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    Compounds for PDT
    1.
    发明授权
    Compounds for PDT 失效
    PDT化合物

    公开(公告)号：US07375215B2

    公开(公告)日：2008-05-20

    申请号：US10221218

    申请日：2001-03-08

    申请人： Paul Bradley ,  Mehar Manku

    发明人： Paul Bradley ,  Mehar Manku

    IPC分类号： C07D487/22 ,  C07D47/00 ,  C08G18/08 ,  A01N55/02 ,  A61K31/409 ,  A61K31/555

    CPC分类号： C07D487/22 ,  A61K41/0071

    摘要： A tetrakis(hydroxyphenyl)chlorin, bacteriochlorin or isobacteriochlorin, derivatised at one or more of the hydroxy groups by addition reaction with a diisocyanate, diisothiocyanate or isocyanate-isothiocyanate at one isocyanate or isothiocyanate group thereof, the other isocyanate or isothiocyanate group being itself derivatised by addition reaction with the hydroxy group of an w-alkylated or acylated poly(alkylene oxide) or to a hydroxy group of a link residue itself carrying a residue of such poly(alkylene oxide).

    摘要翻译： 通过与二异氰酸酯，二异硫氰酸酯或异氰酸酯 - 异硫氰酸酯在一个异氰酸酯或异硫氰酸酯基团的加成反应，在一个或多个羟基衍生的四（羟基苯基）二氢卟酚，细菌二氢卟酚或异细菌素，其它异氰酸酯或异硫氰酸酯基团本身由 与w-烷基化或酰化的聚（环氧烷）的羟基或本身携带这种聚（环氧烷）的残基的连接残基的羟基的加成反应。

    Compounds for pdt
    4.
    发明申请
    Compounds for pdt 失效
    化合物pdt

    公开(公告)号：US20060040912A1

    公开(公告)日：2006-02-23

    申请号：US10221218

    申请日：2001-03-08

    申请人： Paul Bradley ,  Mehar Manku

    发明人： Paul Bradley ,  Mehar Manku

    IPC分类号： C07D487/22 ,  A61K31/555 ,  A61K31/409

    CPC分类号： C07D487/22 ,  A61K41/0071

    摘要： A tetrakis(hydroxyphenyl)chlorin, bacteriochlorin or isobacteriochlorin, derivatised at one or more of the hydroxy groups by addition reaction with a diisocyanate, diisothiocyanate or isocyanate-isothiocyanate at one isocyanate or isothiocyanate group thereof, the other isocyanate or isothiocyanate group being itself derivatised by addition reaction with the hydroxy group of an w-alkylated or acylated poly(alkylene oxide) or to a hydroxy group of a link residue itself carrying a residue of such poly(alkylene oxide).

    摘要翻译： 通过与二异氰酸酯，二异硫氰酸酯或异氰酸酯 - 异硫氰酸酯在一个异氰酸酯或异硫氰酸酯基团的加成反应，在一个或多个羟基衍生的四（羟基苯基）二氢卟酚，细菌二氢卟酚或异细菌素，其它异氰酸酯或异硫氰酸酯基团本身由 与w-烷基化或酰化的聚（环氧烷）的羟基或本身携带这种聚（环氧烷）的残基的连接残基的羟基的加成反应。

    System and methods for processing and displaying aggregate status events for remote nodes
    7.
    发明授权
    System and methods for processing and displaying aggregate status events for remote nodes 有权
    用于处理和显示远程节点聚合状态事件的系统和方法

    公开(公告)号：US07603458B1

    公开(公告)日：2009-10-13

    申请号：US10674322

    申请日：2003-09-30

    申请人： John C. Sexton ,  Paul Bradley ,  Hanna Yehuda ,  David Barta

    发明人： John C. Sexton ,  Paul Bradley ,  Hanna Yehuda ,  David Barta

    IPC分类号： G06F15/173

    CPC分类号： H04L41/065 ,  H04L41/0213 ,  H04L41/046 ,  H04L41/0681 ,  H04L41/142 ,  H04L41/22 ,  H04L43/0817

    摘要： A status monitoring and reporting mechanism which distinguishes more significant events and prominently displays events pertaining to nodes, interconnections, and other network entities which may present problems, and to suppresses benign messages which may not require immediate attention, provides an “at a glance” view of overall system health. By processing and displaying aggregate status events from a plurality of agent components to highlight the most severe and critical events from among a large volume of general status events allows an operator to quickly diagnose potential problems before detrimental results occur, and helps maintain a general efficient system health by isolating less efficient areas to allow for timely remedial action prior to failure. Various agents disseminated in a storage area network determine and report status events back to a central server. The server receives, aggregates, and processes the status events to display a status array indicative of overall system health.

    摘要翻译： 区分更重要事件并显着地显示有关可能存在问题的节点，互连和其他网络实体的事件以及抑制可能不需要立即注意的良性消息的状态监视和报告机制提供了“一目了然”视图 的整体系统健康。 通过处理和显示来自多个代理组件的聚合状态事件以突显来自大量一般状态事件中的最严重和关键的事件，允许操作者在有害的结果发生之前快速诊断潜在问题，并且有助于维持一般的有效系统 通过隔离效率较低的领域，以便在失败之前及时采取补救措施来保护健康。 在存储区域网络中传播的各种代理确定并将状态事件报告回中央服务器。 服务器接收，聚合和处理状态事件以显示指示整个系统运行状况的状态数组。

    General matching network for acoustic wave filters and acoustic resonators
    8.
    发明申请
    General matching network for acoustic wave filters and acoustic resonators 有权
    声波滤波器和声谐振器的通用匹配网络

    公开(公告)号：US20080042778A1

    公开(公告)日：2008-02-21

    申请号：US11505453

    申请日：2006-08-17

    申请人： Tiberiu Jamneala ,  Paul Bradley ,  Michael Frank

    发明人： Tiberiu Jamneala ,  Paul Bradley ,  Michael Frank

    IPC分类号： H03H9/70

    CPC分类号： H03H9/706 ,  H03H9/0004

    摘要： A method and circuit matches a device to n filters, wherein each filter is a SAW filter, BAW filter, or FBAR filter. The method and system: (a) provide an inductor or transmission line connected between a common terminal and ground; (b) provide a plurality of capacitance values (C1m, C2m, . . . , Cnm) each corresponding to one of the n filters; and (c) for each of the n filters, directly connect a first terminal of the filter to either: (1) the common terminal, or (2) a first terminal of a corresponding capacitor having the correspondence capacitance value calculated in step (b), where a second terminal of the corresponding capacitor is directly connected to the common terminal.

    摘要翻译： 方法和电路将器件与n个滤波器相匹配，其中每个滤波器是SAW滤波器，BAW滤波器或FBAR滤波器。 方法和系统：（a）提供连接在公共端子和地之间的电感器或传输线; （b）提供多个电容值（C 1m 2，C 2 m，...，C nm），每个对应于 n过滤器 和（c）对于n个滤波器中的每一个，直接将滤波器的第一端连接到：（1）公共端子，或者（2）具有在步骤（b）中计算的对应电容值的相应电容器的第一端子 ），其中相应电容器的第二端子直接连接到公共端子。

    Compounds useful in therapy
    9.
    发明申请
    Compounds useful in therapy 失效
    化合物可用于治疗

    公开(公告)号：US20070105909A1

    公开(公告)日：2007-05-10

    申请号：US11592574

    申请日：2006-11-03

    申请人： Paul Bradley ,  Kevin Dack ,  Patrick Johnson ,  Sarah Skerratt

    发明人： Paul Bradley ,  Kevin Dack ,  Patrick Johnson ,  Sarah Skerratt

    IPC分类号： A61K31/4439 ,  A61K31/4152 ,  C07D403/02 ,  C07D231/12

    CPC分类号： C07D231/18 ,  C07D401/12

    摘要： Compounds of formula (I), or a pharmaceutically acceptable derivative thereof, wherein R1 and R3 independently represent H, C1-6alkyl, C3-8cycloalkyl, or halogen; R2 represents C1-6alkyl, CF3 or aryl; a represents 1 or 2; R4, R5, R7 and R8 independently represent H, C1-6alkyl, C1-6alkyloxy, CN or halogen, or R4 and R5, or R7 and R8, together with the ring to which they are attached form an aryl or heterocyclic fused ring system; X represents C or N; Y represents CH2 or O; R6 represents H, CN or halo provided that, when X represents N, R6 is absent. The compounds are useful for treating endometriosis, uterine fibroids (leiomyomata), menorrhagia, adenomyosis, primary and secondary dysmenorrhoea (including symptoms of dyspareunia, dyschexia and chronic pelvic pain), or chronic pelvic pain syndrome.

    摘要翻译： 式（I）化合物或其药学上可接受的衍生物，其中R 1和R 3独立代表H，C 1-6烷基 C 3-8环烷基或卤素; R 2表示C 1-6烷基，CF 3或芳基; a代表1或2; R 4，R 5，R 7和R 8独立地表示H，C 1-6 C 1-6烷基，C 1-6烷氧基，CN或卤素，或R 4和R 5或R 7 和它们所连接的环连接形成芳基或杂环稠环体系; X表示C或N; Y表示CH 2或O; R 6表示H，CN或卤素，条件是当X表示N时，R 6不存在。 这些化合物可用于治疗子宫内膜异位症，子宫肌瘤（平滑肌瘤），月经过多，子宫腺肌症，原发性和继发性痛经（包括性交疼痛，dyschexia和慢性盆腔疼痛症状）或慢性盆腔疼痛综合征。