AUTO-SCALING OF PARAMETRIC IMAGES
    1.
    发明申请
    AUTO-SCALING OF PARAMETRIC IMAGES 有权
    参数图像的自动缩放

    公开(公告)号:US20120082359A1

    公开(公告)日:2012-04-05

    申请号:US13377143

    申请日:2010-06-08

    IPC分类号: G06K9/00

    摘要: An embodiment is proposed for analyzing a body-part. A corresponding embodiment of a data-processing method includes the steps of providing a parametric map including a plurality of parameter values each one characterizing a corresponding location of the body-part, and determining at least one statistical indicator of at least one distribution of a plurality of analysis parameter values corresponding to selected analysis locations, each statistical indicator being indicative of a condition of an analysis region of the body-part defined by the analysis locations. In an embodiment, the step of determining at least one statistical indicator includes, for each distribution of the analysis parameter values, determining a saturation value partitioning an ordered sequence of processing parameter values, corresponding to selected processing locations at least including the analysis locations, into a first subset and a second subset consisting of a number of the processing parameter values being determined according to a predefined auto-scaling percentage, generating an auto-scaled map including, for each processing location, an auto-scaled value being equal to the corresponding processing parameter value if included in the second subset, or the saturation value if the corresponding processing parameter value is included in the first subset, and determining the at least one statistical indicator from the auto-scaled values corresponding to the analysis locations.

    摘要翻译: 提出了用于分析身体部位的实施例。 数据处理方法的相应实施例包括以下步骤:提供包括表征身体部位的对应位置的多个参数值的参数图,以及确定至少一个多个分布的分布的统计指标 对应于所选分析位置的分析参数值,每个统计指标指示由分析位置定义的身体部分的分析区域的状况。 在一个实施例中,确定至少一个统计指示符的步骤包括对于分析参数值的每个分布,确定将对应于至少包括分析位置的所选处理位置的处理参数值的有序序列划分为饱和值, 由根据预定义的自动缩放百分比确定的多个处理参数值组成的第一子集和第二子集,生成自动缩放图,包括对于每个处理位置,自动缩放值等于相应的 如果包括在第二子集中则处理参数值,或者如果相应的处理参数值包括在第一子集中则为饱和值,以及根据与分析位置对应的自动缩放值确定至少一个统计指标。

    GAS-FILLED MICROVESICLES WITH TARGETING LIGAND OR THERAPEUTIC AGENT
    6.
    发明申请
    GAS-FILLED MICROVESICLES WITH TARGETING LIGAND OR THERAPEUTIC AGENT 审中-公开
    具有指定配体或治疗剂的气体填充微血管

    公开(公告)号:US20120093731A9

    公开(公告)日:2012-04-19

    申请号:US12448374

    申请日:2007-12-19

    CPC分类号: A61K49/223

    摘要: Gas-filled microvesicles comprising a boundary envelope containing a gas, wherein said microvesicles comprise: —a first component, bound to said envelope, having binding affinity for an Fc-region of an antibody; and—a second component comprising a Fc-region of an antibody, bound to said first component through said Fc-region, said second component comprising a targeting ligand or a therapeutic agent. Aqueous suspensions of said microvesicles are particularly useful in contrast enhanced ultrasound imaging.

    摘要翻译: 气体填充的微泡包含含有气体的边界包膜,其中所述微泡包含: - 与所述包膜结合的第一组分,对抗体的Fc区具有结合亲和力; 和包含通过所述Fc区结合到所述第一组分的抗体的Fc区的第二组分,所述第二组分包含靶向配体或治疗剂。 所述微泡的水性悬浮液在增强超声成像的对比中是特别有用的。

    GAS-FILLED MICROVESICLES WITH TARGETING LIGAND OR THERAPEUTIC AGENT
    7.
    发明申请
    GAS-FILLED MICROVESICLES WITH TARGETING LIGAND OR THERAPEUTIC AGENT 审中-公开
    具有指定配体或治疗剂的气体填充微血管

    公开(公告)号:US20100086490A1

    公开(公告)日:2010-04-08

    申请号:US12448374

    申请日:2007-12-19

    CPC分类号: A61K49/223

    摘要: Gas-filled microvesicles comprising a boundary envelope containing a gas, wherein said microvesicles comprise: —a first component, bound to said envelope, having binding affinity for an Fc-region of an antibody; and—a second component comprising a Fc-region of an antibody, bound to said first component through said Fc-region, said second component comprising a targeting ligand or a therapeutic agent. Aqueous suspensions of said microvesicles are particularly useful in contrast enhanced ultrasound imaging.

    摘要翻译: 气体填充的微泡包含含有气体的边界包膜,其中所述微泡包含: - 与所述包膜结合的第一组分,对抗体的Fc区具有结合亲和力; 和包含通过所述Fc区结合到所述第一组分的抗体的Fc区的第二组分,所述第二组分包含靶向配体或治疗剂。 所述微泡的水性悬浮液在增强超声成像的对比中是特别有用的。