公开(公告)号：US09960028B2

公开(公告)日：2018-05-01

申请号：US15318846

申请日：2015-06-16

Applicant: Purdue Research Foundation

Inventor： Zheng Ouyang ,  Xiao Wang ,  Xiaoyu Zhou

IPC: H01J37/04 ,  H01J49/04 ,  H01J49/24 ,  H01J49/00

CPC classification number: H01J49/04 ,  H01J49/0013 ,  H01J49/0468 ,  H01J49/24

Abstract: The invention generally relates to systems and methods for analyzing a sample from a surface. In certain aspects, the invention provides systems that include a sample introduction member that has an inlet, an outlet, and an opening along a wall of the sample introduction member. The sample introduction member may be configured such that the opening couples with a surface that includes a sample in a manner in which molecules of the sample enter the sample introduction member via the opening and exit the sample introduction member via the outlet. A mass spectrometer is configured to receive the molecules of the sample.

公开(公告)号：US20170140912A1

公开(公告)日：2017-05-18

申请号：US15318846

申请日：2015-06-16

Applicant: Purdue Research Foundation

Inventor： Zheng Ouyang ,  Xiao Wang ,  Xiaoyu Zhou

IPC: H01J49/04 ,  H01J49/00 ,  H01J49/24

CPC classification number: H01J49/04 ,  H01J49/0013 ,  H01J49/0468 ,  H01J49/24

Abstract: The invention generally relates to systems and methods for analyzing a sample from a surface. In certain aspects, the invention provides systems that include a sample introduction member that has an inlet, an outlet, and an opening along a wall of the sample introduction member. The sample introduction member may be configured such that the opening couples with a surface that includes a sample in a manner in which molecules of the sample enter the sample introduction member via the opening and exit the sample introduction member via the outlet. A mass spectrometer is configured to receive the molecules of the sample.

公开(公告)号：US20160181077A1

公开(公告)日：2016-06-23

申请号：US14909269

申请日：2014-08-06

Applicant: Purdue Research Foundation

Inventor： Zheng Ouyang ,  Linfan Li ,  Xiaoyu Zhou

IPC: H01J49/00 ,  H01J49/04

CPC classification number: H01J49/0031 ,  H01J49/0013 ,  H01J49/004 ,  H01J49/0422

Abstract: The invention generally relates to sample analysis with a miniature mass spectrometer. In certain embodiments, the invention provides methods that involve generating ions of a first analyte and ions of a second analyte. Those ions are transferred through a discontinuous sample introduction interface into a first ion trap of a mass spectrometer in a manner in which the discontinuous sample introduction interface remains open during the transferring. The discontinuous sample introduction interface is closed and the ions are sequentially transferred to a second ion trap of the mass spectrometer where they are sequentially analyzed.

Abstract translation: 本发明一般涉及使用微型质谱仪的样品分析。 在某些实施方案中，本发明提供涉及产生第一分析物的离子和第二分析物的离子的方法。 这些离子以不连续的样品引入界面在转移期间保持打开的方式通过不连续的样品引入界面转移到质谱仪的第一离子阱中。 关闭不连续的样品引入界面，并将离子顺序地转移到质谱仪的第二离子阱上，在其中依次分析它们。

公开(公告)号：US10930481B2

公开(公告)日：2021-02-23

申请号：US14909269

申请日：2014-08-06

Applicant: Purdue Research Foundation

Inventor： Zheng Ouyang ,  Linfan Li ,  Xiaoyu Zhou

IPC: H01J49/00 ,  H01J49/04

Abstract: The invention generally relates to sample analysis with a miniature mass spectrometer. In certain embodiments, the invention provides methods that involve generating ions of a first analyte and ions of a second analyte. Those ions are transferred through a discontinuous sample introduction interface into a first ion trap of a mass spectrometer in a manner in which the discontinuous sample introduction interface remains open during the transferring. The discontinuous sample introduction interface is closed and the ions are sequentially transferred to a second ion trap of the mass spectrometer where they are sequentially analyzed.

公开(公告)号：US20210166927A1

公开(公告)日：2021-06-03

申请号：US17153156

申请日：2021-01-20

Applicant: Purdue Research Foundation

Inventor： Zheng Ouyang ,  Linfan Li ,  Xiaoyu Zhou

IPC: H01J49/00 ,  H01J49/04

Abstract: The invention generally relates to sample analysis with a miniature mass spectrometer. In certain embodiments, the invention provides methods that involve generating ions of a first analyte and ions of a second analyte. Those ions are transferred through a discontinuous sample introduction interface into a first ion trap of a mass spectrometer in a manner in which the discontinuous sample introduction interface remains open during the transferring. The discontinuous sample introduction interface is closed and the ions are sequentially transferred to a second ion trap of the mass spectrometer where they are sequentially analyzed.