摘要:
A method of producing analgesia and enhancing analgesia is disclosed. The method includes administering a beta-neurotoxin that is characterized by its ability to bind to pre- and postsynaptic receptors resulting in the inhibition of neurotransmission.
摘要:
A composition of matter for an analgesia and its method of use is disclosed. The method of use is for the treatment of chronic pain, especially to the treatment of heretofore intractable pain as associated with advanced cancer. The pain associated with neurological conditions, rheumatoid arthritis, viral infections and lesions is also contemplated. The method includes administering to a host an alpha-neurotoxin that is characterized by its ability to blocking of the action of acetylcholine at nicotinic acetylcholine receptors.
摘要:
Disclosed a pharmaceutical composition including one of crotoxin, mojavetoxin or a related toxin and a carrier for use in the treatment of chronic pain, especially to the treatment of heretofore intractable pain such as that associated with advanced cancer wherein the treatment is independent of the reduction of tumors. The crotoxin is preferably obtained from the snake Crotalus durissus terrificus and the mojavetoxin is obtained from the rattlesnake Crotalus scutulatus scutulatus. Preferably the composition further comprises an effective amount of acetylsalicylic acid whereby the toxin and acetylsalicylic acid together produce a synergistic effect providing enhanced pain relief. The composition of the invention may be delivered in parenteral (i.p.) (intravenous, intramuscular or subcutaneous) applications. Alternatively, the composition may be applied as a topical application. The biological activity of the composition is characterized by its ability to bind to presynaptic and postsynapic receptor sites. This results in an inhibition of aceylcholine release and activity.
摘要:
A touch-sensing device has a top and a bottom surface. A grounded connector is coupled to the bottom surface of the touch-sensing device and extends through the touch-sensing device to the top surface of the touch-sensing device. The touch-sensing device has a grounded layer. A first dielectric layer is on the grounded layer. A conductive layer of the touch-sensing device has an opening. The conductive layer is on the first dielectric layer. The second dielectric layer is on the conductive layer. The grounded connector is coupled to the grounded layer and extends through the opening of the conductive layer to the top surface of the second dielectric layer.
摘要:
A switch circuit and method is described. In one embodiment, the switch circuit is configured to couple each of a plurality of plurality of capacitive sense elements and a plurality of capacitance sensors in different modes. In a first mode, the switch circuit is configured to couple each of the plurality of capacitance sensors to a group of two or more of the plurality of capacitive sense elements. In a second mode, the switch circuit is configured to couple the plurality of capacitance sensors to individual ones of the two or more of the plurality of capacitive sense elements in one of the groups.
摘要:
A touchpad has interleaved conductive traces across a touchpad surface. Each conductive trace has a first end and a second end. The width of the first end is larger than the width of the second end. The interleaved conductive traces have a first group of conductive traces alternated with a second group of conductive traces.
摘要:
In at least one implementation, a structural rail for a vehicle includes a main body and a front portion. The main body has an upper wall, a lower wall, an inner sidewall and an outer sidewall spaced from the inner sidewall. The front portion has a rear end adjacent to the second end of the main body and a front end spaced from the rear end. The main body has a first bend between the first end and second end so that a portion of the main body is angled outwardly and an included angle of less than 180 degrees is provided in the outer sidewall. The rail also includes a second bend between the first bend and the front end, and the second bend further angles at least part of the front portion outwardly relative to the outwardly angled portion of the main body.
摘要:
An apparatus and method for setting a ratio of a discharge rate to a charge rate for measuring a capacitance on a sensor element of a sensing device. The apparatus may include a sensor element of a sensing device, a relaxation oscillator having a first and a second programmable current source, and a ratio decoder to receive a ratio of a discharge rate to a charge rate, and to set the first and second programmable current sources based on the received ratio.
摘要:
A touch-sensing device has a top and a bottom surface. A grounded connector is coupled to the bottom surface of the touch-sensing device and extends through the touch-sensing device to the top surface of the touch-sensing device. The touch-sensing device has a grounded layer. A first dielectric layer is on the grounded layer. A conductive layer of the touch-sensing device has an opening. The conductive layer is on the first dielectric layer. The second dielectric layer is on the conductive layer. The grounded connector is coupled to the grounded layer and extends through the opening of the conductive layer to the top surface of the second dielectric layer.
摘要:
A method and apparatus to implement a touch-sensor device using shared capacitive sensors. The apparatus includes a first plurality of sensor elements coupled together, a second plurality of sensor elements coupled together independently of the first plurality of sensor elements, and a third plurality of sensor elements coupled together independently of the first and second pluralities of sensor elements. The sensor elements of the first, second, and third pluralities of sensor elements are interspersed and disposed in a repetitive sequence along a movement path of a conductive object.