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公开(公告)号:US09909990B1
公开(公告)日:2018-03-06
申请号:US15263063
申请日:2016-09-12
Applicant: Photon Systems, Inc.
Inventor: William F. Hug , Rohit Bhartia , Ray D. Reid , Arthur L. Lane
IPC: G01N21/64
CPC classification number: G01N21/64 , G01J3/10 , G01J3/36 , G01J3/44 , G01N21/6486 , G01N21/65 , G01N21/8806 , G01N27/44721 , G01N33/0047 , G01N2021/6421 , G01N2021/6471 , G01N2201/06113 , G01N2201/0612 , G01N2201/062 , G01N2201/126
Abstract: Naphthalene, benzene, toluene, xylene, and other volatile organic compounds VOCs have been identified as serious health hazards. Embodiments of the invention are directed to methods and apparatus for near-real-time in-situ detection and accumulated dose measurement of exposure to naphthalene vapor and other hazardous gaseous VOCs. The methods and apparatus employ excitation of fluorophors native or endogenous to compounds of interest using light sources emitting in the ultraviolet below 300 nm and measurement of native fluorescence emissions in distinct wavebands above the excitation wavelength. The apparatus of some embodiments are cell-phone-sized sensor/dosimeter “badges” to be worn by personnel potentially exposed to hazardous VOCs. The badge sensor of some embodiments provides both real time detection and data logging of exposure to naphthalene or other VOCs of interest from which both instantaneous and accumulated dose can be determined.
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公开(公告)号:US10753863B1
公开(公告)日:2020-08-25
申请号:US16688919
申请日:2019-11-19
Applicant: Photon Systems, Inc.
Inventor: William F. Hug , Ray D. Reid , Rohit Bhartia , Arthur L. Lane
Abstract: Spectroscopic chemical analysis methods and apparatus are disclosed which employ deep ultraviolet (e.g. in the 200 nm to 300 nm spectral range) electron beam pumped wide bandgap semiconductor lasers, incoherent wide bandgap semiconductor light emitting devices, and hollow cathode metal ion lasers to perform non-contact, non-invasive detection of unknown chemical analytes. These deep ultraviolet sources enable dramatic size, weight and power consumption reductions of chemical analysis instruments. In some embodiments, Raman spectroscopic detection methods and apparatus use ultra-narrow-band angle tuning filters, acousto-optic tuning filters, and temperature tuned filters to enable ultra-miniature analyzers for chemical identification. In some embodiments Raman analysis is conducted along with photoluminescence spectroscopy (i.e. fluorescence and/or phosphorescence spectroscopy) to provide high levels of sensitivity and specificity in the same instrument.
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公开(公告)号:US10895533B1
公开(公告)日:2021-01-19
申请号:US16820309
申请日:2020-03-16
Applicant: Photon Systems, Inc.
Inventor: William F. Hug , Röhit Bhartia , Ray D. Reid , Arthur L. Lane
Abstract: Naphthalene, benzene, toluene, xylene, and other volatile organic compounds VOCs have been identified as serious health hazards. Embodiments of the invention are directed to methods and apparatus for near-real-time in-situ detection and accumulated dose measurement of exposure to naphthalene vapor and other hazardous gaseous VOCs. The methods and apparatus employ excitation of fluorophors native or endogenous to compounds of interest using light sources emitting in the ultraviolet below 300 nm and measurement of native fluorescence emissions in distinct wavebands above the excitation wavelength. The apparatus of some embodiments are cell-phone-sized sensor/dosimeter “badges” to be worn by personnel potentially exposed to hazardous VOCs. The badge sensor of some embodiments provides both real time detection and data logging of exposure to naphthalene or other VOCs of interest from which both instantaneous and accumulated dose can be determined.
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公开(公告)号:US09915603B1
公开(公告)日:2018-03-13
申请号:US15432865
申请日:2017-02-14
Applicant: Photon Systems, Inc.
Inventor: William F. Hug , Ray D. Reid , Rohit Bhartia , Arthur L. Lane
CPC classification number: G01N21/33 , G01J3/10 , G01J3/36 , G01J3/44 , G01N21/64 , G01N21/645 , G01N21/65 , G01N27/44721 , G01N2021/6421 , G01N2021/6471 , G01N2201/06113 , G01N2201/0612 , G01N2201/068
Abstract: Spectroscopic chemical analysis methods and apparatus are disclosed which employ deep ultraviolet (e.g. in the 200 nm to 300 nm spectral range) electron beam pumped wide bandgap semiconductor lasers, incoherent wide bandgap semiconductor light emitting devices, and hollow cathode metal ion lasers to perform non-contact, non-invasive detection of unknown chemical analytes. These deep ultraviolet sources enable dramatic size, weight and power consumption reductions of chemical analysis instruments. In some embodiments, Raman spectroscopic detection methods and apparatus use ultra-narrow-band angle tuning filters, acousto-optic tuning filters, and temperature tuned filters to enable ultra-miniature analyzers for chemical identification. In some embodiments Raman analysis is conducted along with photoluminescence spectroscopy (i.e. fluorescence and/or phosphorescence spectroscopy) to provide high levels of sensitivity and specificity in the same instrument.
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公开(公告)号:US11262301B1
公开(公告)日:2022-03-01
申请号:US17013469
申请日:2020-09-04
Applicant: Photon Systems, Inc.
Inventor: William F. Hug , Rohit Bhartia , Ray D. Reid , Arthur L. Lane
Abstract: Naphthalene, benzene, toluene, xylene, and other volatile organic compounds VOCs have been identified as serious health hazards. Embodiments of the invention are directed to methods and apparatus for near-real-time in-situ detection and accumulated dose measurement of exposure to naphthalene vapor and other hazardous gaseous VOCs. The methods and apparatus employ excitation of fluorophors native or endogenous to compounds of interest using light sources emitting in the ultraviolet below 300 nm and measurement of native fluorescence emissions in distinct wavebands above the excitation wavelength. The apparatus of some embodiments are cell-phone-sized sensor/dosimeter “badges” to be worn by personnel potentially exposed to hazardous VOCs. The badge sensor of some embodiments provides both real time detection and data logging of exposure to naphthalene or other VOCs of interest from which both instantaneous and accumulated dose can be determined.
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公开(公告)号:US11448598B1
公开(公告)日:2022-09-20
申请号:US17374902
申请日:2021-07-13
Applicant: Photon Systems, Inc.
Inventor: Rohit Bhartia , Michael R. Reid , William F. Hug , Ray D. Reid
IPC: G01N21/64 , G01N21/33 , G01N33/569 , G01N21/3577 , G01N21/359 , G01N21/65 , G01N21/17
Abstract: Methods, apparatus, and systems provide improved identification of selected biohazard and/or biohazard signatures from complex in vivo or in vitro samples and include deep UV native fluorescence spectroscopic analysis for multiple locations of a sample wherein classification results for individual locations are combined and spatially correlated to provide a positive or negative conclusion of biohazard signature presence (e.g., for signatures for viruses, bacteria, and diseases including SARS-CoV-2 and its variants and COVID-19 and its variants). Improvements include one or more of reduced sample processing time (minutes to fractions of a minute), reduced sampling cost (dollars to fractions of a dollar), high conclusion reliability (rivaling real time RT-PCR). Some embodiments may incorporate a stage or scanning mirror system to provide movement of a sample relative to an excitation exposure location. Some embodiments may incorporate Raman or phosphorescence spectroscopic analysis as well as imaging systems.
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公开(公告)号:US10890533B1
公开(公告)日:2021-01-12
申请号:US16688894
申请日:2019-11-19
Applicant: Photon Systems, Inc.
Inventor: William F. Hug , Ray D. Reid , Rohit Bhartia , Arthur L. Lane
Abstract: Spectroscopic chemical analysis methods and apparatus are disclosed which employ deep ultraviolet (e.g. in the 200 nm to 300 nm spectral range) electron beam pumped wide bandgap semiconductor lasers, incoherent wide bandgap semiconductor light emitting devices, and hollow cathode metal ion lasers to perform non-contact, non-invasive detection of unknown chemical analytes. These deep ultraviolet sources enable dramatic size, weight and power consumption reductions of chemical analysis instruments. In some embodiments, Raman spectroscopic detection methods and apparatus use ultra-narrow-band angle tuning filters, acousto-optic tuning filters, and temperature tuned filters to enable ultra-miniature analyzers for chemical identification. In some embodiments Raman analysis is conducted along with photoluminescence spectroscopy (i.e. fluorescence and/or phosphorescence spectroscopy) to provide high levels of sensitivity and specificity in the same instrument.
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公开(公告)号:US10598596B1
公开(公告)日:2020-03-24
申请号:US16362453
申请日:2019-03-22
Applicant: Photon Systems, Inc.
Inventor: William F. Hug , Rohit Bhartia , Ray D. Reid , Arthur L. Lane
Abstract: Naphthalene, benzene, toluene, xylene, and other volatile organic compounds VOCs have been identified as serious health hazards. Embodiments of the invention are directed to methods and apparatus for near-real-time in-situ detection and accumulated dose measurement of exposure to naphthalene vapor and other hazardous gaseous VOCs. The methods and apparatus employ excitation of fluorophors native or endogenous to compounds of interest using light sources emitting in the ultraviolet below 300 nm and measurement of native fluorescence emissions in distinct wavebands above the excitation wavelength. The apparatus of some embodiments are cell-phone-sized sensor/dosimeter “badges” to be worn by personnel potentially exposed to hazardous VOCs. The badge sensor of some embodiments provides both real time detection and data logging of exposure to naphthalene or other VOCs of interest from which both instantaneous and accumulated dose can be determined.
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