摘要:
A compact, lightweight, portable optical assembly comprising: a platform; and a plurality of optical elements mounted to the platform; wherein the plurality of optical elements are optically connected to one another with free-space couplings so as to form an optical circuit; and further wherein the platform is sufficiently mechanically robust so as to maintain the free-space optical coupling between the various optical elements. A method for making a compact, lightweight, portable optical assembly, comprising: providing a platform; and mounting a plurality of optical elements to the platform; wherein the plurality of optical elements are mounted to the platform so that they are optically connected to one another with free-space couplings so as to form an optical circuit; and further wherein the platform is sufficiently mechanically robust so as to maintain the free-space optical coupling between the various optical elements.
摘要:
In another form of the present invention, there is provided a Raman probe comprising: a first optical fiber for receiving laser excitation light from a light source and transmitting the same; a first filter for receiving light from the first optical fiber and adapted to pass the laser excitation light and to block spurious signals associated with the light; a second filter for receiving light from the first filter and adapted to direct the light toward the specimen; focusing apparatus for receiving the light from the second filter, focusing the light on a specimen so as to generate the Raman signal, and returning the Raman signal to the second filter; wherein the second filter is further configured so that when the second filter receives the Raman signal from the focusing apparatus, the second filter filters out unwanted laser excitation light before directing the Raman signal to a second optical fiber; and a second optical fiber for receiving the Raman signal from the second filter and transmitting the same to a light analyzer. In another form of the present invention, there is provided a Raman probe comprising: a light source for generating laser excitation light; focusing apparatus for receiving the laser excitation light from the light source, focusing the laser excitation light on a specimen so as to generate the Raman signal, and returning the Raman signal to a light analyzer; and a light analyzer for analyzing the Raman signature of the specimen, whereby to identify the specimen; wherein the focusing apparatus is configured to permit the specimen to reside in a vial receptacle or at a target location remote from the vial receptacle. In another form of the present invention, there is provided a method for conducting Raman spectroscopy of a specimen, comprising: generating laser excitation light using a light source; passing the laser excitation light through a first filter so as to block spurious signals associated with the light; passing the laser excitation light through a second filter so as to direct the light toward the specimen; receiving the light from the second filter, focusing the light on a specimen so as to generate the Raman signal, and returning the Raman signal to the second filter; wherein the second filter is further configured so that when the second filter receives the Raman signal from the specimen, the second filter filters out unwanted laser excitation light; passing the filtered light received from the second filter to a light analyzer; and analyzing the Raman signature of the specimen so as to identify the specimen. In another form of the present invention, there is provided a Raman probe comprising: a housing; a light source disposed within the housing for generating laser excitation light; focusing apparatus disposed within the housing for receiving the laser excitation light from the light source, focusing the laser excitation light on a specimen so as to generate the Raman signal, and returning the Raman signal to a light analyzer; and a light analyzer disposed within the housing for analyzing the Raman signature of the specimen, whereby to identify the specimen; wherein the focusing apparatus is configured to permit the specimen to reside at a target location remote from the housing; and further comprising an optical shield mounted to the housing so as to be disposed between the specimen and the user, whereby to optically shield the user from the light source. In another form of the present invention, there is provided a Raman probe comprising: a housing; a light source disposed within the housing for generating laser excitation light; focusing apparatus disposed within the housing for receiving the laser excitation light from the light source, focusing the laser excitation light on a specimen so as to generate the Raman signal, and returning the Raman signal to a light analyzer; and a light analyzer disposed within the housing for analyzing the Raman signature of the specimen, whereby to identify the specimen; wherein the focusing apparatus is configured to permit the specimen to reside at a target location remote from the housing; and further comprising a camera mounted to the housing so that its field of view encompasses the target location, and a display mounted to the housing for displaying the image captured by the camera, whereby to permit the user to position the probe relative to the specimen while watching the display.
摘要:
Disclosed herein are Raman probes that include: (a) a first optical fiber for receiving laser excitation light from a light source and transmitting the same; (b) a first filter for receiving light from the first optical fiber and adapted to pass the laser excitation light and to block spurious signals associated with the light; (c) a second filter for receiving light from the first filter and adapted to direct the light toward a specimen; and (d) focusing apparatus for receiving the light from the second filter, focusing the light on the specimen so as to generate the Raman signal, and returning the Raman signal to the second filter. The second filter is further configured so that when the second filter receives the Raman signal from the focusing apparatus, the second filter filters out unwanted laser excitation light before directing the Raman signal to a second optical fiber.
摘要:
Disclosed herein are Raman probes that include: (a) a first optical fiber for receiving laser excitation light from a light source and transmitting the same; (b) a first filter for receiving light from the first optical fiber and adapted to pass the laser excitation light and to block spurious signals associated with the light; (c) a second filter for receiving light from the first filter and adapted to direct the light toward a specimen; and (d) focusing apparatus for receiving the light from the second filter, focusing the light on the specimen so as to generate the Raman signal, and returning the Raman signal to the second filter. The second filter is further configured so that when the second filter receives the Raman signal from the focusing apparatus, the second filter filters out unwanted laser excitation light before directing the Raman signal to a second optical fiber.
摘要:
The apparatus disclosed herein features: (a) a handheld, portable spectrometer that includes a radiation source configured to direct incident radiation to a sample, a detector configured to receive signal radiation from the sample, and a housing enclosing the radiation source and the detector; (b) an extended member attachable to the housing and having an interior channel to define a path for directing radiation from the source to the sample and for receiving radiation from the sample at the detector; (c) and a vial receptacle configured to hold a different sample and positioned to receive radiation from the source, where the detector is positioned to receive radiation from the different sample and the housing is configured to support the vial receptacle and attach to the extended member at the same time.
摘要:
Disclosed herein are Raman probes that include: (a) a first optical fiber for receiving laser excitation light from a light source and transmitting the same; (b) a first filter for receiving light from the first optical fiber and adapted to pass the laser excitation light and to block spurious signals associated with the light; (c) a second filter for receiving light from the first filter and adapted to direct the light toward a specimen; and (d) focusing apparatus for receiving the light from the second filter, focusing the light on the specimen so as to generate the Raman signal, and returning the Raman signal to the second filter. The second filter is further configured so that when the second filter receives the Raman signal from the focusing apparatus, the second filter filters out unwanted laser excitation light before directing the Raman signal to a second optical fiber.
摘要:
An apparatus includes: a handheld Raman analyzer that can include: a common platform; a laser assembly mounted on a laser platform, the laser platform supported on the common platform by a first material and a second thermally conductive material wherein the first material is softer than the second material; an optical probe head assembly disposed on the common platform, the optical probe head assembly spaced apart from the laser assembly; a spectrometer assembly disposed on the common platform, the spectrometer assembly spaced apart from the optical probe head assembly; and an analysis apparatus configured to identify a specimen based on a Raman signature received from the spectrometer. The laser assembly can be optically coupled to the optical probe head assembly by at least a first free-space coupling region and the optical probe head assembly optically coupled to the spectrometer assembly by at least a second free-space coupling region.
摘要:
Disclosed herein are Raman probes that include: (a) a first optical fiber for receiving laser excitation light from a light source and transmitting the same; (b) a first filter for receiving light from the first optical fiber and adapted to pass the laser excitation light and to block spurious signals associated with the light; (c) a second filter for receiving light from the first filter and adapted to direct the light toward a specimen; and (d) focusing apparatus for receiving the light from the second filter, focusing the light on the specimen so as to generate the Raman signal, and returning the Raman signal to the second filter. The second filter is further configured so that when the second filter receives the Raman signal from the focusing apparatus, the second filter filters out unwanted laser excitation light before directing the Raman signal to a second optical fiber.
摘要:
A method of identifying the presence of heroin in an impure heroin composition which contains heroin and at least one fluorescent contaminant which interferes with a Raman signal from the heroin. The method may include contacting the mixture with a solvent such as an alcohol, then contacting the resulting alcohol composition with a SERS surface. The surface may then be exposed to laser light from a hand-held Raman spectrometer to detect a Raman signal from the heroin. An apparatus for performing the method is also provided.