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40 条记录 (耗时 0.021 秒)

    DNA Sequencing System
    2.
    发明申请
    DNA Sequencing System 有权
    DNA测序系统

    公开(公告)号：US20100103416A1

    公开(公告)日：2010-04-29

    申请号：US12630683

    申请日：2009-12-03

    申请人： Mark F. OLDHAM ,  Eric S. Nordman ,  Richard T. Reel ,  Janice S. Shigeura

    发明人： Mark F. OLDHAM ,  Eric S. Nordman ,  Richard T. Reel ,  Janice S. Shigeura

    IPC分类号： G01N21/00

    CPC分类号： G01N27/44721 ,  B82Y10/00 ,  B82Y20/00 ,  G01N2015/149 ,  G01N2015/1497

    摘要： An apparatus for detecting labeled beads is provided. The apparatus can include: one or more irradiation sources disposed for irradiating the one or more detection zones with radiation; at least one detector disposed for collecting charges corresponding to light signals emitted from labeled beads in the one or more detection zones, which have been excited by the radiation; and a system coupled to the at least one detector for effecting time delay integration of the charges by accumulating the charges before reading the charges at the output of the at least one detector.

    摘要翻译： 提供了一种用于检测标记珠粒的装置。 该装置可以包括：一个或多个辐射源，被设置用于用辐射照射一个或多个检测区域; 至少一个检测器被设置用于收集对应于已经被辐射激发的一个或多个检测区域中的标记珠子发射的光信号的电荷; 以及耦合到所述至少一个检测器的系统，用于通过在读取至少一个检测器的输出端的电荷之前累积电荷来实现电荷的时间延迟积分。

    System for detecting markers
    3.
    发明授权
    System for detecting markers 有权
    检测标记系统

    公开(公告)号：US07636160B2

    公开(公告)日：2009-12-22

    申请号：US12321781

    申请日：2009-01-26

    申请人： Mark F. Oldham ,  Eric S. Nordman ,  Richard T. Reel ,  John S. Shigeura ,  Janice G. Shigeura, legal representative

    发明人： Mark F. Oldham ,  Eric S. Nordman ,  Richard T. Reel ,  John S. Shigeura

    IPC分类号： G01N21/00

    CPC分类号： G01N27/44721 ,  B82Y10/00 ,  B82Y20/00 ,  G01N2015/149 ,  G01N2015/1497

    摘要： An apparatus for detecting labeled beads is provided. The apparatus can include: one or more irradiation sources disposed for irradiating the one or more detection zones with radiation; at least one detector disposed for collecting charges corresponding to light signals emitted from labeled beads in the one or more detection zones, which have been excited by the radiation; and a system coupled to the at least one detector for effecting time delay integration of the charges by accumulating the charges before reading the charges at the output of the at least one detector.

    摘要翻译： 提供了一种用于检测标记珠粒的装置。 该装置可以包括：一个或多个辐射源，被设置用于用辐射照射一个或多个检测区域; 至少一个检测器被设置用于收集对应于已经被辐射激发的一个或多个检测区域中的标记珠子发射的光信号的电荷; 以及耦合到所述至少一个检测器的系统，用于通过在读取至少一个检测器的输出端的电荷之前累积电荷来实现电荷的时间延迟积分。

    Multi-channel capillary electrophoresis device and method
    5.
    发明授权
    Multi-channel capillary electrophoresis device and method 有权

    公开(公告)号：US06596140B2

    公开(公告)日：2003-07-22

    申请号：US09846855

    申请日：2001-05-01

    申请人： Eric S. Nordman ,  Richard T. Reel

    发明人： Eric S. Nordman ,  Richard T. Reel

    IPC分类号： G01N27447

    CPC分类号： G01N27/44704 ,  G01N27/44721 ,  G01N27/44782

    摘要： Embodiments of a device and method are described which provide for control over the distortion of a sample zone upon exiting an electrophoresis separation channel. According to the teachings herein (i) the downstream regions of the channels, near the outlet ends, and/or (ii) the detection chamber, is/are configured so that distortion of one or more sample zones passing from the channels into and across the detection chamber can be controlled (e.g., reduced) in a fashion affording enhanced detectability. In certain embodiments, the lumens along the end regions of the separation channels progressively expand.

    DNA Sequencing System
    6.
    发明申请
    DNA Sequencing System 有权
    DNA测序系统

    公开(公告)号：US20120196296A1

    公开(公告)日：2012-08-02

    申请号：US13442143

    申请日：2012-04-09

    申请人： Mark E. Oldham ,  Eric S. Nordman ,  Richard T. Reel ,  John S. Shigeura ,  Janice G. Shigeura

    发明人： Mark E. Oldham ,  Eric S. Nordman ,  Richard T. Reel ,  John S. Shigeura ,  Janice G. Shigeura

    IPC分类号： G01N21/64

    CPC分类号： G01N27/44721 ,  B82Y10/00 ,  B82Y20/00 ,  G01N2015/149 ,  G01N2015/1497

    摘要： An apparatus for detecting labeled beads is provided. The apparatus can include: one or more irradiation sources disposed for irradiating the one or more detection zones with radiation; at least one detector disposed for collecting charges corresponding to light signals emitted from labeled beads in the one or more detection zones, which have been excited by the radiation; and a system coupled to the at least one detector for effecting time delay integration of the charges by accumulating the charges before reading the charges at the output of the at least one detector.

    摘要翻译： 提供了一种用于检测标记珠粒的装置。 该装置可以包括：一个或多个辐射源，被设置用于用辐射照射一个或多个检测区域; 至少一个检测器被设置用于收集对应于已经被辐射激发的一个或多个检测区域中的标记珠子发射的光信号的电荷; 以及耦合到所述至少一个检测器的系统，用于通过在读取至少一个检测器的输出端的电荷之前累积电荷来实现电荷的时间延迟积分。

    Optical System and Method for Optically Analyzing Light From a Sample
    8.
    发明申请
    Optical System and Method for Optically Analyzing Light From a Sample 审中-公开
    用于从样品光学分析光的光学系统和方法

    公开(公告)号：US20090116028A1

    公开(公告)日：2009-05-07

    申请号：US12352742

    申请日：2009-01-13

    申请人： Richard T. Reel

    发明人： Richard T. Reel

    IPC分类号： G01J3/45 ,  G01J3/28 ,  G01N21/00

    CPC分类号： G01J3/02 ,  G01J3/0208 ,  G01J3/0229 ,  G01J3/0262 ,  G01J3/0294 ,  G01J3/04 ,  G01J3/2803 ,  G01N21/05 ,  G01N21/31 ,  G01N27/44721 ,  G01N2021/0346

    摘要： An optical system for analyzing light from a plurality of samples is provided. The optical system includes a plurality of holders adapted to have samples located therein, a collection lens, a transmission grating, and a reimaging lens. The collection lens is configured to receive and substantially collimate light from the samples. The transmission grating is configured to spectrally disperse the substantially collimated light from the collection lens. The reimaging lens is configured to receive the light from the light dispersing element and direct the light onto a light detection device. A method of optically analyzing at least one sample is also provided.

    摘要翻译： 提供了一种用于分析来自多个样品的光的光学系统。 光学系统包括多个保持器，其适于使样本位于其中，收集透镜，透射光栅和再成像透镜。 收集透镜被配置为接收并基本上准直来自样品的光。 透射光栅被配置为光谱地分散来自收集透镜的基本上准直的光。 该成像透镜被配置为接收来自光分散元件的光并将光引导到光检测装置上。 还提供了一种光学分析至少一个样品的方法。

    Time-delay integration in detection of labeled beads
    9.
    发明申请
    Time-delay integration in detection of labeled beads 有权
    标记珠的检测时延整合

    公开(公告)号：US20090021735A1

    公开(公告)日：2009-01-22

    申请号：US12283957

    申请日：2008-09-17

    申请人： Mark F. Oldham ,  Eric S. Nordman ,  Richard T. Reel ,  John S. Shigeura ,  Janice G. Shigeura

    发明人： Mark F. Oldham ,  Eric S. Nordman ,  Richard T. Reel ,  John S. Shigeura ,  Janice G. Shigeura

    IPC分类号： G01N21/62

    CPC分类号： G01N27/44721 ,  B82Y10/00 ,  B82Y20/00 ,  G01N2015/149 ,  G01N2015/1497

    摘要： An apparatus for detecting labeled beads is provided. The apparatus can include: one or more irradiation sources disposed for irradiating the one or more detection zones with radiation; at least one detector disposed for collecting charges corresponding to light signals emitted from labeled beads in the one or more detection zones, which have been excited by the radiation; and a system coupled to the at least one detector for effecting time delay integration of the charges by accumulating the charges before reading the charges at the output of the at least one detector.

    摘要翻译： 提供了一种用于检测标记珠粒的装置。 该装置可以包括：一个或多个辐射源，被设置用于用辐射照射一个或多个检测区域; 至少一个检测器被设置用于收集对应于已经被辐射激发的一个或多个检测区域中的标记珠子发射的光信号的电荷; 以及耦合到所述至少一个检测器的系统，用于通过在读取至少一个检测器的输出端的电荷之前累积电荷来实现电荷的时间延迟积分。