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    Dynamic bioactive bone graft material having an engineered porosity
    1.
    发明授权
    Dynamic bioactive bone graft material having an engineered porosity 有权

    公开(公告)号：US11338061B2

    公开(公告)日：2022-05-24

    申请号：US16695997

    申请日：2019-11-26

    申请人： Prosidyan, Inc.

    发明人： Charanpreet S. Bagga ,  Hyun W. Bae ,  Thomas E. Day

    IPC分类号： A61F2/28 ,  A61L27/10 ,  A61L27/12 ,  A61L27/54 ,  A61L27/56 ,  A61L27/58 ,  A61L27/42

    摘要： The present disclosure relates to a dynamic bioactive bone graft material having an engineered porosity. In one embodiment, a bone graft material is provided having bioactive glass fibers arranged in a porous matrix that is moldable into a desired shape for implantation. The material can be substantially without additives and can include at least one nanofiber. The porous matrix may include a combination of one or more pore sizes including nanopores, macropores, mesopores, and micropores. In another embodiment, a bone graft implant is provided having a matrix comprising a plurality of overlapping and interlocking bioactive glass fibers, and having a distributed porosity based on a range of pores provided in the bioactive glass fibers. The distributed porosity can comprise a combination of macropores, mesopores, and micropores, and the matrix can be formable into a desired shape for implantation into a patient.

    BIOACTIVE IMPLANTABLE DEVICES, AND COMPOSITE BIOMATERIALS AND METHODS FOR MAKING THE SAME
    3.
    发明申请
    BIOACTIVE IMPLANTABLE DEVICES, AND COMPOSITE BIOMATERIALS AND METHODS FOR MAKING THE SAME 有权

    公开(公告)号：US20210260242A1

    公开(公告)日：2021-08-26

    申请号：US17182920

    申请日：2021-02-23

    申请人： PROSIDYAN, INC.

    发明人： Charanpreet S. Bagga ,  Robert T. Warren ,  Hyun W. Bae

    IPC分类号： A61L27/10 ,  A61L27/44 ,  A61L27/58 ,  A61L27/56 ,  A61L27/54

    摘要： Implantable medical devices, composite bioactive polymeric biomaterials for forming such devices, and methods for manufacturing these biomaterials and devices are provided. The implantable medical devices are engineered, at least in part, from a composite material comprising a polymer component and a bioactive component incorporated therein to provide bioactivity to the polymeric component for the improved treatment of bone or other purposes. The implantable device may comprise a main body formed of a polymeric framework, and a bioactive glass additive incorporated into the rigid polymeric framework. The implantable device may also comprise a main body and a bioactive component that includes a polyarylretherketone (PAEK) polymer component and a bioactive additive component. The bioactive additive component is incorporated substantially throughout the polymer component to further enhance cellular activity to promote bone fusion and/or regeneration.

    DYNAMIC BIOACTIVE BONE GRAFT MATERIAL HAVING AN ENGINEERED POROSITY
    7.
    发明申请
    DYNAMIC BIOACTIVE BONE GRAFT MATERIAL HAVING AN ENGINEERED POROSITY 审中-公开

    公开(公告)号：US20200093963A1

    公开(公告)日：2020-03-26

    申请号：US16695997

    申请日：2019-11-26

    申请人： Prosidyan, Inc.

    发明人： Charanpreet S. Bagga ,  Hyun W. Bae ,  Thomas E. Day

    IPC分类号： A61L27/42

    摘要： The present disclosure relates to a dynamic bioactive bone graft material having an engineered porosity. In one embodiment, a bone graft material is provided having bioactive glass fibers arranged in a porous matrix that is moldable into a desired shape for implantation. The material can be substantially without additives and can include at least one nanofiber. The porous matrix may include a combination of one or more pore sizes including nanopores, macropores, mesopores, and micropores. In another embodiment, a bone graft implant is provided having a matrix comprising a plurality of overlapping and interlocking bioactive glass fibers, and having a distributed porosity based on a range of pores provided in the bioactive glass fibers. The distributed porosity can comprise a combination of macropores, mesopores, and micropores, and the matrix can be formable into a desired shape for implantation into a patient.