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公开(公告)号：US5440026A
公开(公告)日：1995-08-08
申请号：US886633
申请日：1992-05-21
申请人： Riaz A. Khan , Keith Smith , Andrew Pelter , Jin Zhao
发明人： Riaz A. Khan , Keith Smith , Andrew Pelter , Jin Zhao
CPC分类号： C07H13/04
摘要： A method for the preparation of a sucrose 6-ester comprises:(i) reacting sucrose with a ketene acetal in the presence of an acid catalyst in an inert organic solvent to form a sucrose alkyl 4, 6-orthoester;(ii) subjecting the sucrose alkyl 4, 6-orthoester to mild acidic hydrolysis to provide a mixture of 4- and 6-monoesters of sucrose; and(iii) treating the mixture of sucrose monoesters with a base to convert the sucrose 4-ester into sucrose 6-ester. Sucralose may be prepared by chlorination of sucrose 6-esters prepared according to the invention.
摘要翻译： 蔗糖-6-酯的制备方法包括：（i）在酸催化剂存在下，在惰性有机溶剂中使蔗糖与乙烯酮缩醛反应，形成蔗糖烷基4,6-起始酯; （ii）使蔗糖烷基酯4,6-起始酯进行温和的酸性水解以提供蔗糖的4-和6-单酯的混合物; 和（iii）用碱处理蔗糖单酯的混合物以将蔗糖4-酯转化成蔗糖6-酯。 三氯蔗糖可以通过根据本发明制备的蔗糖6-酯的氯化来制备。
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公开(公告)号：US4271317A
公开(公告)日：1981-06-02
申请号：US90085
申请日：1979-10-31
申请人： Andrew Pelter , David J. Ryder
发明人： Andrew Pelter , David J. Ryder
摘要： The invention relates to alkylborane complexes with aromatic amines of the formula: ##STR1## in which R.sup.1 and R.sup.2 are the same or different (1-4C)-alkyl radicals, or together with the adjacent nitrogen atom are morpholino, piperidino or pyrrolidino radicals; R.sup.3 and R.sup.4 are independently selected from hydrogen, (1-4C)-alkyl, (1-4C)-alkoxy, di-(1-4C)-alkylamino, morpholino, piperidino and pyrrolidino; thexyl stands for 1,1,2-trimethylpropyl; and n is the integer 1 when R.sup.3 and R.sup.4 are other than nitrogen containing radicals, or the integer 1 or 2 when one of R.sup.3 and R.sup.4 is a nitrogen containing radical, or the integer 1, 2 or 3 when both R.sup.3 and R.sup.4 are nitrogen containing radicals.The complexes are more stable than thexylborane tetrahydrofuran complex, but are sufficiently reactive to be valuable as hydroborating and reducing agents.The invention also provides solutions of the complexes of formula I in organic solvents for convenient storage or subsequent synthetic use, and a process for manufacturing said complexes.A particularly convenient complex of the invention is thexylborane N,N-diethylaniline complex.
摘要翻译： 本发明涉及具有下式的芳族胺的烷基硼烷配合物：其中R 1和R 2是相同或不同的（1-4C） - 烷基，或与相邻的氮原子一起是吗啉代，哌啶子基或吡咯烷子基; R 3和R 4独立地选自氢，（1-4C） - 烷基，（1-4C） - 烷氧基，二 - （1-4C） - 烷基氨基，吗啉代，哌啶子基和吡咯烷子基; 甲氧基代表1,1,2-三甲基丙基; 当R3和R4不是含氮基团时，n是整数1，当R 3和R 4中的一个是含氮基团时，整数1或2，当R 3和R 4均为氮时，其整数为1,2或3 含有自由基。 络合物比甲基硼烷四氢呋喃络合物更稳定，但是具有足够的反应性，作为加氢硼化还原剂是有价值的。 本发明还提供式I的配合物在有机溶剂中的溶液，以方便储存或随后的合成用途，以及制备所述配合物的方法。 本发明特别方便的复合物是甲基硼烷N，N-二乙基苯胺络合物。
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公开(公告)号：US6072071A
公开(公告)日：2000-06-06
申请号：US254269
申请日：1999-03-03
申请人： Martin E Colclough , Andrew Pelter
发明人： Martin E Colclough , Andrew Pelter
IPC分类号： C07C201/02 , C07C203/04 , C07F5/02 , C07F7/18
CPC分类号： C07F7/1852 , C07C201/02 , C07C203/04
摘要： 1,2 and 1,3-dinitrate esters are prepared from polyols containing 1,2- or 1,3-diol fragments using an alkyl or aryl boronic acid to form a cyclic boronate ester derivative which is then reacted with dinitrogen pentoxide to directly generate the dinitrate ester. In the cyclic ester from the 1,2- or 1,3-hydroxyl groups are protected and other reactions may then be carried out on other parts of the molecule of which the fragment form a part, leaving the dinitrate ester to be produced subsequently in the final step. High yields are obtained at both stages.
摘要翻译： PCT No.PCT / GB97 / 02324 Sec。 371日期1999年3月3日 102（e）1999年3月3日PCT PCT 1997年9月1日PCT公布。 公开号WO98 / 09937 1991年3月12日授权日，1992年3月12日和12日，使用烷基或芳基硼酸制备含有1,2-或1,3-二醇片段的多元醇的1,3-二硝酸酯，形成环状硼酸酯衍生物，然后与 五氧化二氮直接生成二硝酸酯。 在来自1,2-或1,3-羟基的环酯中被保护，然后可以在分子的其它部分进行其它反应，其中片段形成一部分，留下硝酸酯酯随后在 最后一步。 在两个阶段获得高产率。
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公开(公告)号：US20210106900A1
公开(公告)日：2021-04-15
申请号：US16598095
申请日：2019-10-10
申请人： Andrew Pelter
发明人： Andrew Pelter
摘要： A system of batting gloves enables a batter to position his or her hands on a bat in a manner such that the batter has a proper grip of the bat. A pair of batting gloves contains markings in the middle of the fingers at locations that are approximately where a batter's middle or knocking knuckles will be positioned in the glove. When a batter wears the gloves and holds a bat, the batter will position his or her hands such that the markings on the glove fingers of the two gloves will align and form a line. When the markings are aligned and form a line, the batters' hands are positioned in a proper or preferred grip of the bat.
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