公开(公告)号：US20100228135A1

公开(公告)日：2010-09-09

申请号：US12757158

申请日：2010-04-09

申请人： Randal C. Schulhauser ,  Matthew C. Bond ,  Michael R. Kane

发明人： Randal C. Schulhauser ,  Matthew C. Bond ,  Michael R. Kane

IPC分类号： A61B5/026

CPC分类号： A61B5/0261 ,  A61B5/0031 ,  A61B5/0084 ,  A61B5/076 ,  A61B5/413

摘要： An injectable wireless perfusion sensor provides data to an external device regarding the perfusion of the targeted tissue. The sensor permits a caregiver to monitor cardiovascular performance in specific areas such as the extremities. The sensor will identify whether vascular constriction or obstruction is present and to what extent. Further, once such a condition is treated, the sensor will monitor the effectiveness of that treatment.

摘要翻译： 可注射无线灌注传感器向外部装置提供关于目标组织灌注的数据。 传感器允许护理人员监测特定区域（如四肢）的心血管功能。 传感器将识别是否存在血管收缩或阻塞以及在多大程度上。 此外，一旦处理这样的状况，传感器将监测该治疗的有效性。

公开(公告)号：US06236882B1

公开(公告)日：2001-05-22

申请号：US09353167

申请日：1999-07-14

申请人： Brian B. Lee ,  Michael R. Kane ,  Gregg Turi

发明人： Brian B. Lee ,  Michael R. Kane ,  Gregg Turi

IPC分类号： A61B50402

CPC分类号： A61B5/0402 ,  A61B5/0432 ,  A61B5/0456 ,  A61B5/7203 ,  A61B5/7232

摘要： An implantable medical device which preferably has a segmented looping memory for storing triggered physiologic events also has autotriggers to record the ECGs and any other relevant physiologic signals occurring during triggering events. The problem is that in the far field R-wave sensing is difficult because of noise. Denial and extensible accommodation periods are introduced into the R-wave sensing registration for triggering data storage. If the event is sensed during an accommodation period the sense will not add an R-wave sense to the trigger's count of R-waves. It may cause resetting of the trigger count in some circumstnaces. Typical triggering events may include arrhythmia's and syncopal events. Preferably the device can function without a microprocessor. An outside device or other patient activated manual trigger may be included. Auto triggers and manually set triggers may be of different sizes. Electrode spacing can be critical. Additional sensors may be provided to the device. Preferred communications with the device is through telemetry such as is used for pacemakers and other implanted devices.

摘要翻译： 优选地具有用于存储触发的生理事件的分段循环存储器的可植入医疗装置还具有记录ECG的自动触发器以及在触发事件期间发生的任何其它相关生理信号。 问题在于，在远场R波传感由于噪声困难。 拒绝和可延伸的住宿期被引入到R波感测注册中以触发数据存储。 如果在住宿期间感测到事件，感觉不会在触发器的R波数量上增加R波感。 在某些情况下可能会导致触发计数的重置。 典型的触发事件可能包括心律失常和晕厥事件。 优选地，该装置可以在没有微处理器的情况下工作。 可以包括外部设备或其他患者激活的手动触发器。 自动触发器和手动设置触发器可能具有不同的大小。 电极间距可能很重要。 可以向设备提供附加的传感器。 与设备的首选通信是通过诸如用于起搏器和其他植入设备的遥测。

公开(公告)号：US06985776B2

公开(公告)日：2006-01-10

申请号：US10423113

申请日：2003-04-25

申请人： Michael R. Kane ,  George K. Wong

发明人： Michael R. Kane ,  George K. Wong

IPC分类号： A61N1/05

CPC分类号： A61N1/056 ,  A61N2001/0578 ,  A61N2001/0585

摘要： A system and method of positioning an implantable medical device lead within a patient that includes introducing a distal tip of a first elongated member along a first location within the patient through a first introducing path, and introducing a distal tip of a second elongated member within the first location through a second introducing path. The distal tip of the first elongated member is engaged with the distal tip of the second elongated member at the first location, and, upon engagement, the distal tip of the first elongated member is advanced to a second location via the second elongated member as the second elongation member is advanced to the second location.

摘要翻译： 一种将可植入医疗装置引线定位在患者体内的系统和方法，其包括通过第一引入路径沿着患者体内的第一位置引入第一细长构件的远侧末端，以及将第二细长构件的远侧末端引入 第一个位置通过第二个引入路径。 第一细长构件的远侧末端在第一位置处与第二细长构件的远侧末端接合，并且在接合时，第一细长构件的远侧末端经由第二细长构件前进到第二位置，如 第二伸长构件前进到第二位置。

公开(公告)号：US07027858B2

公开(公告)日：2006-04-11

申请号：US10238140

申请日：2002-09-11

申请人： Jian Cao ,  Lee B. Brian ,  Michael R. Kane ,  Spencer R. Hurd

发明人： Jian Cao ,  Lee B. Brian ,  Michael R. Kane ,  Spencer R. Hurd

IPC分类号： A61B5/04

CPC分类号： A61B5/0468 ,  A61B5/04325 ,  A61B5/0456 ,  A61B5/7203 ,  A61B5/7221

摘要： The present invention uses a R-wave sensing algorithm that uniquely combines an automatic threshold adjustment method with a new noise rejection technique. This algorithm has significant advantages in avoiding the sensing of T-waves, P-waves, and noise/artifacts. Detecting the presence of noise bursts uses features that determine if an R-R interval adjacent to or within the noise signal is valid. Circuitry that discriminates noise signals from R-waves can use any one of several features including, but not limited to, the following: detection events occurring so close together that they are outside normal physiologic heart rates; frequency content that is wider than that of QRS complexes; amplitudes that are different than the adjacent or encompassing R-waves; and amplitudes that display greater than normal variability. The present invention employs multiple discrete thresholds optionally with different decay constants, alone or in combination with one or more substantially constant magnitude sensing threshold.

摘要翻译： 本发明使用独特地组合自动阈值调整方法和新的噪声抑制技术的R波感测算法。 该算法在避免T波，P波和噪声/伪影的检测方面具有显着的优势。 检测噪声突发的存在使用确定与噪声信号相邻或内部的R-R间隔是否有效的特征。 鉴别来自R波的噪声信号的电路可以使用几个特征中的任何一个，包括但不限于以下：检测事件如此紧密地发生，使得它们在正常生理心率之外; 频率含量比QRS复合物宽; 与相邻或包围的R波不同的振幅; 和显示大于正常变异性的振幅。 本发明单独或与一个或多个基本上恒定的幅度感测阈值组合使用多个离散阈值，其可选地具有不同的衰减常数。

公开(公告)号：US06496715B1

公开(公告)日：2002-12-17

申请号：US09718689

申请日：2000-11-22

申请人： Brian B. Lee ,  Michael R. Kane ,  Eric J. Panken ,  James D. Reinke

发明人： Brian B. Lee ,  Michael R. Kane ,  Eric J. Panken ,  James D. Reinke

IPC分类号： A61B504

CPC分类号： A61N1/375

摘要： A system and method for determining the optimal positioning of an implantable system for sensing physiologic signals within a body. According to a one embodiment of the system, electrodes are positioned on an external surface of a body, and an ECG monitoring device is used to measure cardiac signals between various pairs of the electrodes. One or more of the electrodes may be re-positioned until an electrode pair position and orientation is located that provides a maximum signal reading. This position and orientation may then be used as the position and orientation in which to implant a corresponding device.

摘要翻译： 一种用于确定用于感测身体内的生理信号的可植入系统的最佳定位的系统和方法。 根据系统的一个实施例，电极定位在身体的外表面上，并且使用ECG监测装置来测量各对电极之间的心脏信号。 一个或多个电极可以被重新定位，直到位于提供最大信号读数的电极对位置和取向。 然后可以将该位置和取向用作植入相应装置的位置和取向。

公开(公告)号：US07016721B2

公开(公告)日：2006-03-21

申请号：US09975621

申请日：2001-10-10

申请人： Brian B. Lee ,  Michael R. Kane

发明人： Brian B. Lee ,  Michael R. Kane

IPC分类号： A61B5/0432

CPC分类号： A61B5/0006 ,  A61B5/0031 ,  A61B5/0456 ,  A61B5/7203 ,  A61B5/7232 ,  A61B5/7285 ,  A61N1/3718

摘要： Triggers and noise should be available as information in recorded electrograms in memories of implantable medical devices. Particularly where the recording of electrogram data is done in the far field, there will be considerable noise and the interpretation of ECG's reproduced from such recorded data will benefit from the storing of information regarding contemporaneous noise. By storing contemporaneous trigger data and noise data directly in the ECG data, recordings of the ECG data become more useful for physician use when played back through an external display system with minimal loss of ECG data, since out of range values are employed for the noise and trigger information and this non-ECG data is limited in size to no longer than individual point values of the ECG signal.

公开(公告)号：US06611761B2

公开(公告)日：2003-08-26

申请号：US09837794

申请日：2001-04-18

申请人： Bikash K. Sinha ,  Robert Burridge ,  Michael R. Kane

发明人： Bikash K. Sinha ,  Robert Burridge ,  Michael R. Kane

IPC分类号： G01V140

CPC分类号： G01V1/48 ,  G01V1/50

摘要： A method for determining a radial profile of sonic shear velocity of formations surrounding a fluid-containing borehole, including: suspending a logging device in the borehole; transmitting sonic energy from the logging device to establish flexural waves in the formation; receiving sonic energy from the flexural waves and producing, from the received sonic energy, measurement signals at a number of frequencies; determining, at each frequency, the flexural wave velocity in the formation; deriving sonic compressional and shear velocities of the substantially undisturbed formation; deriving sonic compressional velocity of the borehole fluid; and determining the radial profile of sonic shear velocity from the derived compressional and shear velocities of the substantially undisturbed formation, the derived compressional velocity of the borehole fluid, and the flexural wave velocities.

公开(公告)号：US06347245B1

公开(公告)日：2002-02-12

申请号：US09353277

申请日：1999-07-14

申请人： Brian B. Lee ,  Michael R. Kane

发明人： Brian B. Lee ,  Michael R. Kane

IPC分类号： A61B50432

CPC分类号： A61B5/0006 ,  A61B5/0031 ,  A61B5/0456 ,  A61B5/7203 ,  A61B5/7232 ,  A61B5/7285 ,  A61N1/3718

摘要： A system for recording trigger events and noise in conjunction with the recording of physiological signals is provided for use in an implantable medical device. In one embodiment, recorded trigger and noise data is provided for display to a physician along with reconstructed ECG data to facilitate interpretation of the ECG signal. In one embodiment, digitized ECG samples that are outside of a predetermined range are discarded during the sampling process so that one or more ranges of encoded values are available for use in encoding noise and trigger information. This non-physiologic data may be limited in size to individual point values of the ECG signal.

摘要翻译： 提供了用于记录触发事件和噪声以及生理信号记录的系统，用于可植入医疗装置。 在一个实施例中，记录的触发和噪声数据被提供用于与重建的ECG数据一起显示给医师以便于ECG信号的解读。 在一个实施例中，在采样过程中丢弃在预定范围之外的数字化ECG样本，使得编码值的一个或多个范围可用于编码噪声和触发信息。 该非生理数据的大小可能受到ECG信号的各个点值的限制。