权
    Derivatives of .gamma.-butyrolactone with an anti-arrythmic activity and compositions 失效
    具有抗arrythmic活性和组成的γ-丁内酯的衍生物

    公开(公告)号：US4542134A

    公开(公告)日：1985-09-17

    申请号：US543898

    申请日：1983-10-20

    申请人： Claude Bernhart ,  Werner Cautreels ,  Patrick Gautier

    发明人： Claude Bernhart ,  Werner Cautreels ,  Patrick Gautier

    IPC分类号： A61K31/341 ,  A61K31/443 ,  A61P9/06 ,  C07D213/57 ,  C07D405/04 ,  C07D405/12 ,  C07D405/14 ,  C07D413/14 ,  A61K31/44 ,  A61K31/535

    CPC分类号： C07D405/04 ,  C07D213/57 ,  C07D405/12 ,  C07D413/14

    摘要： The present invention relates to the products of general formula: ##STR1## in which: R represents a straight or branched alkyl group having from 2 to 5 atoms of carbon, or the group ##STR2## represents a morpholino or piperidino group possibly substituted by 1 or 2 methyl groups;n=2 or 3;R.sub.1 and R.sub.2 considered independently each represent hydrogen or a lower alkyl group (1 to 4 carbon atoms) or R.sub.1 and R.sub.2 taken together represent a (CH.sub.2).sub.m group where m=4 or 5, R.sub.3 being equal to H or R.sub.1 is H and R.sub.2 and R.sub.3 considered together represent (CH.sub.2).sub.p where p is 3 or 4the butyrolactone cycle substitutes the pyridyl group in 2', 3' or 4' position,the salts, isomers and mixtures of isomers of said products; and to a process for preparing said products and to the myocardium-protecting drugs containing same.

    摘要翻译： 本发明涉及以下通式的产物：其中：R表示具有2至5个碳原子的直链或支链烷基，或者“IMAGE”组可表示吗啉代或哌啶子基 被1或2个甲基取代; n = 2或3; 独立地考虑的R 1和R 2各自表示氢或低级烷基（1至4个碳原子），或者R 1和R 2一起表示（CH 2）m基团，其中m = 4或5，R 3等于H或R 1为H， R2和R3一起代表（CH2）p，其中p是3或4，丁内酯循环代替2'，3'或4'位的吡啶基，所述产物的盐，异构体和异构体的混合物; 以及制备所述产品的方法和含有其的心肌保护药物的方法。