System and method for centralized clearing of over the counter foreign exchange instruments
    2.
    发明申请
    System and method for centralized clearing of over the counter foreign exchange instruments 审中-公开
    集中清算柜台外汇兑换工具的制度和方法

    公开(公告)号:US20070118459A1

    公开(公告)日:2007-05-24

    申请号:US11590540

    申请日:2006-10-31

    IPC分类号: G06Q40/00

    CPC分类号: G06Q40/04 G06Q40/00

    摘要: The disclosed systems and methods relate to allowing trading of over the counter (“OTC”) foreign exchange (“FX”) contracts on a centralized matching and clearing mechanism, such as that of the Chicago Mercantile Exchange's (“CME”'s) futures exchange system (the “Exchange”). The disclosed systems and methods allow for anonymous transactions, centralized clearing, efficient settlement and the provision of risk management/credit screening mechanisms to lower risk, reduce transaction costs and improve the liquidity in the FX market place. In particular, the disclosed embodiments increase speed of execution facilitating growing demand for algorithmic trading, increased price transparency, lower cost of trading, customer to customer trading, and automated asset allocations, recurring trades as well as clearing and settlement efficiencies.

    摘要翻译: 所披露的系统和方法涉及允许在集中式配对清算机制(例如芝加哥商品交易所(CME))期货交易柜台(“OTC”)外汇交易(“外汇”)合约 交换系统(“交换”)。 所披露的系统和方法允许匿名交易,集中清算,有效结算和提供风险管理/信用审查机制,降低风险,降低交易成本,提高外汇市场的流动性。 特别地,所公开的实施例增加执行速度,促进对算法交易的日益增长的需求,增加的价格透明度,降低交易成本,客户到客户交易以及自动资产分配,经常性交易以及结算和结算效率。

    Reagens for the detection of protein acetylation signaling pathways
    4.
    发明申请
    Reagens for the detection of protein acetylation signaling pathways 审中-公开
    用于检测蛋白质乙酰化信号通路的试剂

    公开(公告)号:US20090325312A1

    公开(公告)日:2009-12-31

    申请号:US12227320

    申请日:2007-05-11

    IPC分类号: G01N33/566 C07K16/18

    CPC分类号: G01N33/6842 C07K16/44

    摘要: The invention discloses 426 novel acetylation sites identified in signal transduction proteins and pathways underlying human protein acetylation signaling pathways, and provides acetylation-site specific antibodies and heavy-isotope labeled peptides (AQUA peptides) for the selective detection and quantification of these acetylated sites/proteins, as well as methods of using the reagents for such purpose. Among the acetylation sites identified are sites occurring in the following protein types: Methyltransferases, Transcription factors, Transcription coactivators, Translation initiation complex proteins, Oxireductases, Protein kinases, RNA binding proteins, Secreted proteins, Transferases, Transporter proteins, Ubiquitin conjugating system proteins, Motor proteins, Phosphotases, Proteases, Phospholipases, Receptor proteins and Vesicle proteins.

    摘要翻译: 本发明公开了在信号转导蛋白中鉴定的426个新的乙酰化位点和人蛋白质乙酰化信号通路的途径,并提供乙酰化位点特异性抗体和重同位素标记肽(AQUA肽),用于选择性检测和定量这些乙酰化位点/蛋白质 ,以及使用试剂用于此目的的方法。 确定的乙酰化位点之间的位点是发生在以下蛋白质类型中的位点:甲基转移酶,转录因子,转录共激活因子,翻译起始复合蛋白​​,氧化还原酶,蛋白激酶,RNA结合蛋白,分泌蛋白,转移酶,转运蛋白,泛素缀合系统蛋白,马达 蛋白质,磷酸酶,蛋白酶,磷脂酶,受体蛋白和囊泡蛋白。

    Oblong Throwing Ball with Central Passage
    6.
    发明申请
    Oblong Throwing Ball with Central Passage 审中-公开
    中央通道长方形投掷球

    公开(公告)号:US20150005116A1

    公开(公告)日:2015-01-01

    申请号:US13927172

    申请日:2013-06-26

    IPC分类号: A63B37/02

    摘要: A throwable ball having a large internal passage aligned with its central axis. An insert defines the bounds of the internal passage. This insert is surrounded by compressible foam that gives the ball an easy gripping surface. Interlock features are preferably provided between the insert and the compressible foam so that they do not slip relative to each other.

    摘要翻译: 具有与其中心轴对准的大内部通道的可抛掷球。 插入物定义内部通道的界限。 该插入物被可压缩泡沫包围,使球体容易抓握表面。 互锁特征优选地设置在插入件和可压缩泡沫之间,使得它们不相对于彼此滑动。