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公开(公告)号：US07081354B2
公开(公告)日：2006-07-25
申请号：US10237708
申请日：2002-09-10
CPC分类号： B65B69/00 , A61K38/21 , A61K38/38 , A61K47/642 , A61K47/643 , C07K14/575 , C07K14/755 , C07K14/76 , C07K14/765 , C07K2319/00 , C07K2319/02 , C07K2319/31 , C07K2319/33 , C12N9/6456 , A61K2300/00
摘要： Biologically active polypeptides comprising a therapeutically active polypeptide fused to human serum albumin or a variant thereof, methods for the preparation thereof, nucleotide sequences encoding such fusion polypeptides, expression cassettes comprising such nucleotide sequences, self-replicating plasmids containing such expression cassettes, and pharmaceutical compositions containing said fusion polypeptides.
摘要翻译： 包含与人血清白蛋白或其变体融合的治疗活性多肽的生物活性多肽，其制备方法，编码这种融合多肽的核苷酸序列，包含该核苷酸序列的表达盒，含有该表达盒的自体复制质粒和药物组合物 含有所述融合多肽。
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公开(公告)号：US07056701B2
公开(公告)日：2006-06-06
申请号：US10237624
申请日：2002-09-10
CPC分类号： B65B69/00 , A61K38/21 , A61K38/38 , A61K47/642 , A61K47/643 , C07K14/575 , C07K14/755 , C07K14/76 , C07K14/765 , C07K2319/00 , C07K2319/02 , C07K2319/31 , C07K2319/33 , C12N9/6456 , A61K2300/00
摘要： Biologically active polypeptides comprising a therapeutically active polypeptide fused to human serum albumin or a variant thereof, methods for the preparation thereof, nucleotide sequences encoding such fusion polypeptides, expression cassettes comprising such nucleotide sequences, self-replicating plasmids containing such expression cassettes, and pharmaceutical compositions containing said fusion polypeptides.
摘要翻译： 包含与人血清白蛋白或其变体融合的治疗活性多肽的生物活性多肽，其制备方法，编码这种融合多肽的核苷酸序列，包含该核苷酸序列的表达盒，含有该表达盒的自体复制质粒和药物组合物 含有所述融合多肽。
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公开(公告)号：US07435410B2
公开(公告)日：2008-10-14
申请号：US11146077
申请日：2005-06-07
CPC分类号： B65B69/00 , A61K38/21 , A61K38/38 , A61K47/642 , A61K47/643 , C07K14/575 , C07K14/755 , C07K14/76 , C07K14/765 , C07K2319/00 , C07K2319/02 , C07K2319/31 , C07K2319/33 , C12N9/6456 , A61K2300/00
摘要： Biologically active polypeptides comprising a therapeutically active polypeptide fused to human serum albumin or a variant thereof, methods for the preparation thereof, nucleotide sequences encoding such fusion polypeptides, expression cassettes comprising such nucleotide sequences, self-replicating plasmids containing such expression cassettes, and pharmaceutical compositions containing said fusion polypeptides.
摘要翻译： 包含与人血清白蛋白或其变体融合的治疗活性多肽的生物活性多肽，其制备方法，编码这种融合多肽的核苷酸序列，包含该核苷酸序列的表达盒，含有该表达盒的自体复制质粒和药物组合物 含有所述融合多肽。
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公开(公告)号：US07094577B2
公开(公告)日：2006-08-22
申请号：US10237871
申请日：2002-09-10
CPC分类号： B65B69/00 , A61K38/21 , A61K38/38 , A61K47/642 , A61K47/643 , C07K14/575 , C07K14/755 , C07K14/76 , C07K14/765 , C07K2319/00 , C07K2319/02 , C07K2319/31 , C07K2319/33 , C12N9/6456 , A61K2300/00
摘要： Biologically active polypeptides comprising a therapeutically active polypeptide fused to human serum albumin or a variant thereof, methods for the preparation thereof, nucleotide sequences encoding such fusion polypeptides, expression cassettes comprising such nucleotide sequences, self-replicating plasmids containing such expression cassettes, and pharmaceutical compositions containing said fusion polypeptides.
摘要翻译： 包含与人血清白蛋白或其变体融合的治疗活性多肽的生物活性多肽，其制备方法，编码这种融合多肽的核苷酸序列，包含该核苷酸序列的表达盒，含有该表达盒的自体复制质粒和药物组合物 含有所述融合多肽。
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公开(公告)号：US07041478B2
公开(公告)日：2006-05-09
申请号：US10237667
申请日：2002-09-10
CPC分类号： B65B69/00 , A61K38/21 , A61K38/38 , A61K47/642 , A61K47/643 , C07K14/575 , C07K14/755 , C07K14/76 , C07K14/765 , C07K2319/00 , C07K2319/02 , C07K2319/31 , C07K2319/33 , C12N9/6456 , A61K2300/00
摘要： Biologically active polypeptides comprising a therapeutically active polypeptide fused to human serum albumin or a variant thereof, methods for the preparation thereof, nucleotide sequences encoding such fusion polypeptides, expression cassettes comprising such nucleotide sequences, self-replicating plasmids containing such expression cassettes, and pharmaceutical compositions containing said fusion polypeptides.
摘要翻译： 包含与人血清白蛋白或其变体融合的治疗活性多肽的生物活性多肽，其制备方法，编码这种融合多肽的核苷酸序列，包含该核苷酸序列的表达盒，含有该表达盒的自体复制质粒和药物组合物 含有所述融合多肽。
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6.发明授权Erythropoietin and albumin fusion protein, nucleic acids, and methods thereof 失效红细胞生成素和白蛋白融合蛋白，核酸及其方法公开(公告)号：US06987006B2
公开(公告)日：2006-01-17
申请号：US10702636
申请日：2003-11-07
CPC分类号： B65B69/00 , A61K38/21 , A61K38/38 , A61K47/642 , A61K47/643 , C07K14/575 , C07K14/755 , C07K14/76 , C07K14/765 , C07K2319/00 , C07K2319/02 , C07K2319/31 , C07K2319/33 , C12N9/6456 , A61K2300/00
摘要： Biologically active polypeptides comprising a therapeutically active polypeptide fused to human serum albumin or a variant thereof, methods for the preparation thereof, nucleotide sequences encoding such fusion polypeptides, expression cassettes comprising such nucleotide sequences, self-replicating plasmids containing such expression cassettes, and pharmaceutical compositions containing said fusion polypeptides.
摘要翻译： 包含与人血清白蛋白或其变体融合的治疗活性多肽的生物活性多肽，其制备方法，编码这种融合多肽的核苷酸序列，包含该核苷酸序列的表达盒，含有该表达盒的自体复制质粒和药物组合物 含有所述融合多肽。
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7.发明授权Fusion polypeptides of human serum albumin and a therapeutically active polypeptide 失效人血清白蛋白的融合多肽和治疗活性多肽公开(公告)号：US06686179B2
公开(公告)日：2004-02-03
申请号：US09984186
申请日：2001-10-29
IPC分类号： C12P2102
CPC分类号： B65B69/00 , A61K38/21 , A61K38/38 , A61K47/642 , A61K47/643 , C07K14/575 , C07K14/755 , C07K14/76 , C07K14/765 , C07K2319/00 , C07K2319/02 , C07K2319/31 , C07K2319/33 , C12N9/6456 , A61K2300/00
摘要： Biologically active polypeptides comprising a therapeutically active polypeptide fused to human serum albumin or a variant thereof, methods for the preparation thereof, nucleotide sequences encoding such fusion polypeptides, expression cassettes comprising such nucleotide sequences, self-replicating plasmids containing such expression cassettes, and pharmaceutical compositions containing said fusion polypeptides.
摘要翻译： 包含与人血清白蛋白或其变体融合的治疗活性多肽的生物活性多肽，其制备方法，编码这种融合多肽的核苷酸序列，包含该核苷酸序列的表达盒，含有该表达盒的自体复制质粒和药物组合物 含有所述融合多肽。
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8.发明授权Fusion polypeptides of human serum albumin and a therapeutically active polypeptide 失效人血清白蛋白的融合多肽和治疗活性多肽公开(公告)号：US07410779B2
公开(公告)日：2008-08-12
申请号：US11330353
申请日：2006-01-12
CPC分类号： B65B69/00 , A61K38/21 , A61K38/38 , A61K47/642 , A61K47/643 , C07K14/575 , C07K14/755 , C07K14/76 , C07K14/765 , C07K2319/00 , C07K2319/02 , C07K2319/31 , C07K2319/33 , C12N9/6456 , A61K2300/00
摘要： The invention includes biologically active polypeptides comprising a therapeutically active polypeptide fused to human serum albumin or a variant of human serum albumin, methods for the preparation of such fusion polypeptides, nucleotide sequences encoding such fusion polypeptides, expression cassettes comprising such nucleotide sequences, self-replicating plasmids containing such expression cassettes, and pharmaceutical compositions containing such fusion polypeptides.
摘要翻译： 本发明包括生物活性多肽，其包含与人血清白蛋白或人血清白蛋白变体融合的治疗活性多肽，制备这种融合多肽的方法，编码这种融合多肽的核苷酸序列，包含该核苷酸序列的表达盒，自我复制 含有这种表达盒的质粒和含有这种融合多肽的药物组合物。
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公开(公告)号：US06989365B2
公开(公告)日：2006-01-24
申请号：US10702536
申请日：2003-11-07
CPC分类号： B65B69/00 , A61K38/21 , A61K38/38 , A61K47/642 , A61K47/643 , C07K14/575 , C07K14/755 , C07K14/76 , C07K14/765 , C07K2319/00 , C07K2319/02 , C07K2319/31 , C07K2319/33 , C12N9/6456 , A61K2300/00
摘要： Biologically active polypeptides comprising a therapeutically active polypeptide fused to human serum albumin or a variant thereof, methods for the preparation thereof, nucleotide sequences encoding such fusion polypeptides, expression cassettes comprising such nucleotide sequences, self-replicating plasmids containing such expression cassettes, and pharmaceutical compositions containing said fusion polypeptides.
摘要翻译： 包含与人血清白蛋白或其变体融合的治疗活性多肽的生物活性多肽，其制备方法，编码这种融合多肽的核苷酸序列，包含该核苷酸序列的表达盒，含有该表达盒的自体复制质粒和药物组合物 含有所述融合多肽。
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公开(公告)号：US06972322B2
公开(公告)日：2005-12-06
申请号：US10237866
申请日：2002-09-10
IPC分类号： C12N15/09 , A61K38/00 , A61K38/16 , A61K38/21 , A61K38/22 , A61K38/38 , A61K38/43 , A61K38/55 , A61K39/00 , A61K39/44 , A61K47/48 , A61K48/00 , A61P43/00 , B65B69/00 , C07H21/04 , C07K14/47 , C07K14/52 , C07K14/53 , C07K14/535 , C07K14/745 , C07K14/755 , C07K14/76 , C07K14/765 , C07K16/00 , C07K19/00 , C12N1/19 , C12N1/21 , C12N9/72 , C12N15/12 , C12N15/62 , C12N15/81 , C12P21/02 , C12P21/06 , C12R1/645 , E05B73/00 , C12P21/04 , C12N1/20 , C12N15/00 , C12N15/63
CPC分类号： B65B69/00 , A61K38/21 , A61K38/38 , A61K47/642 , A61K47/643 , C07K14/575 , C07K14/755 , C07K14/76 , C07K14/765 , C07K2319/00 , C07K2319/02 , C07K2319/31 , C07K2319/33 , C12N9/6456 , A61K2300/00
摘要： Biologically active polypeptides comprising a therapeutically active polypeptide fused to human serum albumin or a variant thereof, methods for the preparation thereof, nucleotide sequences encoding such fusion polypeptides, expression cassettes comprising such nucleotide sequences, self-replicating plasmids containing such expression cassettes, and pharmaceutical compositions containing said fusion polypeptides.
摘要翻译： 包含与人血清白蛋白或其变体融合的治疗活性多肽的生物活性多肽，其制备方法，编码这种融合多肽的核苷酸序列，包含该核苷酸序列的表达盒，含有该表达盒的自体复制质粒和药物组合物 含有所述融合多肽。
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