摘要:
A compound of formula the following formula: (I). In this formula, moieties A, B, X, R1, R2, and R3 are defined herein. Also disclosed are a nanocomplex that is formed of such a compound and a pharmaceutical agent, and a nanocomplex that is formed of a protein and a bioreducible compound.
摘要:
A compound of formula the following formula: (I). In this formula, moieties A, B, X, R1, R2, and R3 are defined herein. Also disclosed are a nanocomplex that is formed of such a compound and a pharmaceutical agent, and a nanocomplex that is formed of a protein and a bioreducible compound.
摘要:
A nanocomplex, of particle size 50 nm to 1000 nm, containing saporin and a lipid-like compound, in which saporin binds to the lipid-like compound via non-covalent interaction or covalent bonding. The lipid-like compound has a hydrophilic moiety, a hydrophobic moiety, and a linker joining the hydrophilic moiety and the hydrophobic moiety. The hydrophilic moiety is optionally charged and the hydrophobic moiety has 8 to 24 carbon atoms. Also disclosed is a pharmaceutical composition containing such a nanocomplex and a pharmaceutically acceptable carrier. The nanocomplex is useful in treating diseases, such as cancer.
摘要:
The invention discloses a wool raw wool washing device for chemical fiber production, which includes a washing machine. The washing machine is provided with a working cavity. A front end wall of the working cavity is provided with a storage cavity with an upward opening. The wool raw wool is installed in the washing machine. Two dispersing mechanisms are symmetrically arranged in the working cavity in the storage cavity, and the dispersing mechanism includes a connecting shaft rotatably connected to the rear wall of the working cavity. A rotating wheel is fixed at the front end of the connecting shaft. The connecting shaft is provided with a collar that can slide back and forth, and the rotating wheel is provided with a slidable dispersing rod. The rotation of the connecting shaft can drive the rotating wheel to rotate, and the device can disperse the raw wool in the lump. After washing into small balls, it has a high washing efficiency, and by dispersing into small balls, it helps to discharge the stones and branches in the wool, and has a good washing effect. The overall mechanical linkage of the device is relatively good, High, more energy efficient.
摘要:
The present invention is directed to substituted triazolo bicyclic compounds of formula I which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 2 (PDE2). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis, Parkinson's disease, Parkinson's disease dementia (PDD), or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.
摘要:
The present disclosure provides a power semiconductor switch series circuit. The power semiconductor switch series circuit includes a plurality of series modules and a system control module. Each series module has a power semiconductor switch; a drive module for driving each power semiconductor switch to be turned on or turned off; a short-circuit detection unit for outputting at least one detection signal; an equalizer circuit; a comparison module for comparing the detection signal with a predetermined threshold, and outputting a short-circuit signal when the detection signal exceeds the predetermined threshold; and a soft turn-off module for receiving the short-circuit signal and outputting a second control signal. The system control module receives the short-circuit signal and outputs a first control signal.
摘要:
This invention relates to novel indane acetic acid derivatives which are useful in the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic diseases. The invention also relates to intermediates useful in preparation of indane acetic derivatives and to methods of preparation.
摘要:
The present invention is directed to an electrophoretic fluid comprising uncharged or lightly charged neutral buoyancy particles. The resulting fluid can improve not only image stability but also contrast ratio of a display device, without significantly affecting the switching speed. The present invention is also directed to an electrophoretic display comprising display cells filled with the electrophoretic fluid.
摘要:
The present invention relates to a printed circuit board. In one embodiment, a printed circuit board includes a dielectric layer and a conductive trace formed on the dielectric layer. The conductive layer includes a first conductive portion, a connecting portion and a second conductive portion. The connecting portion includes a first end and a second end. The first end is connected to the first conductive portion; the second end is connected to the second conductive portion. A width of the connecting portion gradually decreases from the first end to the second end. Reflection and cross talk of signals transmitted in the presented printed circuit board can be reduced.