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    Continuous production of an adsorption product of a nitrooxy-functional organic compound
    2.
    发明授权
    Continuous production of an adsorption product of a nitrooxy-functional organic compound 有权

    公开(公告)号：US11758925B2

    公开(公告)日：2023-09-19

    申请号：US17257763

    申请日：2019-07-12

    Applicant: DSM IP ASSETS B.V.

    Inventor： Peter Riebel ,  Kai Urban

    IPC: A23K20/105 ,  A23K20/28 ,  A23K50/10 ,  C07C203/04

    CPC classification number: A23K20/105 ,  A23K20/28 ,  A23K50/10 ,  C07C203/04

    Abstract: The invention relates to a process for the continuous production of an adsorption product of a nitrooxy-functional organic compound adsorbed on the surface of a particulate adsorbent material, the process comprising the steps of: continuously feeding particulate adsorbent material into an elongated cavity; continuously conveying the material within the cavity in a downstream direction; continuously spraying a liquid adsorbate onto the particulate adsorbent material, wherein the liquid adsorbate comprises the nitrooxy-functional organic compound; continuously agitating the mixture thus obtained to form the adsorption product; and continuously removing the adsorption product from the cavity. The invention further relates to an adsorption product obtained by such process and the use of such adsorption product in ruminant nutrition.

    Process for the production of chemical compounds from carbon dioxide
    7.
    发明授权
    Process for the production of chemical compounds from carbon dioxide 有权
    从二氧化碳生产化学化合物的方法

    公开(公告)号：US09273020B2

    公开(公告)日：2016-03-01

    申请号：US14394508

    申请日：2013-04-11

    Applicant: Haldor Topsøe A/S

    Inventor： Niels Christian Schjødt ,  John Bøgild Hansen ,  Claus Friis Pedersen

    IPC: C07D305/00 ,  C07C69/96 ,  C07C51/14 ,  C07D305/12 ,  C07C67/38 ,  C07C68/00 ,  C07C201/02 ,  C07D301/04 ,  C25B1/02 ,  C25B15/08 ,  C25B1/00 ,  C07C67/035 ,  C07C68/04

    CPC classification number: C07D305/12 ,  C07C51/14 ,  C07C67/035 ,  C07C67/38 ,  C07C68/005 ,  C07C68/04 ,  C07C201/02 ,  C07D301/04 ,  C25B1/00 ,  C25B1/02 ,  C25B15/08 ,  Y02E60/366 ,  Y02P20/133 ,  Y02P20/134 ,  Y02P20/582 ,  C07C203/04 ,  C07C69/96 ,  C07C53/124 ,  C07C69/24

    Abstract: Process for the production of a chemical compound from a carbon dioxide starting material, comprising the steps of a) providing a feed stream consisting mainly of carbon dioxide; b) electrolyzing in an electrolysis stage the carbon dioxide in the feed stream to a first gas stream containing carbon monoxide and a second gas stream containing oxygen, wherein the molar ratio between carbon monoxide and oxygen is about 1:0.5 in an electrolysis stage; c) adjusting the composition of the first gas stream or the second gas stream or both gas streams to include carbon dioxide, either by operating at less than full conversion of CO2 or by sweeping one or both gas streams with a gas containing CO2 or by at some stage between the electrolysis cell and the oxidative carbonylation reactor diluting one or both gas streams with a gas containing CO2; all while maintaining an overall molar ratio of carbon monoxide to oxygen of about 1:0.5; and d) introducing the first and second process stream into a reaction stage and reacting the first and second process stream combined or in succession with a substrate to the chemical compound by means of an oxidative carbonylation reaction with the carbon monoxide and oxygen contained in the process feed stream.

    Abstract translation: 用于从二氧化碳原料生产化合物的方法，包括以下步骤：a）提供主要由二氧化碳组成的进料流; b）在电解阶段中将进料流中的二氧化碳电解成含有一氧化碳和含有氧的第二气流的第一气流，其中在电解阶段一氧化碳和氧之间的摩尔比为约1:0.5; c）调节第一气流或第二气流或两种气流的组成以包括二氧化碳，或者通过以少于二氧化碳的全部转化率进行操作，或者通过用含有CO 2的气体或通过在 在电解池和氧化羰基化反应器之间的某个阶段，用含CO 2的气体稀释一种或两种气流; 同时保持一氧化碳与氧的总摩尔比为约1:0.5; 和d）将第一和第二工艺流引入反应阶段，并通过与该方法中所含的一氧化碳和氧气进行氧化羰基化反应，将第一和第二工艺流与底物组合或连续地与化学化合物反应 饲料流。

    NITRIC OXIDE RELEASING AMINO ACID ESTER FOR TREATMENT OF PULMONARY HYPERTENSION AND OTHER RESPIRATORY CONDITIONS
    9.
    发明申请
    NITRIC OXIDE RELEASING AMINO ACID ESTER FOR TREATMENT OF PULMONARY HYPERTENSION AND OTHER RESPIRATORY CONDITIONS 审中-公开
    用于治疗肺动脉高压和其他呼吸道状况的硝酸氧化酶释放氨基酸

    公开(公告)号：US20150093338A1

    公开(公告)日：2015-04-02

    申请号：US14509287

    申请日：2014-10-08

    Applicant: Michael Farber

    Inventor： Michael Farber

    IPC: C07C203/04 ,  A61K45/06 ,  A61K31/22

    CPC classification number: C07C203/04 ,  A61K9/0078 ,  A61K31/22 ,  A61K31/223 ,  A61K45/06 ,  A61K2300/00

    Abstract: There is provided compositions and methods for the treatment of respiratory conditions such as pulmonary hypertension and sickle-cell disease in a patient in need thereof. The composition and method are for treating a patient in need thereof by inhalation of a composition containing amino acid ester compounds comprising at least one nitric oxide releasing group and pharmaceutical salts thereof.

    Abstract translation: 提供了在有需要的患者中治疗呼吸道疾病如肺动脉高压和镰状细胞病的组合物和方法。 组合物和方法用于通过吸入包含至少一种一氧化氮释放基团的氨基酸酯化合物及其药学盐的组合物来治疗有需要的患者。

    PROCESS FOR THE PRODUCTION OF CHEMICAL COMPOUNDS FROM CARBON DIOXIDE
    10.
    发明申请
    PROCESS FOR THE PRODUCTION OF CHEMICAL COMPOUNDS FROM CARBON DIOXIDE 有权
    从二氧化碳生产化学化合物的方法

    公开(公告)号：US20150057458A1

    公开(公告)日：2015-02-26

    申请号：US14394508

    申请日：2013-04-11

    Applicant: Haldor Topsøe A/S

    Inventor： Niels Christian Schjødt ,  John Bøgild Hansen ,  Claus Friis Pedersen

    IPC: C07D305/12 ,  C25B1/02 ,  C25B1/00 ,  C07C68/04 ,  C07C67/035

    CPC classification number: C07D305/12 ,  C07C51/14 ,  C07C67/035 ,  C07C67/38 ,  C07C68/005 ,  C07C68/04 ,  C07C201/02 ,  C07D301/04 ,  C25B1/00 ,  C25B1/02 ,  C25B15/08 ,  Y02E60/366 ,  Y02P20/133 ,  Y02P20/134 ,  Y02P20/582 ,  C07C203/04 ,  C07C69/96 ,  C07C53/124 ,  C07C69/24

    Abstract: Process for the production of a chemical compound from a carbon dioxide starting material, comprising the steps of a) providing a feed stream consisting mainly of carbon dioxide; b) electrolysing in an electrolysis stage the carbon dioxide in the feed stream to a first gas stream containing carbon monoxide and a second gas stream containing oxygen, wherein the molar ratio between carbon monoxide and oxygen is about 1:0.5 in an electrolysis stage; c) adjusting the composition of the first gas stream or the second gas stream or both gas streams to include carbon dioxide, either by operating at less than full conversion of CO2 or by sweeping one or both gas streams with a gas containing CO2 or by at some stage between the electrolysis cell and the oxidative carbonylation reactor diluting one or both gas streams with a gas containing CO2; all while maintaining an overall molar ratio of carbon monoxide to oxygen of about 1:0.5; and d) introducing the first and second process stream into a reaction stage and reacting the first and second process stream combined or in succession with a substrate to the chemical compound by means of an oxidative carbonylation reaction with the carbon monoxide and oxygen contained in the process feed stream.

    Abstract translation: 用于从二氧化碳原料生产化合物的方法，包括以下步骤：a）提供主要由二氧化碳组成的进料流; b）在电解阶段将电解中的二氧化碳电解成含有一氧化碳和含有氧的第二气流的第一气流，其中一氧化碳与氧之间的摩尔比在电解阶段为约1:0.5; c）调节第一气流或第二气流或两种气流的组成以包括二氧化碳，或者通过以少于二氧化碳的全部转化率进行操作，或者通过用含有CO 2的气体或通过在 在电解池和氧化羰基化反应器之间的某个阶段，用含CO 2的气体稀释一种或两种气流; 同时保持一氧化碳与氧的总摩尔比为约1:0.5; 和d）将第一和第二工艺流引入反应阶段，并通过与该方法中所含的一氧化碳和氧气进行氧化羰基化反应，将第一和第二工艺流与底物组合或连续地与化学化合物反应 饲料流。

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