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17 条记录 (耗时 0.017 秒)

    Interactive test device and apparatus with timing mechanism
    2.
    发明授权
    Interactive test device and apparatus with timing mechanism 有权

    公开(公告)号：US11061020B2

    公开(公告)日：2021-07-13

    申请号：US13783065

    申请日：2013-03-01

    申请人： Quidel Corporation

    发明人： Rhys de Callier ,  Richard L. Egan ,  William J. Ferenczy ,  Michael Jon Hale

    IPC分类号： G01N33/53 ,  G01N33/558 ,  G01N33/58

    摘要： A system comprised of an apparatus and a test device is described. The test device and the apparatus are designed to interact to determine the presence or absence of an analyte of interest in a sample placed on the test device. The test device and apparatus interact to provide a timer feature for determining a test device specific adjustable cut-off value that is used to ascertain whether signal from a test line in the device corresponds to a positive or negative results, irrespective of the time elapsed since placement of sample on the test device. The adjustable cut-off value renders the system relatively insensitive to incubation time of the test device, where if the incubation time is shorter or longer than needed for accuracy of a test result, the analyzer will report an invalid result, thus preventing the reporting of an incorrect (false negative or false positive) result.

    INTERACTIVE TEST DEVICE AND APPARATUS WITH TIMING MECHANISM
    7.
    发明申请
    INTERACTIVE TEST DEVICE AND APPARATUS WITH TIMING MECHANISM 有权

    公开(公告)号：US20210293793A1

    公开(公告)日：2021-09-23

    申请号：US17343490

    申请日：2021-06-09

    申请人： Quidel Corporation

    发明人： Rhys L. de Callier ,  Richard L. Egan ,  William J. Ferenczy ,  Michael Jon Hale

    IPC分类号： G01N33/53 ,  G01N33/558 ,  G01N33/58

    摘要： A system comprised of an apparatus and a test device is described. The test device and the apparatus are designed to interact to determine the presence or absence of an analyte of interest in a sample placed on the test device. The test device and apparatus interact to provide a timer feature for determining a test device specific adjustable cut-off value that is used to ascertain whether signal from a test line in the device corresponds to a positive or negative results, irrespective of the time elapsed since placement of sample on the test device. The adjustable cut-off value renders the system relatively insensitive to incubation time of the test device, where if the incubation time is shorter or longer than needed for accuracy of a test result, the analyzer will report an invalid result, thus preventing the reporting of an incorrect (false negative or false positive) result.

    Processing reagent and use thereof in assays for detection of analytes associated with a binding protein
    8.
    发明授权
    Processing reagent and use thereof in assays for detection of analytes associated with a binding protein 有权

    公开(公告)号：US10338084B2

    公开(公告)日：2019-07-02

    申请号：US15482332

    申请日：2017-04-07

    申请人： Quidel Corporation

    发明人： Richard L. Egan ,  Judson McFarland ,  Mark Renshaw

    IPC分类号： G01N33/53 ,  G01N33/82

    摘要： Methods for preparing a sample for detection of an analyte of interest that is bound in vivo to a protein are provided. The method comprises providing a processing reagent comprising metaperiodate and contacting a sample suspected of comprising an analyte of interest associated with a protein with the processing reagent to form a mixture. The analyte of interest, if present in the sample (or mixture), is separated from its associated protein for detection of the analyte of interest. In one embodiment, the method is applied to samples for the detection of levels of vitamin D circulating in the blood. Samples are processed using the reagent disclosed herein to separate the analyte of interest, vitamin D or a metabolite thereof, from the vitamin D binding protein and/or albumin, for detection of the analyte separated from its binding protein(s).