公开(公告)号：US20180326077A1

公开(公告)日：2018-11-15

申请号：US15310416

申请日：2015-05-12

Applicant: Purdue Research Foundation

Inventor： Alyssa Panitch ,  Rebecca Scott ,  Kinam Park ,  James Wodicka

IPC: A61K47/42 ,  A61K47/61 ,  C08B37/02 ,  C07K14/47 ,  A61K47/54 ,  C08B37/00 ,  C08B37/08 ,  A61P9/14 ,  A61P9/10 ,  A61P29/00 ,  C07D487/04

CPC classification number: A61K47/42 ,  A61K47/545 ,  A61K47/61 ,  A61P9/10 ,  A61P9/14 ,  A61P29/00 ,  C07D487/04 ,  C07K14/4725 ,  C08B37/0021 ,  C08B37/0069 ,  C08B37/0072

Abstract: The invention relates to peptide conjugates that can bind to endothelial cells, and that are useful for reducing the incidence and severity of endothelial dysfunction in mammals.

公开(公告)号：US10828370B2

公开(公告)日：2020-11-10

申请号：US15310416

申请日：2015-05-12

Applicant: Purdue Research Foundation

Inventor： Alyssa Panitch ,  Rebecca Scott ,  Kinam Park ,  James Wodicka

IPC: A61K38/08 ,  A61K47/42 ,  C07D487/04 ,  C08B37/02 ,  C08B37/00 ,  C08B37/08 ,  A61K47/61 ,  A61K47/54 ,  A61P9/10 ,  A61P29/00 ,  A61P9/14 ,  C07K14/47

Abstract: The invention relates to peptide conjugates that can bind to endothelial cells, and that are useful for reducing the incidence and severity of endothelial dysfunction in mammals.